ID   BH041_ARATH             Reviewed;         466 AA.
AC   Q9LTS4;
DT   16-DEC-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   25-MAY-2022, entry version 113.
DE   RecName: Full=Putative transcription factor bHLH041;
DE   AltName: Full=Basic helix-loop-helix protein 41;
DE            Short=AtbHLH41;
DE            Short=bHLH 41;
DE   AltName: Full=Transcription factor EN 51;
DE   AltName: Full=bHLH transcription factor bHLH041;
GN   Name=BHLH41; Synonyms=EN51; OrderedLocusNames=At5g56960; ORFNames=MHM17.7;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10718197; DOI=10.1093/dnares/7.1.31;
RA   Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Kotani H.,
RA   Tabata S.;
RT   "Structural analysis of Arabidopsis thaliana chromosome 5. X. Sequence
RT   features of the regions of 3,076,755 bp covered by sixty P1 and TAC
RT   clones.";
RL   DNA Res. 7:31-63(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=12679534; DOI=10.1093/molbev/msg088;
RA   Heim M.A., Jakoby M., Werber M., Martin C., Weisshaar B., Bailey P.C.;
RT   "The basic helix-loop-helix transcription factor family in plants: a
RT   genome-wide study of protein structure and functional diversity.";
RL   Mol. Biol. Evol. 20:735-747(2003).
RN   [4]
RP   GENE FAMILY.
RX   PubMed=12897250; DOI=10.1105/tpc.013839;
RA   Toledo-Ortiz G., Huq E., Quail P.H.;
RT   "The Arabidopsis basic/helix-loop-helix transcription factor family.";
RL   Plant Cell 15:1749-1770(2003).
RN   [5]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=14600211; DOI=10.1105/tpc.151140;
RA   Bailey P.C., Martin C., Toledo-Ortiz G., Quail P.H., Huq E., Heim M.A.,
RA   Jakoby M., Werber M., Weisshaar B.;
RT   "Update on the basic helix-loop-helix transcription factor gene family in
RT   Arabidopsis thaliana.";
RL   Plant Cell 15:2497-2502(2003).
CC   -!- SUBUNIT: Homodimer. {ECO:0000305}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981}.
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DR   EMBL; AB024035; BAA97026.1; -; Genomic_DNA.
DR   EMBL; CP002688; AED96827.1; -; Genomic_DNA.
DR   RefSeq; NP_200506.1; NM_125078.2.
DR   AlphaFoldDB; Q9LTS4; -.
DR   SMR; Q9LTS4; -.
DR   STRING; 3702.AT5G56960.1; -.
DR   iPTMnet; Q9LTS4; -.
DR   PaxDb; Q9LTS4; -.
DR   PRIDE; Q9LTS4; -.
DR   EnsemblPlants; AT5G56960.1; AT5G56960.1; AT5G56960.
DR   GeneID; 835798; -.
DR   Gramene; AT5G56960.1; AT5G56960.1; AT5G56960.
DR   KEGG; ath:AT5G56960; -.
DR   Araport; AT5G56960; -.
DR   TAIR; locus:2164605; AT5G56960.
DR   eggNOG; ENOG502QUVA; Eukaryota.
DR   HOGENOM; CLU_024717_1_1_1; -.
DR   InParanoid; Q9LTS4; -.
DR   PhylomeDB; Q9LTS4; -.
DR   PRO; PR:Q9LTS4; -.
DR   Proteomes; UP000006548; Chromosome 5.
DR   ExpressionAtlas; Q9LTS4; baseline and differential.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR   GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:TAIR.
DR   CDD; cd11393; bHLH_AtbHLH_like; 1.
DR   Gene3D; 4.10.280.10; -; 1.
DR   InterPro; IPR044658; bHLH92/bHLH041-like.
DR   InterPro; IPR045239; bHLH95_bHLH.
DR   InterPro; IPR011598; bHLH_dom.
DR   InterPro; IPR036638; HLH_DNA-bd_sf.
DR   PANTHER; PTHR46665; PTHR46665; 1.
DR   Pfam; PF00010; HLH; 1.
DR   SMART; SM00353; HLH; 1.
DR   SUPFAM; SSF47459; SSF47459; 1.
DR   PROSITE; PS50888; BHLH; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Nucleus; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..466
FT                   /note="Putative transcription factor bHLH041"
FT                   /id="PRO_0000358744"
FT   DOMAIN          285..334
FT                   /note="bHLH"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00981"
FT   REGION          108..129
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          194..213
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          260..289
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        194..211
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   466 AA;  52745 MW;  3878B6D4DF5513FA CRC64;
     MMHLILSCSY LISMDGYYNE ASEEPSSSSS SGSLARSLFH EYRQSVIPLQ NGHVPSMAFM
     NNLPYVEIRP QESQRLAFND TQRLFYQMKI EASLREWFPE DFNRKSSPAN SDYLRPPHYP
     SSSSSSLSPN NISEYSSLLF PLIPKPSTTT EAVNVPVLPP LAPINMIHPQ HQEPLFRNRQ
     REEEAMTQAI LAVLTGPSSP PSTSSSPQRK GRATAFKRYY SMISDRGRAP LPSVRKQSMM
     TRAMSFYNRL NINQRERFTR ENATTHGEGS GGSGGGGRYT SGPSATQLQH MISERKRREK
     LNESFQALRS LLPPGTKKDK ASVLSIAREQ LSSLQGEISK LLERNREVEA KLAGEREIEN
     DLRPEERFNV RIRHIPESTS RERTLDLRVV LRGDIIRVDD LMIRLLEFLK QINNVSLVSI
     EARTLARAEG DTSIVLVISL RLKIEGEWDE SAFQEAVRRV VADLAH