BH036_ARATH
ID BH036_ARATH Reviewed; 174 AA.
AC Q9FLI1;
DT 16-DEC-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 03-AUG-2022, entry version 125.
DE RecName: Full=Transcription factor bHLH36;
DE AltName: Full=Basic helix-loop-helix protein 36;
DE Short=AtbHLH36;
DE Short=bHLH 36;
DE AltName: Full=Transcription factor EN 6;
DE AltName: Full=bHLH transcription factor bHLH036;
GN Name=BHLH36; Synonyms=EN6; OrderedLocusNames=At5g51780; ORFNames=MIO24.9;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=9628582; DOI=10.1093/dnares/5.1.41;
RA Sato S., Kaneko T., Kotani H., Nakamura Y., Asamizu E., Miyajima N.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. IV. Sequence
RT features of the regions of 1,456,315 bp covered by nineteen physically
RT assigned P1 and TAC clones.";
RL DNA Res. 5:41-54(1998).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Kim C.J., Chen H., Cheuk R.F., Shinn P., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (FEB-2004) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [MRNA] OF 16-174, TISSUE SPECIFICITY, GENE FAMILY, AND
RP NOMENCLATURE.
RC STRAIN=cv. Columbia;
RX PubMed=12679534; DOI=10.1093/molbev/msg088;
RA Heim M.A., Jakoby M., Werber M., Martin C., Weisshaar B., Bailey P.C.;
RT "The basic helix-loop-helix transcription factor family in plants: a
RT genome-wide study of protein structure and functional diversity.";
RL Mol. Biol. Evol. 20:735-747(2003).
RN [5]
RP GENE FAMILY.
RX PubMed=12897250; DOI=10.1105/tpc.013839;
RA Toledo-Ortiz G., Huq E., Quail P.H.;
RT "The Arabidopsis basic/helix-loop-helix transcription factor family.";
RL Plant Cell 15:1749-1770(2003).
RN [6]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=14600211; DOI=10.1105/tpc.151140;
RA Bailey P.C., Martin C., Toledo-Ortiz G., Quail P.H., Huq E., Heim M.A.,
RA Jakoby M., Werber M., Weisshaar B.;
RT "Update on the basic helix-loop-helix transcription factor gene family in
RT Arabidopsis thaliana.";
RL Plant Cell 15:2497-2502(2003).
CC -!- SUBUNIT: Homodimer. {ECO:0000305}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981}.
CC -!- TISSUE SPECIFICITY: Expressed constitutively in roots, leaves, stems,
CC and flowers. {ECO:0000269|PubMed:12679534}.
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DR EMBL; AB010074; BAB11247.1; -; Genomic_DNA.
DR EMBL; CP002688; AED96125.1; -; Genomic_DNA.
DR EMBL; BT010952; AAR24730.1; -; mRNA.
DR EMBL; BT011640; AAS47646.1; -; mRNA.
DR EMBL; AF488575; -; NOT_ANNOTATED_CDS; mRNA.
DR RefSeq; NP_199991.1; NM_124557.4.
DR AlphaFoldDB; Q9FLI1; -.
DR SMR; Q9FLI1; -.
DR BioGRID; 20497; 5.
DR IntAct; Q9FLI1; 5.
DR STRING; 3702.AT5G51780.1; -.
DR PaxDb; Q9FLI1; -.
DR PRIDE; Q9FLI1; -.
DR EnsemblPlants; AT5G51780.1; AT5G51780.1; AT5G51780.
DR GeneID; 835252; -.
DR Gramene; AT5G51780.1; AT5G51780.1; AT5G51780.
DR KEGG; ath:AT5G51780; -.
DR Araport; AT5G51780; -.
DR TAIR; locus:2165311; AT5G51780.
DR eggNOG; ENOG502S1BU; Eukaryota.
DR HOGENOM; CLU_094733_1_1_1; -.
DR InParanoid; Q9FLI1; -.
DR PhylomeDB; Q9FLI1; -.
DR PRO; PR:Q9FLI1; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9FLI1; baseline and differential.
DR GO; GO:0090575; C:RNA polymerase II transcription regulator complex; IBA:GO_Central.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0000977; F:RNA polymerase II transcription regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:TAIR.
DR Gene3D; 4.10.280.10; -; 1.
DR InterPro; IPR011598; bHLH_dom.
DR InterPro; IPR036638; HLH_DNA-bd_sf.
DR InterPro; IPR015660; MASH1/Ascl1a-like.
DR PANTHER; PTHR13935; PTHR13935; 1.
DR Pfam; PF00010; HLH; 1.
DR SMART; SM00353; HLH; 1.
DR SUPFAM; SSF47459; SSF47459; 1.
DR PROSITE; PS50888; BHLH; 1.
PE 2: Evidence at transcript level;
KW DNA-binding; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..174
FT /note="Transcription factor bHLH36"
FT /id="PRO_0000358743"
FT DOMAIN 1..53
FT /note="bHLH"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00981"
FT CONFLICT 135
FT /note="L -> F (in Ref. 4; AF488575)"
FT /evidence="ECO:0000305"
FT CONFLICT 165
FT /note="E -> G (in Ref. 4; AF488575)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 174 AA; 19929 MW; 63EF8143EEEE090A CRC64;
MEKMMHRETE RQRRQEMASL YASLRSLLPL HFIKGKRSTS DQVNEAVNYI KYLQRKIKEL
SVRRDDLMVL SRGSLLGSSN GDFKEDVEMI SGKNHVVVRQ CLVGVEIMLS SRCCGGQPRF
SSVLQVLSEY GLCLLNSISS IVDDRLVYTI QAEVNDMALM IDLAELEKRL IRMK
