ID   SIEB_LAMBD              Reviewed;         184 AA.
AC   P03762;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   13-JUL-2010, sequence version 2.
DT   12-AUG-2020, entry version 72.
DE   RecName: Full=Superinfection exclusion protein B;
GN   Name=sieB; Synonyms=git;
OS   Escherichia phage lambda (Bacteriophage lambda).
OC   Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC   Caudovirales; Siphoviridae; Lambdavirus.
OX   NCBI_TaxID=10710;
OH   NCBI_TaxID=562; Escherichia coli.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=6221115; DOI=10.1016/0022-2836(82)90546-0;
RA   Sanger F., Coulson A.R., Hong G.F., Hill D.F., Petersen G.B.;
RT   "Nucleotide sequence of bacteriophage lambda DNA.";
RL   J. Mol. Biol. 162:729-773(1982).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=6458018; DOI=10.1093/nar/9.18.4639;
RA   Ineichen K., Shepherd J.C.W., Bickle T.A.;
RT   "The DNA sequence of the phage lambda genome between PL and the gene bet.";
RL   Nucleic Acids Res. 9:4639-4653(1981).
RN   [3]
RP   IDENTIFICATION.
RX   PubMed=8335629; DOI=10.1128/jb.175.15.4712-4718.1993;
RA   Ranade K., Poteete A.R.;
RT   "Superinfection exclusion (sieB) genes of bacteriophages P22 and lambda.";
RL   J. Bacteriol. 175:4712-4718(1993).
CC   -!- FUNCTION: Has a role in the prevention of superinfection by phages that
CC       are insensitive to repression.
CC   -!- SUBCELLULAR LOCATION: Host membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- CAUTION: It is uncertain whether Met-1, Met-2 or Met-6 is the
CC       initiator. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CAA23982.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; J02459; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; V00638; CAA23982.1; ALT_INIT; Genomic_DNA.
DR   PIR; I43010; QQBPGL.
DR   RefSeq; NP_597779.1; NC_001416.1.
DR   IntAct; P03762; 3.
DR   GeneID; 2703531; -.
DR   KEGG; vg:2703531; -.
DR   Proteomes; UP000001711; Genome.
DR   GO; GO:0033644; C:host cell membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR025982; SieB.
DR   Pfam; PF14163; SieB; 1.
PE   4: Predicted;
KW   Host membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..184
FT                   /note="Superinfection exclusion protein B"
FT                   /id="PRO_0000077738"
FT   TRANSMEM        23..39
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        55..71
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   184 AA;  21557 MW;  84FA6F11668827AE CRC64;
     MMSIEMDPLV ILGRVFSNEP LERTMYMIVI WVGLLLLSPD NWPEYVNERI GIPHVWHVFV
     FALAFSLAIN VHRLSAIASA RYKRFKLRKR IKMQNDKVRS VIQNLTEEQS MVLCAALNEG
     RKYVVTSKQF PYISELIELG VLNKTFSRWN GKHILFPIED IYWTELVASY DPYNIEIKPR
     PISK