BH087_ARATH
ID BH087_ARATH Reviewed; 373 AA.
AC Q8S3D2; Q84W35; Q9LIG3;
DT 16-DEC-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2002, sequence version 1.
DT 03-AUG-2022, entry version 123.
DE RecName: Full=Transcription factor bHLH87;
DE AltName: Full=Basic helix-loop-helix protein 87;
DE Short=AtbHLH87;
DE Short=bHLH 87;
DE AltName: Full=Transcription factor EN 121;
DE AltName: Full=bHLH transcription factor bHLH087;
GN Name=BHLH87; Synonyms=EN121; OrderedLocusNames=At3g21330; ORFNames=MHC9.1;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], TISSUE SPECIFICITY, GENE FAMILY, AND
RP NOMENCLATURE.
RC STRAIN=cv. Columbia; TISSUE=Flower;
RX PubMed=12679534; DOI=10.1093/molbev/msg088;
RA Heim M.A., Jakoby M., Werber M., Martin C., Weisshaar B., Bailey P.C.;
RT "The basic helix-loop-helix transcription factor family in plants: a
RT genome-wide study of protein structure and functional diversity.";
RL Mol. Biol. Evol. 20:735-747(2003).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10907853; DOI=10.1093/dnares/7.3.217;
RA Kaneko T., Katoh T., Sato S., Nakamura Y., Asamizu E., Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 3. II. Sequence
RT features of the 4,251,695 bp regions covered by 90 P1, TAC and BAC
RT clones.";
RL DNA Res. 7:217-221(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Kim C.J., Chen H., Cheuk R., Shinn P., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (DEC-2004) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP GENE FAMILY.
RX PubMed=12897250; DOI=10.1105/tpc.013839;
RA Toledo-Ortiz G., Huq E., Quail P.H.;
RT "The Arabidopsis basic/helix-loop-helix transcription factor family.";
RL Plant Cell 15:1749-1770(2003).
RN [7]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=14600211; DOI=10.1105/tpc.151140;
RA Bailey P.C., Martin C., Toledo-Ortiz G., Quail P.H., Huq E., Heim M.A.,
RA Jakoby M., Werber M., Weisshaar B.;
RT "Update on the basic helix-loop-helix transcription factor gene family in
RT Arabidopsis thaliana.";
RL Plant Cell 15:2497-2502(2003).
CC -!- SUBUNIT: Homodimer. {ECO:0000305}.
CC -!- INTERACTION:
CC Q8S3D2; Q9FG01: ATO; NbExp=3; IntAct=EBI-15194565, EBI-4475455;
CC Q8S3D2; Q9FY69: BHLH143; NbExp=3; IntAct=EBI-15194565, EBI-15194247;
CC Q8S3D2; Q9C5X0: IAA34; NbExp=3; IntAct=EBI-15194565, EBI-3946459;
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981}.
CC -!- TISSUE SPECIFICITY: Flowers. {ECO:0000269|PubMed:12679534}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAB03046.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AF488617; AAM10960.1; -; mRNA.
DR EMBL; AP001305; BAB03046.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002686; AEE76493.1; -; Genomic_DNA.
DR EMBL; BT004279; AAO42279.1; -; mRNA.
DR EMBL; BT020364; AAV85719.1; -; mRNA.
DR RefSeq; NP_188770.1; NM_113028.3.
DR AlphaFoldDB; Q8S3D2; -.
DR SMR; Q8S3D2; -.
DR BioGRID; 7019; 21.
DR IntAct; Q8S3D2; 19.
DR STRING; 3702.AT3G21330.1; -.
DR PaxDb; Q8S3D2; -.
DR PRIDE; Q8S3D2; -.
DR EnsemblPlants; AT3G21330.1; AT3G21330.1; AT3G21330.
DR GeneID; 821687; -.
DR Gramene; AT3G21330.1; AT3G21330.1; AT3G21330.
DR KEGG; ath:AT3G21330; -.
DR Araport; AT3G21330; -.
DR TAIR; locus:2089418; AT3G21330.
DR eggNOG; ENOG502QR69; Eukaryota.
DR HOGENOM; CLU_045758_0_0_1; -.
DR InParanoid; Q8S3D2; -.
DR OMA; MVERPKR; -.
DR OrthoDB; 1219027at2759; -.
DR PhylomeDB; Q8S3D2; -.
DR PRO; PR:Q8S3D2; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q8S3D2; baseline and differential.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IPI:TAIR.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:TAIR.
DR Gene3D; 4.10.280.10; -; 1.
DR InterPro; IPR011598; bHLH_dom.
DR InterPro; IPR036638; HLH_DNA-bd_sf.
DR InterPro; IPR045843; IND-like.
DR PANTHER; PTHR45914; PTHR45914; 2.
DR Pfam; PF00010; HLH; 1.
DR SMART; SM00353; HLH; 1.
DR SUPFAM; SSF47459; SSF47459; 1.
DR PROSITE; PS50888; BHLH; 1.
PE 1: Evidence at protein level;
KW DNA-binding; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..373
FT /note="Transcription factor bHLH87"
FT /id="PRO_0000358779"
FT DOMAIN 275..324
FT /note="bHLH"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00981"
FT REGION 127..227
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 127..146
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 155..169
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 187..217
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 321
FT /note="L -> F (in Ref. 4; AAO42279)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 373 AA; 41321 MW; BB14A0896794BA97 CRC64;
MEGLESVYAQ AMYGMTRESK IMEHQGSDLI WGGNELMARE LCSSSSYHHQ LINPNLSSCF
MSDLGVLGEI QQQQHVGNRA SSIDPSSLDC LLSATSNSNN TSTEDDEGIS VLFSDCQTLW
SFGGVSSAES ENREITTETT TTIKPKPLKR NRGGDGGTTE TTTTTTKPKS LKRNRGDETG
SHFSLVHPQD DSEKGGFKLI YDENQSKSKK PRTEKERGGS SNISFQHSTC LSDNVEPDAE
AIAQMKEMIY RAAAFRPVNF GLEIVEKPKR KNVKISTDPQ TVAARQRRER ISEKIRVLQT
LVPGGTKMDT ASMLDEAANY LKFLRAQVKA LENLRPKLDQ TNLSFSSAPT SFPLFHPSFL
PLQNPNQIHH PEC
