BH034_ARATH
ID BH034_ARATH Reviewed; 320 AA.
AC Q9LTC7; Q8S3E8;
DT 16-DEC-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 25-MAY-2022, entry version 124.
DE RecName: Full=Transcription factor bHLH34;
DE AltName: Full=Basic helix-loop-helix protein 34;
DE Short=AtbHLH34;
DE Short=bHLH 34;
DE AltName: Full=Transcription factor EN 135;
DE AltName: Full=bHLH transcription factor bHLH034;
GN Name=BHLH34; Synonyms=EN135; OrderedLocusNames=At3g23210;
GN ORFNames=K14B15.12;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10819329; DOI=10.1093/dnares/7.2.131;
RA Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 3. I. Sequence
RT features of the regions of 4,504,864 bp covered by sixty P1 and TAC
RT clones.";
RL DNA Res. 7:131-135(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [MRNA] OF 30-320, TISSUE SPECIFICITY, GENE FAMILY, AND
RP NOMENCLATURE.
RC STRAIN=cv. Columbia; TISSUE=Flower;
RX PubMed=12679534; DOI=10.1093/molbev/msg088;
RA Heim M.A., Jakoby M., Werber M., Martin C., Weisshaar B., Bailey P.C.;
RT "The basic helix-loop-helix transcription factor family in plants: a
RT genome-wide study of protein structure and functional diversity.";
RL Mol. Biol. Evol. 20:735-747(2003).
RN [5]
RP GENE FAMILY.
RX PubMed=12897250; DOI=10.1105/tpc.013839;
RA Toledo-Ortiz G., Huq E., Quail P.H.;
RT "The Arabidopsis basic/helix-loop-helix transcription factor family.";
RL Plant Cell 15:1749-1770(2003).
RN [6]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=14600211; DOI=10.1105/tpc.151140;
RA Bailey P.C., Martin C., Toledo-Ortiz G., Quail P.H., Huq E., Heim M.A.,
RA Jakoby M., Werber M., Weisshaar B.;
RT "Update on the basic helix-loop-helix transcription factor gene family in
RT Arabidopsis thaliana.";
RL Plant Cell 15:2497-2502(2003).
CC -!- SUBUNIT: Homodimer. {ECO:0000305}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981}.
CC -!- TISSUE SPECIFICITY: Expressed constitutively in roots, leaves, stems,
CC and flowers. {ECO:0000269|PubMed:12679534}.
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DR EMBL; AB025608; BAA95734.1; -; Genomic_DNA.
DR EMBL; CP002686; AEE76735.1; -; Genomic_DNA.
DR EMBL; AY099674; AAM20525.1; -; mRNA.
DR EMBL; AY128853; AAM91253.1; -; mRNA.
DR EMBL; AF488573; AAM10939.1; -; mRNA.
DR RefSeq; NP_001327796.1; NM_001338621.1.
DR RefSeq; NP_188962.2; NM_113222.5.
DR AlphaFoldDB; Q9LTC7; -.
DR SMR; Q9LTC7; -.
DR BioGRID; 7231; 1.
DR IntAct; Q9LTC7; 1.
DR STRING; 3702.AT3G23210.1; -.
DR PaxDb; Q9LTC7; -.
DR EnsemblPlants; AT3G23210.1; AT3G23210.1; AT3G23210.
DR GeneID; 821899; -.
DR Gramene; AT3G23210.1; AT3G23210.1; AT3G23210.
DR KEGG; ath:AT3G23210; -.
DR Araport; AT3G23210; -.
DR TAIR; locus:2086198; AT3G23210.
DR eggNOG; ENOG502RXAH; Eukaryota.
DR HOGENOM; CLU_869720_0_0_1; -.
DR InParanoid; Q9LTC7; -.
DR OrthoDB; 1293523at2759; -.
DR PhylomeDB; Q9LTC7; -.
DR PRO; PR:Q9LTC7; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q9LTC7; baseline and differential.
DR Genevisible; Q9LTC7; AT.
DR GO; GO:0005634; C:nucleus; IDA:TAIR.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IDA:TAIR.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IPI:TAIR.
DR GO; GO:0071333; P:cellular response to glucose stimulus; IMP:TAIR.
DR GO; GO:0055072; P:iron ion homeostasis; IEA:InterPro.
DR GO; GO:0010030; P:positive regulation of seed germination; IGI:TAIR.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:TAIR.
DR Gene3D; 4.10.280.10; -; 1.
DR InterPro; IPR011598; bHLH_dom.
DR InterPro; IPR036638; HLH_DNA-bd_sf.
DR InterPro; IPR044818; ILR3-like.
DR PANTHER; PTHR46133; PTHR46133; 1.
DR Pfam; PF00010; HLH; 1.
DR SMART; SM00353; HLH; 1.
DR SUPFAM; SSF47459; SSF47459; 1.
DR PROSITE; PS50888; BHLH; 1.
PE 2: Evidence at transcript level;
KW DNA-binding; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..320
FT /note="Transcription factor bHLH34"
FT /id="PRO_0000358741"
FT DOMAIN 162..213
FT /note="bHLH"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00981"
FT REGION 299..320
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 320 AA; 35577 MW; F8E7F446A440E8C2 CRC64;
MYPSIEDDDD LLAALCFDQS NGVEDPYGYM QTNEDNIFQD FGSCGVNLMQ PQQEQFDSFN
GNLEQVCSSF RGGNNGVVYS SSIGSAQLDL AASFSGVLQQ ETHQVCGFRG QNDDSAVPHL
QQQQGQVFSG VVEINSSSSV GAVKEEFEEE CSGKRRRTGS CSKPGTKACR EKLRREKLND
KFMDLSSVLE PGRTPKTDKS AILDDAIRVV NQLRGEAHEL QETNQKLLEE IKSLKADKNE
LREEKLVLKA EKEKMEQQLK SMVVPSPGFM PSQHPAAFHS HKMAVAYPYG YYPPNMPMWS
PLPPADRDTS RDLKNLPPVA
