ID   SIDA_CAUVN              Reviewed;          29 AA.
AC   B8GWS7;
DT   28-NOV-2012, integrated into UniProtKB/Swiss-Prot.
DT   28-NOV-2012, sequence version 2.
DT   25-MAY-2022, entry version 38.
DE   RecName: Full=Cell division inhibitor SidA;
DE   AltName: Full=SOS-induced inhibitor of cell division A;
GN   Name=sidA; OrderedLocusNames=CCNA_02004;
OS   Caulobacter vibrioides (strain NA1000 / CB15N) (Caulobacter crescentus).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Caulobacterales;
OC   Caulobacteraceae; Caulobacter.
OX   NCBI_TaxID=565050;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NA1000 / CB15N;
RX   PubMed=20472802; DOI=10.1128/jb.00255-10;
RA   Marks M.E., Castro-Rojas C.M., Teiling C., Du L., Kapatral V.,
RA   Walunas T.L., Crosson S.;
RT   "The genetic basis of laboratory adaptation in Caulobacter crescentus.";
RL   J. Bacteriol. 192:3678-3688(2010).
RN   [2]
RP   FUNCTION, INTERACTION WITH FTSW AND FTSN, SUBCELLULAR LOCATION, INDUCTION,
RP   IDENTIFICATION OF START SITE, AND GENE NAME.
RC   STRAIN=NA1000 / CB15N;
RX   PubMed=21685367; DOI=10.1101/gad.2038911;
RA   Modell J.W., Hopkins A.C., Laub M.T.;
RT   "A DNA damage checkpoint in Caulobacter crescentus inhibits cell division
RT   through a direct interaction with FtsW.";
RL   Genes Dev. 25:1328-1343(2011).
CC   -!- FUNCTION: Inhibits cell division by binding directly to FtsW to prevent
CC       the final constriction of the FtsZ ring. {ECO:0000269|PubMed:21685367}.
CC   -!- SUBUNIT: Interacts strongly with FtsW and to a lesser extent with FtsN.
CC       {ECO:0000269|PubMed:21685367}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane
CC       {ECO:0000269|PubMed:21685367}; Single-pass membrane protein
CC       {ECO:0000269|PubMed:21685367}.
CC   -!- INDUCTION: Induced in response to DNA damage.
CC       {ECO:0000269|PubMed:21685367}.
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DR   EMBL; CP001340; ACL95469.2; -; Genomic_DNA.
DR   RefSeq; WP_024265750.1; NC_011916.1.
DR   RefSeq; YP_002517377.2; NC_011916.1.
DR   AlphaFoldDB; B8GWS7; -.
DR   DIP; DIP-61064N; -.
DR   IntAct; B8GWS7; 2.
DR   EnsemblBacteria; ACL95469; ACL95469; CCNA_02004.
DR   GeneID; 7333332; -.
DR   KEGG; ccs:CCNA_02004; -.
DR   PATRIC; fig|565050.3.peg.1963; -.
DR   HOGENOM; CLU_219332_0_0_5; -.
DR   Proteomes; UP000001364; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IDA:UniProtKB.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IDA:UniProtKB.
DR   GO; GO:0051782; P:negative regulation of cell division; IDA:UniProtKB.
PE   1: Evidence at protein level;
KW   Cell cycle; Cell division; Cell inner membrane; Cell membrane; Membrane;
KW   Reference proteome; Stress response; Transmembrane; Transmembrane helix.
FT   CHAIN           1..29
FT                   /note="Cell division inhibitor SidA"
FT                   /id="PRO_0000420267"
FT   TRANSMEM        9..29
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   29 AA;  3215 MW;  31D881CE0F58DB53 CRC64;
     MIRVARESFA LVSVIGFVWM MCTVANLVA