ABF1_CAEEL
ID ABF1_CAEEL Reviewed; 85 AA.
AC G5EGC4;
DT 29-OCT-2014, integrated into UniProtKB/Swiss-Prot.
DT 14-DEC-2011, sequence version 1.
DT 03-AUG-2022, entry version 49.
DE RecName: Full=Antibacterial factor-related peptide 1 {ECO:0000303|PubMed:11772394};
DE Flags: Precursor;
GN Name=abf-1 {ECO:0000312|WormBase:C50F2.9};
GN ORFNames=C50F2.9 {ECO:0000312|WormBase:C50F2.9};
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239 {ECO:0000312|EMBL:BAA89489.1};
RN [1] {ECO:0000312|EMBL:BAA89489.1}
RP NUCLEOTIDE SEQUENCE [MRNA], TISSUE SPECIFICITY, AND DEVELOPMENTAL STAGE.
RX PubMed=11772394; DOI=10.1042/0264-6021:3610221;
RA Kato Y., Aizawa T., Hoshino H., Kawano K., Zhang H.;
RT "abf-1 and abf-2, ASABF-type antimicrobial peptide genes in Caenorhabditis
RT elegans.";
RL Biochem. J. 361:221-230(2002).
RN [2] {ECO:0000312|EMBL:CCD67777.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2 {ECO:0000312|EMBL:CCD67777.1};
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC -!- TISSUE SPECIFICITY: Expressed in the pharynx and body wall muscle.
CC {ECO:0000269|PubMed:11772394}.
CC -!- DEVELOPMENTAL STAGE: Expressed in all larval and adult stages but not
CC in pre-hatching embryos. {ECO:0000269|PubMed:11772394}.
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DR EMBL; AB029809; BAA89489.1; -; mRNA.
DR EMBL; FO080915; CCD67777.1; -; Genomic_DNA.
DR RefSeq; NP_491253.1; NM_058852.5.
DR AlphaFoldDB; G5EGC4; -.
DR SMR; G5EGC4; -.
DR STRING; 6239.C50F2.9; -.
DR PaxDb; G5EGC4; -.
DR EnsemblMetazoa; C50F2.9.1; C50F2.9.1; WBGene00000012.
DR GeneID; 266827; -.
DR KEGG; cel:CELE_C50F2.9; -.
DR CTD; 266827; -.
DR WormBase; C50F2.9; CE27879; WBGene00000012; abf-1.
DR GeneTree; ENSGT00970000196640; -.
DR HOGENOM; CLU_172752_1_0_1; -.
DR InParanoid; G5EGC4; -.
DR OMA; CARMDVF; -.
DR PhylomeDB; G5EGC4; -.
DR PRO; PR:G5EGC4; -.
DR Proteomes; UP000001940; Chromosome I.
DR Bgee; WBGene00000012; Expressed in adult organism and 3 other tissues.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0098542; P:defense response to other organism; IEA:InterPro.
DR Gene3D; 3.30.30.110; -; 1.
DR InterPro; IPR031770; Abf-1/2.
DR InterPro; IPR038204; Abf-1/2_sf.
DR PANTHER; PTHR37971; PTHR37971; 1.
DR Pfam; PF16839; Antimicrobial25; 1.
PE 2: Evidence at transcript level;
KW Reference proteome; Secreted; Signal.
FT SIGNAL 1..19
FT /evidence="ECO:0000255"
FT PEPTIDE 20..85
FT /note="Antibacterial factor-related peptide 1"
FT /evidence="ECO:0000255"
FT /id="PRO_0000430529"
SQ SEQUENCE 85 AA; 9070 MW; E64F60E92AFA0EDD CRC64;
MLYFCLLLVL LLPNNGVSSE ASCARMDVPV MQRIAQGLCT SSCTAQKCMT GICKKVDSHP
TCFCGGCSNA NDVSLDTLIS QLPHN