BH055_ARATH
ID BH055_ARATH Reviewed; 257 AA.
AC Q9LN95; Q9LN89;
DT 16-DEC-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 03-AUG-2022, entry version 118.
DE RecName: Full=Transcription factor bHLH55;
DE AltName: Full=Basic helix-loop-helix protein 55;
DE Short=AtbHLH55;
DE Short=bHLH 55;
DE AltName: Full=Transcription factor EN 1;
DE AltName: Full=bHLH transcription factor bHLH055;
GN Name=BHLH55; Synonyms=EN1; OrderedLocusNames=At1g12540;
GN ORFNames=F5O11.28, T12C24.8;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [MRNA] OF 75-257, TISSUE SPECIFICITY, INDUCTION BY SA,
RP GENE FAMILY, AND NOMENCLATURE.
RC STRAIN=cv. Columbia; TISSUE=Root;
RX PubMed=12679534; DOI=10.1093/molbev/msg088;
RA Heim M.A., Jakoby M., Werber M., Martin C., Weisshaar B., Bailey P.C.;
RT "The basic helix-loop-helix transcription factor family in plants: a
RT genome-wide study of protein structure and functional diversity.";
RL Mol. Biol. Evol. 20:735-747(2003).
RN [4]
RP GENE FAMILY.
RX PubMed=12897250; DOI=10.1105/tpc.013839;
RA Toledo-Ortiz G., Huq E., Quail P.H.;
RT "The Arabidopsis basic/helix-loop-helix transcription factor family.";
RL Plant Cell 15:1749-1770(2003).
RN [5]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=14600211; DOI=10.1105/tpc.151140;
RA Bailey P.C., Martin C., Toledo-Ortiz G., Quail P.H., Huq E., Heim M.A.,
RA Jakoby M., Werber M., Weisshaar B.;
RT "Update on the basic helix-loop-helix transcription factor gene family in
RT Arabidopsis thaliana.";
RL Plant Cell 15:2497-2502(2003).
CC -!- SUBUNIT: Homodimer. {ECO:0000305}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981}.
CC -!- TISSUE SPECIFICITY: Expressed in roots, leaves, stems, and flowers.
CC {ECO:0000269|PubMed:12679534}.
CC -!- INDUCTION: By salicylic acid (SA). {ECO:0000269|PubMed:12679534}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAF88076.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AC025416; AAF79643.1; -; Genomic_DNA.
DR EMBL; AC025417; AAF88076.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002684; AEE28895.1; -; Genomic_DNA.
DR EMBL; AF488589; -; NOT_ANNOTATED_CDS; mRNA.
DR PIR; E86259; E86259.
DR RefSeq; NP_172715.4; NM_101125.5.
DR AlphaFoldDB; Q9LN95; -.
DR SMR; Q9LN95; -.
DR STRING; 3702.AT1G12540.1; -.
DR PaxDb; Q9LN95; -.
DR PRIDE; Q9LN95; -.
DR EnsemblPlants; AT1G12540.1; AT1G12540.1; AT1G12540.
DR GeneID; 837810; -.
DR Gramene; AT1G12540.1; AT1G12540.1; AT1G12540.
DR KEGG; ath:AT1G12540; -.
DR Araport; AT1G12540; -.
DR TAIR; locus:2034750; AT1G12540.
DR eggNOG; ENOG502S1BU; Eukaryota.
DR HOGENOM; CLU_094733_0_0_1; -.
DR InParanoid; Q9LN95; -.
DR OMA; NIVSCIS; -.
DR OrthoDB; 1275123at2759; -.
DR PhylomeDB; Q9LN95; -.
DR PRO; PR:Q9LN95; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9LN95; baseline and differential.
DR GO; GO:0090575; C:RNA polymerase II transcription regulator complex; IBA:GO_Central.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0000977; F:RNA polymerase II transcription regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR Gene3D; 4.10.280.10; -; 1.
DR InterPro; IPR011598; bHLH_dom.
DR InterPro; IPR036638; HLH_DNA-bd_sf.
DR InterPro; IPR015660; MASH1/Ascl1a-like.
DR PANTHER; PTHR13935; PTHR13935; 1.
DR Pfam; PF00010; HLH; 1.
DR SMART; SM00353; HLH; 1.
DR SUPFAM; SSF47459; SSF47459; 1.
DR PROSITE; PS50888; BHLH; 1.
PE 2: Evidence at transcript level;
KW DNA-binding; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..257
FT /note="Transcription factor bHLH55"
FT /id="PRO_0000358752"
FT DOMAIN 74..126
FT /note="bHLH"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00981"
SQ SEQUENCE 257 AA; 29100 MW; DA15F18145485BBA CRC64;
MNFPDSSLFT PNFAYENDLD FSSLITPSTR VSFQEPKPCN PVIHSAGIEN DGRQNCETTM
TLSEIMKGDD EPKNKRAKHK ELERQRRQEN TSLFKILRYL LPSQYIKGKR SSADHVLEAV
NYIKDLQKKI KEVSEKRDRI KRSITHPSSR GEFSIRSLAS STCSCVGDTN IAVVVRPCLI
GLEIVVSCCN RHESCLSSVL QLLAQEQCFN IVSCISTRLH QGFIHTIASE VEEGIEVYFS
ELQEKIIKIG TSRVTTR
