ID   SHU1_ECOLX              Reviewed;         474 AA.
AC   P09745; Q9R2H7;
DT   01-JUL-1989, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1989, sequence version 1.
DT   25-MAY-2022, entry version 72.
DE   RecName: Full=Shufflon protein A;
OS   Escherichia coli.
OG   Plasmid IncI1 R64.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=562;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=3029698; DOI=10.1093/nar/15.3.1165;
RA   Komano T., Kubo A., Nisioka T.;
RT   "Shufflon: multi-inversion of four contiguous DNA segments of plasmid R64
RT   creates seven different open reading frames.";
RL   Nucleic Acids Res. 15:1165-1172(1987).
CC   -!- MISCELLANEOUS: This protein is expressed by a shufflon (= clustered
CC       inversion region that works as a biological switch). The orfs of this
CC       region share a constant N-terminus, while the C-terminus is variable.
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DR   EMBL; AB027308; BAA77982.1; -; Genomic_DNA.
DR   EMBL; AB027308; BAA77983.1; -; Genomic_DNA.
DR   PIR; A26421; A26421.
DR   RefSeq; WP_001389385.1; NZ_WVVK01000025.1.
DR   RefSeq; YP_003108169.1; NC_013120.1.
DR   RefSeq; YP_008998818.1; NC_023329.1.
DR   RefSeq; YP_009061391.1; NC_024977.1.
DR   RefSeq; YP_009069682.1; NC_025147.1.
DR   AlphaFoldDB; P09745; -.
DR   InterPro; IPR029017; Enolase-like_N.
DR   InterPro; IPR007001; Shufflon_N.
DR   Pfam; PF04917; Shufflon_N; 1.
DR   SUPFAM; SSF54826; SSF54826; 1.
PE   4: Predicted;
KW   Plasmid.
FT   CHAIN           1..474
FT                   /note="Shufflon protein A"
FT                   /id="PRO_0000097741"
FT   REGION          1..361
FT                   /note="Constant region"
FT   REGION          362..474
FT                   /note="Variable region"
SQ   SEQUENCE   474 AA;  49530 MW;  12FA84D73EA61104 CRC64;
     MKKYDRGWAS LETGAALLIV MLLIAWGAGI WQDYIQTKGW QTEARLVSNW TSAARSYIGK
     NYTTLQGSST TTTPAVITTT MLKNTGFLSS GFTETNSEGQ RLQAYVVRNA QNPELLQAMV
     VSSGGTPYPV KALIQMAKDI TTGLGGYIQD GKTATGALRS WSVALSNYGA KSGNGHIAVL
     LSTDELSGAA EDTDRLYRFQ VNGRPDLNKM HTAIDMGSNN LNNVGAVNAQ TGNFSGNVNG
     VNGTFSGQVK GNSGNFDVNV TAGGDIRSNN GWLITRNSKG WLNETHGGGF YMSDGSWVRS
     VNNKGIYTGG QVKGGTVRAD GRLYTGEYLQ LERTAVAGAS CSPNGLVGRD NTGAILSCQS
     GTWKTSGSLN GSYTNLGSHR GSFSGRNSGG STLFIYASGG NGGSAGGACA NTSRLQGYVG
     GTLISVNASN NPAYGKTAFI SFAVPAGTSY QITSYPTENT SCGAGVFSVF GYQT