BH071_ARATH
ID BH071_ARATH Reviewed; 327 AA.
AC Q56XR0; Q8LB18; Q9FIQ6;
DT 16-DEC-2008, integrated into UniProtKB/Swiss-Prot.
DT 10-MAY-2005, sequence version 1.
DT 25-MAY-2022, entry version 112.
DE RecName: Full=Transcription factor bHLH71;
DE AltName: Full=Basic helix-loop-helix protein 71;
DE Short=AtbHLH71;
DE Short=bHLH 71;
DE AltName: Full=Transcription factor EN 17;
DE AltName: Full=bHLH transcription factor bHLH071;
GN Name=BHLH71; Synonyms=EN17; OrderedLocusNames=At5g46690; ORFNames=MZA15.10;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10048488; DOI=10.1093/dnares/5.6.379;
RA Asamizu E., Sato S., Kaneko T., Nakamura Y., Kotani H., Miyajima N.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. VIII. Sequence
RT features of the regions of 1,081,958 bp covered by seventeen physically
RT assigned P1 and TAC clones.";
RL DNA Res. 5:379-391(1998).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Shinn P., Chen H., Kim C.J., Quinitio C., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP NUCLEOTIDE SEQUENCE [MRNA] OF 121-327, TISSUE SPECIFICITY, GENE FAMILY, AND
RP NOMENCLATURE.
RC STRAIN=cv. Columbia; TISSUE=Flower;
RX PubMed=12679534; DOI=10.1093/molbev/msg088;
RA Heim M.A., Jakoby M., Werber M., Martin C., Weisshaar B., Bailey P.C.;
RT "The basic helix-loop-helix transcription factor family in plants: a
RT genome-wide study of protein structure and functional diversity.";
RL Mol. Biol. Evol. 20:735-747(2003).
RN [7]
RP GENE FAMILY.
RX PubMed=12897250; DOI=10.1105/tpc.013839;
RA Toledo-Ortiz G., Huq E., Quail P.H.;
RT "The Arabidopsis basic/helix-loop-helix transcription factor family.";
RL Plant Cell 15:1749-1770(2003).
RN [8]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=14600211; DOI=10.1105/tpc.151140;
RA Bailey P.C., Martin C., Toledo-Ortiz G., Quail P.H., Huq E., Heim M.A.,
RA Jakoby M., Werber M., Weisshaar B.;
RT "Update on the basic helix-loop-helix transcription factor gene family in
RT Arabidopsis thaliana.";
RL Plant Cell 15:2497-2502(2003).
RN [9]
RP FUNCTION, INTERACTION WITH FAMA, AND TISSUE SPECIFICITY.
RX PubMed=17088607; DOI=10.1105/tpc.106.046136;
RA Ohashi-Ito K., Bergmann D.C.;
RT "Arabidopsis FAMA controls the final proliferation/differentiation switch
RT during stomatal development.";
RL Plant Cell 18:2493-2505(2006).
CC -!- FUNCTION: Transcription factor. May be involved in the differentiation
CC of stomatal guard cells. {ECO:0000269|PubMed:17088607}.
CC -!- SUBUNIT: Homodimer (Probable). Interacts with FAMA.
CC {ECO:0000269|PubMed:17088607, ECO:0000305}.
CC -!- INTERACTION:
CC Q56XR0; Q0V7X4: FIT; NbExp=3; IntAct=EBI-4432361, EBI-1640543;
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- TISSUE SPECIFICITY: Expressed in leaves, stems, and flowers.
CC {ECO:0000269|PubMed:12679534, ECO:0000269|PubMed:17088607}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAB08913.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AB016882; BAB08913.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002688; AED95414.1; -; Genomic_DNA.
DR EMBL; AK221613; BAD95200.1; -; mRNA.
DR EMBL; BT025663; ABF74724.1; -; mRNA.
DR EMBL; AY087479; AAM65023.1; -; mRNA.
DR EMBL; AF488603; -; NOT_ANNOTATED_CDS; mRNA.
DR RefSeq; NP_001331893.1; NM_001344694.1.
DR RefSeq; NP_568666.1; NM_124039.3.
DR AlphaFoldDB; Q56XR0; -.
DR SMR; Q56XR0; -.
DR BioGRID; 19960; 7.
DR IntAct; Q56XR0; 7.
DR STRING; 3702.AT5G46690.1; -.
DR PaxDb; Q56XR0; -.
DR PRIDE; Q56XR0; -.
DR EnsemblPlants; AT5G46690.1; AT5G46690.1; AT5G46690.
DR GeneID; 834712; -.
DR Gramene; AT5G46690.1; AT5G46690.1; AT5G46690.
DR KEGG; ath:AT5G46690; -.
DR Araport; AT5G46690; -.
DR TAIR; locus:2178560; AT5G46690.
DR eggNOG; ENOG502QTSP; Eukaryota.
DR HOGENOM; CLU_044652_4_0_1; -.
DR InParanoid; Q56XR0; -.
DR OMA; CMESTTT; -.
DR OrthoDB; 1047722at2759; -.
DR PhylomeDB; Q56XR0; -.
DR PRO; PR:Q56XR0; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q56XR0; baseline and differential.
DR Genevisible; Q56XR0; AT.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:TAIR.
DR Gene3D; 4.10.280.10; -; 1.
DR InterPro; IPR011598; bHLH_dom.
DR InterPro; IPR036638; HLH_DNA-bd_sf.
DR Pfam; PF00010; HLH; 1.
DR SMART; SM00353; HLH; 1.
DR SUPFAM; SSF47459; SSF47459; 1.
DR PROSITE; PS50888; BHLH; 1.
PE 1: Evidence at protein level;
KW Developmental protein; DNA-binding; Nucleus; Reference proteome;
KW Transcription; Transcription regulation.
FT CHAIN 1..327
FT /note="Transcription factor bHLH71"
FT /id="PRO_0000358765"
FT DOMAIN 85..136
FT /note="bHLH"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00981"
FT REGION 46..88
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 151..176
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 51
FT /note="N -> H (in Ref. 5; AAM65023)"
FT /evidence="ECO:0000305"
FT CONFLICT 65
FT /note="R -> Q (in Ref. 5; AAM65023)"
FT /evidence="ECO:0000305"
FT CONFLICT 165
FT /note="S -> T (in Ref. 5; AAM65023)"
FT /evidence="ECO:0000305"
FT CONFLICT 314
FT /note="F -> L (in Ref. 6; AF488603)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 327 AA; 36647 MW; 9B4884DDD4304761 CRC64;
MTLEALSSNG LLNFLLSETL SPTPFKSLVD LEPLPENDVI ISKNTISEIS NQEPPPQRQP
PATNRGKKRR RRKPRVCKNE EEAENQRMTH IAVERNRRRQ MNQHLSVLRS LMPQPFAHKG
DQASIVGGAI DFIKELEHKL LSLEAQKHHN AKLNQSVTSS TSQDSNGEQE NPHQPSSLSL
SQFFLHSYDP SQENRNGSTS SVKTPMEDLE VTLIETHANI RILSRRRGFR WSTLATTKPP
QLSKLVASLQ SLSLSILHLS VTTLDNYAIY SISAKVEESC QLSSVDDIAG AVHHMLSIIE
EEPFCCSSMS ELPFDFSLNH SNVTHSL
