ID   SIEB_BPP22              Reviewed;         192 AA.
AC   P38396; Q7PCF4;
DT   01-OCT-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1994, sequence version 1.
DT   12-AUG-2020, entry version 67.
DE   RecName: Full=Superinfection exclusion protein B;
GN   Name=sieB; Synonyms=git;
OS   Salmonella phage P22 (Bacteriophage P22).
OC   Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC   Caudovirales; Podoviridae; Lederbergvirus.
OX   NCBI_TaxID=10754;
OH   NCBI_TaxID=90371; Salmonella typhimurium.
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=8335629; DOI=10.1128/jb.175.15.4712-4718.1993;
RA   Ranade K., Poteete A.R.;
RT   "Superinfection exclusion (sieB) genes of bacteriophages P22 and lambda.";
RL   J. Bacteriol. 175:4712-4718(1993).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=11053393; DOI=10.1128/jb.182.22.6472-6481.2000;
RA   Vander Byl C.S., Kropinski A.M.B.;
RT   "Sequence of the genome of Salmonella bacteriophage P22.";
RL   J. Bacteriol. 182:6472-6481(2000).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=12562822; DOI=10.1128/jb.185.4.1475-1477.2003;
RA   Pedulla M.L., Ford M.E., Karthikeyan T., Houtz J.M., Hendrix R.W.,
RA   Hatfull G.F., Poteete A.R., Gilcrease E.B., Winn-Stapley D.A.,
RA   Casjens S.R.;
RT   "Corrected sequence of the bacteriophage P22 genome.";
RL   J. Bacteriol. 185:1475-1477(2003).
CC   -!- FUNCTION: Has a role in the prevention of superinfection by phages that
CC       are insensitive to repression.
CC   -!- SUBCELLULAR LOCATION: Host membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; L18800; AAA72007.1; -; Unassigned_DNA.
DR   EMBL; AF217253; AAF75022.1; -; Genomic_DNA.
DR   EMBL; BK000583; DAA01019.1; -; Genomic_DNA.
DR   PIR; A40606; A40606.
DR   RefSeq; NP_059604.1; NC_002371.2.
DR   GeneID; 1262810; -.
DR   KEGG; vg:1262810; -.
DR   Proteomes; UP000001795; Genome.
DR   Proteomes; UP000007960; Genome.
DR   GO; GO:0033644; C:host cell membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR025982; SieB.
DR   Pfam; PF14163; SieB; 1.
PE   4: Predicted;
KW   Host membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..192
FT                   /note="Superinfection exclusion protein B"
FT                   /id="PRO_0000077739"
FT   TRANSMEM        22..42
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        51..71
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   192 AA;  22443 MW;  D05756ED45649925 CRC64;
     MNNSWWQELM RFFLQGMTLK QLIHMLIILI VLIIVMPVSV KEWINLHNPE ILPHYWMYYI
     LLFCVSYVLN GVVNSVYHAV TERIEASTAQ RRKDREEKVV RDLFDSLTLG ERAYLAFAVA
     ANNQLKTEKG SPEAISLLKK GIITRLPSAI GYPDIDRFII PEKYFNECYM RFAGKSDILM
     NELIVQDEQL KK