ID   SHL2B_BOVIN             Reviewed;         161 AA.
AC   A6QQ93;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   21-AUG-2007, sequence version 1.
DT   25-MAY-2022, entry version 65.
DE   RecName: Full=Protein shisa-like-2B;
GN   Name=SHISAL2B; Synonyms=FAM159B;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Hypothalamus;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the shisa family. {ECO:0000305}.
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DR   EMBL; BC149710; AAI49711.1; -; mRNA.
DR   RefSeq; NP_001093843.1; NM_001100373.2.
DR   AlphaFoldDB; A6QQ93; -.
DR   SMR; A6QQ93; -.
DR   STRING; 9913.ENSBTAP00000012465; -.
DR   PaxDb; A6QQ93; -.
DR   Ensembl; ENSBTAT00000012465; ENSBTAP00000012465; ENSBTAG00000009468.
DR   GeneID; 515994; -.
DR   KEGG; bta:515994; -.
DR   CTD; 100132916; -.
DR   VEuPathDB; HostDB:ENSBTAG00000009468; -.
DR   VGNC; VGNC:28738; SHISAL2B.
DR   eggNOG; ENOG502S1JE; Eukaryota.
DR   GeneTree; ENSGT00940000161622; -.
DR   HOGENOM; CLU_140078_0_0_1; -.
DR   InParanoid; A6QQ93; -.
DR   OMA; YMWSLSV; -.
DR   OrthoDB; 1480293at2759; -.
DR   TreeFam; TF335848; -.
DR   Proteomes; UP000009136; Chromosome 20.
DR   Bgee; ENSBTAG00000009468; Expressed in laryngeal cartilage and 47 other tissues.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR026910; Shisa.
DR   PANTHER; PTHR31395; PTHR31395; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..161
FT                   /note="Protein shisa-like-2B"
FT                   /id="PRO_0000317722"
FT   TRANSMEM        65..85
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          115..134
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   161 AA;  17880 MW;  88799AF875A132CA CRC64;
     MSEASRVCSG YYSLNHSFVE PFQCPRRGEG ATLLYCCGFA DLKYCCSEPG SYFPYKHSYM
     WSLSIGALIG LGIAALVLLA FVISVCVLCY LFLYTKPQRL DTGLKLQHLE AVSTQEGNSN
     RKSKAPRSNA ASNSTNETFY EADDIIQEKT MDTTQINTAY C