ID   SID5_AJECA              Reviewed;         136 AA.
AC   B2KWI4;
DT   20-JUN-2018, integrated into UniProtKB/Swiss-Prot.
DT   10-JUN-2008, sequence version 1.
DT   25-MAY-2022, entry version 18.
DE   RecName: Full=Probable acyltransferase SID5 {ECO:0000303|PubMed:18404210};
DE            EC=2.3.1.- {ECO:0000305|PubMed:18404210};
DE   AltName: Full=Siderophore biosynthesis cluster protein SID5 {ECO:0000303|PubMed:18404210};
GN   Name=SID5 {ECO:0000303|PubMed:18404210};
OS   Ajellomyces capsulatus (Darling's disease fungus) (Histoplasma capsulatum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Ajellomycetaceae; Histoplasma.
OX   NCBI_TaxID=5037;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND FUNCTION.
RC   STRAIN=ATCC 26032 / G217B;
RX   PubMed=18404210; DOI=10.1371/journal.ppat.1000044;
RA   Hwang L.H., Mayfield J.A., Rine J., Sil A.;
RT   "Histoplasma requires SID1, a member of an iron-regulated siderophore gene
RT   cluster, for host colonization.";
RL   PLoS Pathog. 4:E1000044-E1000044(2008).
CC   -!- FUNCTION: Probable acyltransferase; part of the gene cluster that
CC       mediates the biosynthesis of hydroxamate-containing siderophores that
CC       play a critical role in virulence via intracellular iron acquisition
CC       during macrophage infection (PubMed:18404210).
CC       {ECO:0000269|PubMed:18404210}.
CC   -!- PATHWAY: Siderophore biosynthesis. {ECO:0000305|PubMed:18404210}.
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DR   EMBL; EU253979; ACC64457.1; -; Genomic_DNA.
DR   AlphaFoldDB; B2KWI4; -.
DR   GO; GO:0016746; F:acyltransferase activity; IEA:UniProtKB-KW.
DR   InterPro; IPR016181; Acyl_CoA_acyltransferase.
DR   SUPFAM; SSF55729; SSF55729; 1.
PE   4: Predicted;
KW   Acyltransferase; Transferase.
FT   CHAIN           1..136
FT                   /note="Probable acyltransferase SID5"
FT                   /id="PRO_0000444412"
SQ   SEQUENCE   136 AA;  15116 MW;  2F76401FC06B77C0 CRC64;
     MTVWEVHWRG EADGWQKNPT VAWLQGPEKE GAEKAFWAIW EVGDKLLNHR SAPGAPKKRG
     IGQLLIDWGL DVGEKLQVPV YLESTRAGLV FYTKLGFEKL SQGAVVKAEV THVASDFELP
     VTVKMPSAAR RMGFEG