SIED1_ARATH
ID SIED1_ARATH Reviewed; 93 AA.
AC Q9FMS4; Q8LB42;
DT 11-DEC-2019, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 03-AUG-2022, entry version 117.
DE RecName: Full=Protein salt-induced and EIN3/EIL1-dependent 1 {ECO:0000303|PubMed:25330213};
GN Name=SIED1 {ECO:0000303|PubMed:25330213};
GN OrderedLocusNames=At5g22270 {ECO:0000312|Araport:AT5G22270};
GN ORFNames=T6G21.5 {ECO:0000312|EMBL:AED93003.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=9501997; DOI=10.1093/dnares/4.6.401;
RA Nakamura Y., Sato S., Kaneko T., Kotani H., Asamizu E., Miyajima N.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. III. Sequence
RT features of the regions of 1,191,918 bp covered by seventeen physically
RT assigned P1 clones.";
RL DNA Res. 4:401-414(1997).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia; TISSUE=Rosette leaf;
RX PubMed=19423640; DOI=10.1093/dnares/dsp009;
RA Iida K., Fukami-Kobayashi K., Toyoda A., Sakaki Y., Kobayashi M., Seki M.,
RA Shinozaki K.;
RT "Analysis of multiple occurrences of alternative splicing events in
RT Arabidopsis thaliana using novel sequenced full-length cDNAs.";
RL DNA Res. 16:155-164(2009).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP FUNCTION, DISRUPTION PHENOTYPE, AND ACTIVITY REGULATION.
RC STRAIN=cv. Columbia;
RX PubMed=25330213; DOI=10.1371/journal.pgen.1004664;
RA Peng J., Li Z., Wen X., Li W., Shi H., Yang L., Zhu H., Guo H.;
RT "Salt-induced stabilization of EIN3/EIL1 confers salinity tolerance by
RT deterring ROS accumulation in Arabidopsis.";
RL PLoS Genet. 10:E1004664-E1004664(2014).
CC -!- FUNCTION: Involved in ethylene-dependent salt stress responses by
CC reducing reactive oxygen species (ROS) accumulation.
CC {ECO:0000269|PubMed:25330213}.
CC -!- ACTIVITY REGULATION: Triggered by EIN3. {ECO:0000269|PubMed:25330213}.
CC -!- INTERACTION:
CC Q9FMS4; Q5ICL9: NPR4; NbExp=3; IntAct=EBI-25529548, EBI-1392093;
CC -!- DISRUPTION PHENOTYPE: Increased sensitivity to salt.
CC {ECO:0000269|PubMed:25330213}.
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DR EMBL; AB007651; BAB08325.1; -; Genomic_DNA.
DR EMBL; CP002688; AED93003.1; -; Genomic_DNA.
DR EMBL; AY052339; AAK96531.1; -; mRNA.
DR EMBL; AY098961; AAM19971.1; -; mRNA.
DR EMBL; AK319023; BAH57138.1; -; mRNA.
DR EMBL; AY087434; AAM64981.1; -; mRNA.
DR RefSeq; NP_197619.1; NM_122132.3.
DR AlphaFoldDB; Q9FMS4; -.
DR IntAct; Q9FMS4; 1.
DR STRING; 3702.AT5G22270.1; -.
DR PaxDb; Q9FMS4; -.
DR PRIDE; Q9FMS4; -.
DR ProteomicsDB; 181147; -.
DR EnsemblPlants; AT5G22270.1; AT5G22270.1; AT5G22270.
DR GeneID; 832287; -.
DR Gramene; AT5G22270.1; AT5G22270.1; AT5G22270.
DR KEGG; ath:AT5G22270; -.
DR Araport; AT5G22270; -.
DR TAIR; locus:2176327; AT5G22270.
DR HOGENOM; CLU_2489865_0_0_1; -.
DR InParanoid; Q9FMS4; -.
DR OMA; CNSHVLL; -.
DR OrthoDB; 1622815at2759; -.
DR PhylomeDB; Q9FMS4; -.
DR PRO; PR:Q9FMS4; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9FMS4; baseline and differential.
DR GO; GO:0009873; P:ethylene-activated signaling pathway; IMP:UniProtKB.
DR GO; GO:2000377; P:regulation of reactive oxygen species metabolic process; IMP:UniProtKB.
DR GO; GO:0009651; P:response to salt stress; IMP:UniProtKB.
PE 1: Evidence at protein level;
KW Ethylene signaling pathway; Reference proteome; Stress response.
FT CHAIN 1..93
FT /note="Protein salt-induced and EIN3/EIL1-dependent 1"
FT /id="PRO_0000448700"
FT REGION 23..46
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 23..37
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 31
FT /note="S -> L (in Ref. 5; AAM64981)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 93 AA; 9792 MW; 34A370EB6A212757 CRC64;
MNQEAASNLG LDLKLNISPS LDSSLLTESS SSSLCSEEAE GGGGEAKSMV VVGCPNCIMY
IITSLENDPR CPRCNSHVLL DFLTGNHSKK STS
