SHN2_ARATH
ID SHN2_ARATH Reviewed; 189 AA.
AC Q9LFN7;
DT 12-JUN-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 03-AUG-2022, entry version 128.
DE RecName: Full=Ethylene-responsive transcription factor SHINE 2;
GN Name=SHN2; Synonyms=ERF004; OrderedLocusNames=At5g11190; ORFNames=F2I11.80;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RA Pan Y., Gong W., Liu D., Fu Q., Mei W.-Q., Song W.-Q., Ma L.-G., Luo J.-C.,
RA Deng X.-W., Zhu Y.-X.;
RT "Molecular cloning, expression, phylogenetic and functional
RT characterization of the Arabidopsis AP2/EREBP transcription factor
RT family.";
RL Submitted (FEB-2004) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130714; DOI=10.1038/35048507;
RA Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E.,
RA Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M.,
RA Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K.,
RA Okumura S., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M.,
RA Yasuda M., Sato S., de la Bastide M., Huang E., Spiegel L., Gnoj L.,
RA O'Shaughnessy A., Preston R., Habermann K., Murray J., Johnson D.,
RA Rohlfing T., Nelson J., Stoneking T., Pepin K., Spieth J., Sekhon M.,
RA Armstrong J., Becker M., Belter E., Cordum H., Cordes M., Courtney L.,
RA Courtney W., Dante M., Du H., Edwards J., Fryman J., Haakensen B.,
RA Lamar E., Latreille P., Leonard S., Meyer R., Mulvaney E., Ozersky P.,
RA Riley A., Strowmatt C., Wagner-McPherson C., Wollam A., Yoakum M., Bell M.,
RA Dedhia N., Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D.,
RA Baker J., Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A.,
RA Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I.,
RA Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T.,
RA Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S., Langham S.-A.,
RA McCullagh B., Robben J., Grymonprez B., Zimmermann W., Ramsperger U.,
RA Wedler H., Balke K., Wedler E., Peters S., van Staveren M., Dirkse W.,
RA Mooijman P., Klein Lankhorst R., Weitzenegger T., Bothe G., Rose M.,
RA Hauf J., Berneiser S., Hempel S., Feldpausch M., Lamberth S.,
RA Villarroel R., Gielen J., Ardiles W., Bents O., Lemcke K., Kolesov G.,
RA Mayer K.F.X., Rudd S., Schoof H., Schueller C., Zaccaria P., Mewes H.-W.,
RA Bevan M., Fransz P.F.;
RT "Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana.";
RL Nature 408:823-826(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP FUNCTION, TISSUE SPECIFICITY, AND DEVELOPMENTAL STAGE.
RX PubMed=15319479; DOI=10.1105/tpc.104.022897;
RA Aharoni A., Dixit S., Jetter R., Thoenes E., van Arkel G., Pereira A.;
RT "The SHINE clade of AP2 domain transcription factors activates wax
RT biosynthesis, alters cuticle properties, and confers drought tolerance when
RT overexpressed in Arabidopsis.";
RL Plant Cell 16:2463-2480(2004).
RN [5]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=16407444; DOI=10.1104/pp.105.073783;
RA Nakano T., Suzuki K., Fujimura T., Shinshi H.;
RT "Genome-wide analysis of the ERF gene family in Arabidopsis and rice.";
RL Plant Physiol. 140:411-432(2006).
CC -!- FUNCTION: Promotes cuticle formation by inducing the expression of
CC enzymes involved in wax biosynthesis. Probably acts as a
CC transcriptional activator. Binds to the GCC-box pathogenesis-related
CC promoter element. May be involved in the regulation of gene expression
CC by stress factors and by components of stress signal transduction
CC pathways (By similarity). {ECO:0000250, ECO:0000269|PubMed:15319479}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- TISSUE SPECIFICITY: In flowers. {ECO:0000269|PubMed:15319479}.
CC -!- DEVELOPMENTAL STAGE: The SHN2 gene shows a pattern of expression
CC associated with anther and silique dehiscence. Expressed in the stomium
CC region when tapetum degeneration is initiated in the anther. Up to
CC anthesis and until stamens fell off the senescing flower, restricted to
CC the anther dehiscence zone. Subsequently, when petals and sepals
CC withered, found at the bottom of each valve. During silique
CC development, strongly expressed along the valve margin-replum boundary.
CC {ECO:0000269|PubMed:15319479}.
CC -!- SIMILARITY: Belongs to the AP2/ERF transcription factor family. ERF
CC subfamily. {ECO:0000305}.
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DR EMBL; AY560865; AAT44932.1; -; mRNA.
DR EMBL; AL360314; CAB96654.1; -; Genomic_DNA.
DR EMBL; CP002688; AED91644.1; -; Genomic_DNA.
DR RefSeq; NP_196680.1; NM_121157.2.
DR AlphaFoldDB; Q9LFN7; -.
DR SMR; Q9LFN7; -.
DR BioGRID; 16267; 2.
DR STRING; 3702.AT5G11190.1; -.
DR PaxDb; Q9LFN7; -.
DR PRIDE; Q9LFN7; -.
DR EnsemblPlants; AT5G11190.1; AT5G11190.1; AT5G11190.
DR GeneID; 830989; -.
DR Gramene; AT5G11190.1; AT5G11190.1; AT5G11190.
DR KEGG; ath:AT5G11190; -.
DR Araport; AT5G11190; -.
DR TAIR; locus:2148022; AT5G11190.
DR eggNOG; ENOG502RXNN; Eukaryota.
DR HOGENOM; CLU_042594_3_0_1; -.
DR InParanoid; Q9LFN7; -.
DR OMA; WVMRIEL; -.
DR OrthoDB; 1336707at2759; -.
DR PhylomeDB; Q9LFN7; -.
DR PRO; PR:Q9LFN7; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9LFN7; baseline and differential.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IDA:TAIR.
DR GO; GO:0009873; P:ethylene-activated signaling pathway; IEA:UniProtKB-KW.
DR CDD; cd00018; AP2; 1.
DR Gene3D; 3.30.730.10; -; 1.
DR InterPro; IPR001471; AP2/ERF_dom.
DR InterPro; IPR036955; AP2/ERF_dom_sf.
DR InterPro; IPR016177; DNA-bd_dom_sf.
DR Pfam; PF00847; AP2; 1.
DR PRINTS; PR00367; ETHRSPELEMNT.
DR SMART; SM00380; AP2; 1.
DR SUPFAM; SSF54171; SSF54171; 1.
DR PROSITE; PS51032; AP2_ERF; 1.
PE 2: Evidence at transcript level;
KW Activator; DNA-binding; Ethylene signaling pathway; Nucleus;
KW Reference proteome; Transcription; Transcription regulation.
FT CHAIN 1..189
FT /note="Ethylene-responsive transcription factor SHINE 2"
FT /id="PRO_0000290370"
FT DNA_BIND 6..63
FT /note="AP2/ERF"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00366"
SQ SEQUENCE 189 AA; 21409 MW; 12A21D79FFACFA9B CRC64;
MVHSRKFRGV RQRQWGSWVS EIRHPLLKRR VWLGTFETAE AAARAYDQAA LLMNGQNAKT
NFPVVKSEEG SDHVKDVNSP LMSPKSLSEL LNAKLRKSCK DLTPSLTCLR LDTDSSHIGV
WQKRAGSKTS PTWVMRLELG NVVNESAVDL GLTTMNKQNV EKEEEEEEAI ISDEDQLAME
MIEELLNWS
