BH010_ARATH
ID BH010_ARATH Reviewed; 458 AA.
AC Q84TK1; Q9SJX4;
DT 16-DEC-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2003, sequence version 1.
DT 25-MAY-2022, entry version 120.
DE RecName: Full=Transcription factor bHLH10;
DE AltName: Full=Basic helix-loop-helix protein 10;
DE Short=AtbHLH10;
DE Short=bHLH 10;
DE AltName: Full=Transcription factor EN 23;
DE AltName: Full=bHLH transcription factor bHLH010;
GN Name=BHLH10; Synonyms=EN23; OrderedLocusNames=At2g31220; ORFNames=F16D14.6;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP NUCLEOTIDE SEQUENCE [MRNA] OF 12-458, INDUCTION BY UV LIGHT, GENE FAMILY,
RP AND NOMENCLATURE.
RC STRAIN=cv. Columbia;
RX PubMed=12679534; DOI=10.1093/molbev/msg088;
RA Heim M.A., Jakoby M., Werber M., Martin C., Weisshaar B., Bailey P.C.;
RT "The basic helix-loop-helix transcription factor family in plants: a
RT genome-wide study of protein structure and functional diversity.";
RL Mol. Biol. Evol. 20:735-747(2003).
RN [6]
RP GENE FAMILY.
RX PubMed=12897250; DOI=10.1105/tpc.013839;
RA Toledo-Ortiz G., Huq E., Quail P.H.;
RT "The Arabidopsis basic/helix-loop-helix transcription factor family.";
RL Plant Cell 15:1749-1770(2003).
RN [7]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=14600211; DOI=10.1105/tpc.151140;
RA Bailey P.C., Martin C., Toledo-Ortiz G., Quail P.H., Huq E., Heim M.A.,
RA Jakoby M., Werber M., Weisshaar B.;
RT "Update on the basic helix-loop-helix transcription factor gene family in
RT Arabidopsis thaliana.";
RL Plant Cell 15:2497-2502(2003).
CC -!- SUBUNIT: Homodimer. {ECO:0000305}.
CC -!- INTERACTION:
CC Q84TK1; Q0WNR2: BHLH90; NbExp=3; IntAct=EBI-15200952, EBI-15216058;
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981}.
CC -!- INDUCTION: By UV treatment. {ECO:0000269|PubMed:12679534}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAD20667.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AC006593; AAD20667.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002685; ANM62996.1; -; Genomic_DNA.
DR EMBL; BT005711; AAO64131.1; -; mRNA.
DR EMBL; BT008608; AAP40433.1; -; mRNA.
DR EMBL; AK228592; BAF00507.1; -; mRNA.
DR EMBL; AF251695; AAL55717.1; -; mRNA.
DR PIR; A84718; A84718.
DR RefSeq; NP_001318326.1; NM_001336324.1.
DR RefSeq; NP_180680.2; NM_128678.5.
DR AlphaFoldDB; Q84TK1; -.
DR BioGRID; 3027; 107.
DR IntAct; Q84TK1; 105.
DR STRING; 3702.AT2G31220.1; -.
DR PaxDb; Q84TK1; -.
DR PRIDE; Q84TK1; -.
DR EnsemblPlants; AT2G31220.2; AT2G31220.2; AT2G31220.
DR GeneID; 817679; -.
DR Gramene; AT2G31220.2; AT2G31220.2; AT2G31220.
DR KEGG; ath:AT2G31220; -.
DR Araport; AT2G31220; -.
DR TAIR; locus:2042486; AT2G31220.
DR eggNOG; ENOG502QQIQ; Eukaryota.
DR HOGENOM; CLU_045325_0_0_1; -.
DR InParanoid; Q84TK1; -.
DR OrthoDB; 948814at2759; -.
DR PhylomeDB; Q84TK1; -.
DR PRO; PR:Q84TK1; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q84TK1; baseline and differential.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0048658; P:anther wall tapetum development; IGI:TAIR.
DR GO; GO:0052543; P:callose deposition in cell wall; IGI:TAIR.
DR GO; GO:0009555; P:pollen development; IGI:TAIR.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IEP:TAIR.
DR CDD; cd18918; bHLH_AtMYC1_like; 1.
DR Gene3D; 4.10.280.10; -; 1.
DR InterPro; IPR045895; bHLH91-like.
DR InterPro; IPR011598; bHLH_dom.
DR InterPro; IPR036638; HLH_DNA-bd_sf.
DR InterPro; IPR045896; MYC1-like_bHLH.
DR PANTHER; PTHR46834; PTHR46834; 1.
DR Pfam; PF00010; HLH; 1.
DR SMART; SM00353; HLH; 1.
DR SUPFAM; SSF47459; SSF47459; 1.
DR PROSITE; PS50888; BHLH; 1.
PE 1: Evidence at protein level;
KW DNA-binding; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..458
FT /note="Transcription factor bHLH10"
FT /id="PRO_0000358727"
FT DOMAIN 243..292
FT /note="bHLH"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00981"
FT REGION 1..49
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 315..338
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 458 AA; 51459 MW; 718BD3F9A1F49BE7 CRC64;
MEEERESLYE EMGCFDPNTP AEVTVESSFS QAEPPPPPPQ VLVAGSTSNS NCSVEVEELS
EFHLSPQDCP QASSTPLQFH INPPPPPPPP CDQLHNNLIH QMASHQQQHS NWDNGYQDFV
NLGPNSATTP DLLSLLHLPR CSLPPNHHPS SMLPTSFSDI MSSSSAAAVM YDPLFHLNFP
MQPRDQNQLR NGSCLLGVED QIQMDANGGM NVLYFEGANN NNGGFENEIL EFNNGVTRKG
RGSRKSRTSP TERERRVHFN DRFFDLKNLI PNPTKIDRAS IVGEAIDYIK ELLRTIEEFK
MLVEKKRCGR FRSKKRARVG EGGGGEDQEE EEDTVNYKPQ SEVDQSCFNK NNNNSLRCSW
LKRKSKVTEV DVRIIDDEVT IKLVQKKKIN CLLFTTKVLD QLQLDLHHVA GGQIGEHYSF
LFNTKICEGS CVYASGIADT LMEVVEKQYM EAVPSNGY
