ID   SHU2_ECOLX              Reviewed;         430 AA.
AC   P09746; Q9WWA0;
DT   01-JUL-1989, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1989, sequence version 1.
DT   25-MAY-2022, entry version 81.
DE   RecName: Full=Shufflon protein A';
OS   Escherichia coli.
OG   Plasmid IncI1 R64, and Plasmid IncI1 ColIb-P9.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=562;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   PLASMID=IncI1 R64;
RX   PubMed=3029698; DOI=10.1093/nar/15.3.1165;
RA   Komano T., Kubo A., Nisioka T.;
RT   "Shufflon: multi-inversion of four contiguous DNA segments of plasmid R64
RT   creates seven different open reading frames.";
RL   Nucleic Acids Res. 15:1165-1172(1987).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 362-430.
RC   PLASMID=IncI1 ColIb-P9;
RX   PubMed=2623084; DOI=10.1016/0147-619x(89)90029-2;
RA   Kim S.-R., Komano T.;
RT   "Cloning and nucleotide sequence of the ColIb shufflon.";
RL   Plasmid 22:180-184(1989).
CC   -!- MISCELLANEOUS: This protein is expressed by a shufflon (= clustered
CC       inversion region that works as a biological switch). The orfs of this
CC       region share a constant N-terminus, while the C-terminus is variable.
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DR   EMBL; AB027308; BAA77984.1; -; Genomic_DNA.
DR   EMBL; D90039; BAA14088.1; -; Genomic_DNA.
DR   PIR; B26421; B26421.
DR   RefSeq; WP_001417545.1; NZ_WVVD01000041.1.
DR   RefSeq; YP_009061647.1; NC_024979.1.
DR   AlphaFoldDB; P09746; -.
DR   InterPro; IPR029017; Enolase-like_N.
DR   InterPro; IPR007001; Shufflon_N.
DR   Pfam; PF04917; Shufflon_N; 1.
DR   SUPFAM; SSF54826; SSF54826; 1.
PE   4: Predicted;
KW   Plasmid.
FT   CHAIN           1..430
FT                   /note="Shufflon protein A'"
FT                   /id="PRO_0000097743"
FT   REGION          1..361
FT                   /note="Constant region"
FT   REGION          362..430
FT                   /note="Variable region"
SQ   SEQUENCE   430 AA;  45760 MW;  DAAFFD24AB727989 CRC64;
     MKKYDRGWAS LETGAALLIV MLLIAWGAGI WQDYIQTKGW QTEARLVSNW TSAARSYIGK
     NYTTLQGSST TTTPAVITTT MLKNTGFLSS GFTETNSEGQ RLQAYVVRNA QNPELLQAMV
     VSSGGTPYPV KALIQMAKDI TTGLGGYIQD GKTATGALRS WSVALSNYGA KSGNGHIAVL
     LSTDELSGAA EDTDRLYRFQ VNGRPDLNKM HTAIDMGSNN LNNVGAVNAQ TGNFSGNVNG
     VNGTFSGQVK GNSGNFDVNV TAGGDIRSNN GWLITRNSKG WLNETHGGGF YMSDGSWVRS
     VNNKGIYTGG QVKGGTVRAD GRLYTGEYLQ LERTAVAGAS CSPNGLVGRD NTGAILSCQS
     GTWGTIGGKL KVTQLSTTGY LGQFDFCAIA RMGNAEDAHY CQVVESPAGS RKWYKYEHKT
     GCIASCVTLN