ID   SIG1S_REOVJ             Reviewed;         125 AA.
AC   P32868; Q6LDZ2;
DT   01-OCT-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1993, sequence version 1.
DT   25-MAY-2022, entry version 55.
DE   RecName: Full=Protein sigma-1-small;
DE            Short=Sigma1s;
DE   AltName: Full=Sigma-s;
DE   AltName: Full=Sigma1NS;
DE   AltName: Full=Sigma1bNS;
DE   AltName: Full=p14;
GN   Name=S1;
OS   Reovirus type 2 (strain D5/Jones) (T2J) (Mammalian orthoreovirus 2).
OC   Viruses; Riboviria; Orthornavirae; Duplornaviricota; Resentoviricetes;
OC   Reovirales; Reoviridae; Spinareovirinae; Orthoreovirus.
OX   NCBI_TaxID=10885;
OH   NCBI_TaxID=40674; Mammalia.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=3855545; DOI=10.1073/pnas.82.1.24;
RA   Cashdollar L.W., Chmelo R.A., Wiener J.R., Joklik W.K.;
RT   "Sequences of the S1 genes of the three serotypes of reovirus.";
RL   Proc. Natl. Acad. Sci. U.S.A. 82:24-28(1985).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=2335823; DOI=10.1128/jvi.64.6.2976-2989.1990;
RA   Nibert M.L., Dermody T.S., Fields B.N.;
RT   "Structure of the reovirus cell-attachment protein: a model for the domain
RT   organization of sigma 1.";
RL   J. Virol. 64:2976-2989(1990).
CC   -!- SIMILARITY: Belongs to the orthoreovirus sigma-1s protein family.
CC       {ECO:0000305}.
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DR   EMBL; M10261; AAA66880.1; -; Genomic_RNA.
DR   EMBL; M35964; AAA47252.1; -; Genomic_RNA.
DR   PIR; D34829; D34829.
DR   SMR; P32868; -.
DR   Proteomes; UP000006370; Genome.
DR   GO; GO:0039592; P:suppression by virus of G2/M transition of host mitotic cell cycle; IEA:UniProtKB-KW.
DR   InterPro; IPR003478; Capsid_sigma_1s.
DR   Pfam; PF02454; Sigma_1s; 1.
PE   3: Inferred from homology;
KW   Host G2/M cell cycle arrest by virus; Host-virus interaction;
KW   Modulation of host cell cycle by virus.
FT   CHAIN           1..125
FT                   /note="Protein sigma-1-small"
FT                   /id="PRO_0000222756"
SQ   SEQUENCE   125 AA;  14560 MW;  71AFD9523EB8A789 CRC64;
     MENQPTRNTR SRKLRNKLKT SLLMSTGSVT SLIQSKDNWV DYLYACQPLN RELVRTAIEL
     IDSSEMSPAY RLALAESIRV YPSWVTESML QNSELASWIQ SRIISLSEHQ DWKLKYQPLL
     MTLDH