BH051_ARATH
ID BH051_ARATH Reviewed; 254 AA.
AC Q9XEF0;
DT 16-DEC-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1999, sequence version 1.
DT 03-AUG-2022, entry version 126.
DE RecName: Full=Transcription factor bHLH51;
DE AltName: Full=Basic helix-loop-helix protein 51;
DE Short=AtbHLH51;
DE Short=bHLH 51;
DE AltName: Full=Transcription factor EN 57;
DE AltName: Full=bHLH transcription factor bHLH051;
GN Name=BHLH51; Synonyms=EN57; OrderedLocusNames=At2g40200; ORFNames=T7M7.8;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=10207155;
RA Wang M.L., Belmonte S., Kim U., Dolan M., Morris J.W., Goodman H.M.;
RT "A cluster of ABA-regulated genes on Arabidopsis thaliana BAC T07M07.";
RL Genome Res. 9:325-333(1999).
RN [2]
RP NUCLEOTIDE SEQUENCE [MRNA], TISSUE SPECIFICITY, INDUCTION, GENE FAMILY, AND
RP NOMENCLATURE.
RC STRAIN=cv. Columbia;
RX PubMed=12679534; DOI=10.1093/molbev/msg088;
RA Heim M.A., Jakoby M., Werber M., Martin C., Weisshaar B., Bailey P.C.;
RT "The basic helix-loop-helix transcription factor family in plants: a
RT genome-wide study of protein structure and functional diversity.";
RL Mol. Biol. Evol. 20:735-747(2003).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Bautista V.R., Kim C.J., Chen H., Wu S.Y., De Los Reyes C., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (JAN-2007) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP GENE FAMILY.
RX PubMed=12897250; DOI=10.1105/tpc.013839;
RA Toledo-Ortiz G., Huq E., Quail P.H.;
RT "The Arabidopsis basic/helix-loop-helix transcription factor family.";
RL Plant Cell 15:1749-1770(2003).
RN [7]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=14600211; DOI=10.1105/tpc.151140;
RA Bailey P.C., Martin C., Toledo-Ortiz G., Quail P.H., Huq E., Heim M.A.,
RA Jakoby M., Werber M., Weisshaar B.;
RT "Update on the basic helix-loop-helix transcription factor gene family in
RT Arabidopsis thaliana.";
RL Plant Cell 15:2497-2502(2003).
CC -!- SUBUNIT: Homodimer. {ECO:0000305}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981}.
CC -!- TISSUE SPECIFICITY: Expressed constitutively in roots, stems, and
CC flowers. {ECO:0000269|PubMed:12679534}.
CC -!- INDUCTION: Repressed by salicylic acid (SA) treatment.
CC {ECO:0000269|PubMed:12679534}.
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DR EMBL; AF085279; AAD25935.1; -; Genomic_DNA.
DR EMBL; AF488586; AAM10943.1; -; mRNA.
DR EMBL; CP002685; AEC09795.1; -; Genomic_DNA.
DR EMBL; BT029997; ABN04735.1; -; mRNA.
DR EMBL; BT030051; ABN04789.1; -; mRNA.
DR PIR; E84826; E84826.
DR RefSeq; NP_181549.1; NM_129578.4.
DR AlphaFoldDB; Q9XEF0; -.
DR SMR; Q9XEF0; -.
DR BioGRID; 3949; 2.
DR IntAct; Q9XEF0; 2.
DR STRING; 3702.AT2G40200.1; -.
DR PaxDb; Q9XEF0; -.
DR PRIDE; Q9XEF0; -.
DR ProteomicsDB; 240769; -.
DR EnsemblPlants; AT2G40200.1; AT2G40200.1; AT2G40200.
DR GeneID; 818611; -.
DR Gramene; AT2G40200.1; AT2G40200.1; AT2G40200.
DR KEGG; ath:AT2G40200; -.
DR Araport; AT2G40200; -.
DR TAIR; locus:2065086; AT2G40200.
DR eggNOG; ENOG502RDXR; Eukaryota.
DR HOGENOM; CLU_063967_2_1_1; -.
DR InParanoid; Q9XEF0; -.
DR OMA; SKAFMVP; -.
DR OrthoDB; 1271103at2759; -.
DR PhylomeDB; Q9XEF0; -.
DR PRO; PR:Q9XEF0; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q9XEF0; baseline and differential.
DR Genevisible; Q9XEF0; AT.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:TAIR.
DR Gene3D; 4.10.280.10; -; 1.
DR InterPro; IPR045847; AIG1-like.
DR InterPro; IPR011598; bHLH_dom.
DR InterPro; IPR036638; HLH_DNA-bd_sf.
DR PANTHER; PTHR45844; PTHR45844; 1.
DR Pfam; PF00010; HLH; 1.
DR SMART; SM00353; HLH; 1.
DR SUPFAM; SSF47459; SSF47459; 1.
DR PROSITE; PS50888; BHLH; 1.
PE 2: Evidence at transcript level;
KW DNA-binding; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..254
FT /note="Transcription factor bHLH51"
FT /id="PRO_0000358748"
FT DOMAIN 62..111
FT /note="bHLH"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00981"
SQ SEQUENCE 254 AA; 28415 MW; EE3BCE353EE52619 CRC64;
MENSYDSSKW SDSTTPYMVS WSLQSESSDS DWNRFNLGFS SSSFGGNFPA DDCVGGIEKA
ESLSRSHRLA EKRRRDRINS HLTALRKLVP NSDKLDKAAL LATVIEQVKE LKQKAAESPI
FQDLPTEADE VTVQPETISD FESNTNTIIF KASFCCEDQP EAISEIIRVL TKLQLETIQA
EIISVGGRMR INFILKDSNC NETTNIAASA KALKQSLCSA LNRITSSSTT TSSVCRIRSK
RQRWFLSSHY SHNE
