ID   SHQ1_DANRE              Reviewed;         585 AA.
AC   A1L1R0;
DT   11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT   06-FEB-2007, sequence version 1.
DT   03-AUG-2022, entry version 67.
DE   RecName: Full=Protein SHQ1 homolog;
GN   Name=shq1; ORFNames=zgc:158255;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Kidney;
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-536 AND THR-540, AND
RP   IDENTIFICATION BY MASS SPECTROMETRY.
RC   TISSUE=Embryo;
RX   PubMed=18307296; DOI=10.1021/pr700667w;
RA   Lemeer S., Pinkse M.W.H., Mohammed S., van Breukelen B., den Hertog J.,
RA   Slijper M., Heck A.J.R.;
RT   "Online automated in vivo zebrafish phosphoproteomics: from large-scale
RT   analysis down to a single embryo.";
RL   J. Proteome Res. 7:1555-1564(2008).
CC   -!- FUNCTION: Required for the quantitative accumulation of H/ACA
CC       ribonucleoproteins (RNPs). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol {ECO:0000250}. Nucleus,
CC       nucleoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SHQ1 family. {ECO:0000305}.
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DR   EMBL; BC129178; AAI29179.1; -; mRNA.
DR   AlphaFoldDB; A1L1R0; -.
DR   SMR; A1L1R0; -.
DR   STRING; 7955.ENSDARP00000036580; -.
DR   iPTMnet; A1L1R0; -.
DR   PaxDb; A1L1R0; -.
DR   ZFIN; ZDB-GENE-070112-1412; shq1.
DR   eggNOG; KOG3247; Eukaryota.
DR   InParanoid; A1L1R0; -.
DR   PhylomeDB; A1L1R0; -.
DR   Reactome; R-DRE-171319; Telomere Extension By Telomerase.
DR   PRO; PR:A1L1R0; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
DR   GO; GO:0005654; C:nucleoplasm; IBA:GO_Central.
DR   GO; GO:0051082; F:unfolded protein binding; IBA:GO_Central.
DR   GO; GO:0000493; P:box H/ACA snoRNP assembly; IBA:GO_Central.
DR   GO; GO:0022618; P:ribonucleoprotein complex assembly; ISS:UniProtKB.
DR   Gene3D; 2.60.40.790; -; 1.
DR   InterPro; IPR007052; CS_dom.
DR   InterPro; IPR008978; HSP20-like_chaperone.
DR   InterPro; IPR039742; Shq1.
DR   InterPro; IPR007009; Shq1_dom.
DR   PANTHER; PTHR12967; PTHR12967; 1.
DR   Pfam; PF04925; SHQ1; 1.
DR   SUPFAM; SSF49764; SSF49764; 1.
DR   PROSITE; PS51203; CS; 1.
PE   1: Evidence at protein level;
KW   Cytoplasm; Nucleus; Phosphoprotein; Reference proteome.
FT   CHAIN           1..585
FT                   /note="Protein SHQ1 homolog"
FT                   /id="PRO_0000302824"
FT   DOMAIN          1..89
FT                   /note="CS"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00547"
FT   REGION          421..461
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          495..541
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          556..585
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        427..453
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        495..540
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        561..576
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         536
FT                   /note="Phosphothreonine"
FT                   /evidence="ECO:0000269|PubMed:18307296"
FT   MOD_RES         540
FT                   /note="Phosphothreonine"
FT                   /evidence="ECO:0000269|PubMed:18307296"
SQ   SEQUENCE   585 AA;  67499 MW;  250C6B4D9C578BAE CRC64;
     MITPAFELSQ DADFLIVVIR VPYTRTSDFD IYIQEEEFKF YAKPYFLRLT LPGRIVEDGR
     EKASFDIDKG LFTLHVPKET AGQHFEGLEM LTSLLAPKGS RSAKPLVEDS EACGEGCEEE
     DEEFDWQIEQ EVYTEAPADT LKEYHKYGFG NLRSGVFSRL QEELNEVIDM KDPDNTNAEL
     RRRNRLDTET AVFCADHYLV NLYEDKEEIR NLLKFKPWWR KLNPDPSAGY DISMTFTEEE
     REQMRRFTNR SYLLDKKARF HVWLGLVDII LAYVYDVRTT EGEHNVESAW TIRKLSGTLS
     WLETYHSVQD VLVSFGRRTY CYPLYRHFSL VTLAVKDAAC IFQAGKACIL KCLLAIHKIF
     RENDPAYILN DLYITDYCIW IQRVKSKHVL ALAEPLNNAK LQKNHLELEL EIIEQAAELA
     VKEEEEKDTE SDTDDSSSSS GDSDDEDDSD EECPEKAAEK KQTAFKAHAE AVTEAFCVEL
     QRGDGRLIEE LGKRLEEELT IEEDVPQERR SASEGEGERR REHYHPHAAE SERDTTKAAT
     GKELLDVCLQ RKPLRILNTE ELDSDDDDDD DDDGDLRITV VDERG