BH089_ARATH
ID BH089_ARATH Reviewed; 420 AA.
AC Q9LND0;
DT 16-DEC-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 03-AUG-2022, entry version 129.
DE RecName: Full=Transcription factor bHLH89;
DE AltName: Full=Basic helix-loop-helix protein 89;
DE Short=AtbHLH89;
DE Short=bHLH 89;
DE AltName: Full=Transcription factor EN 24;
DE AltName: Full=bHLH transcription factor bHLH089;
GN Name=BHLH89; Synonyms=EN24; OrderedLocusNames=At1g06170; ORFNames=F9P14.3;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], TISSUE SPECIFICITY, GENE FAMILY, AND
RP NOMENCLATURE.
RC STRAIN=cv. Columbia; TISSUE=Flower;
RX PubMed=12679534; DOI=10.1093/molbev/msg088;
RA Heim M.A., Jakoby M., Werber M., Martin C., Weisshaar B., Bailey P.C.;
RT "The basic helix-loop-helix transcription factor family in plants: a
RT genome-wide study of protein structure and functional diversity.";
RL Mol. Biol. Evol. 20:735-747(2003).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [5]
RP GENE FAMILY.
RX PubMed=12897250; DOI=10.1105/tpc.013839;
RA Toledo-Ortiz G., Huq E., Quail P.H.;
RT "The Arabidopsis basic/helix-loop-helix transcription factor family.";
RL Plant Cell 15:1749-1770(2003).
RN [6]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=14600211; DOI=10.1105/tpc.151140;
RA Bailey P.C., Martin C., Toledo-Ortiz G., Quail P.H., Huq E., Heim M.A.,
RA Jakoby M., Werber M., Weisshaar B.;
RT "Update on the basic helix-loop-helix transcription factor gene family in
RT Arabidopsis thaliana.";
RL Plant Cell 15:2497-2502(2003).
CC -!- SUBUNIT: Homodimer. {ECO:0000305}.
CC -!- INTERACTION:
CC Q9LND0; O49608: MYB32; NbExp=3; IntAct=EBI-25523114, EBI-15200192;
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981}.
CC -!- TISSUE SPECIFICITY: Flowers. {ECO:0000269|PubMed:12679534}.
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DR EMBL; AF488619; AAM10962.1; -; mRNA.
DR EMBL; AC025290; AAF80214.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE27953.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE27954.1; -; Genomic_DNA.
DR EMBL; BT004262; AAO42264.1; -; mRNA.
DR PIR; C86197; C86197.
DR RefSeq; NP_172107.1; NM_100498.4.
DR RefSeq; NP_973769.1; NM_202040.1.
DR AlphaFoldDB; Q9LND0; -.
DR SMR; Q9LND0; -.
DR BioGRID; 22368; 6.
DR IntAct; Q9LND0; 1.
DR STRING; 3702.AT1G06170.2; -.
DR PaxDb; Q9LND0; -.
DR PRIDE; Q9LND0; -.
DR EnsemblPlants; AT1G06170.1; AT1G06170.1; AT1G06170.
DR EnsemblPlants; AT1G06170.2; AT1G06170.2; AT1G06170.
DR GeneID; 837126; -.
DR Gramene; AT1G06170.1; AT1G06170.1; AT1G06170.
DR Gramene; AT1G06170.2; AT1G06170.2; AT1G06170.
DR KEGG; ath:AT1G06170; -.
DR Araport; AT1G06170; -.
DR TAIR; locus:2038510; AT1G06170.
DR eggNOG; ENOG502QQIQ; Eukaryota.
DR HOGENOM; CLU_045325_0_0_1; -.
DR InParanoid; Q9LND0; -.
DR OMA; MYDEENN; -.
DR OrthoDB; 948814at2759; -.
DR PhylomeDB; Q9LND0; -.
DR PRO; PR:Q9LND0; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9LND0; baseline and differential.
DR Genevisible; Q9LND0; AT.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0070888; F:E-box binding; IPI:TAIR.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0048658; P:anther wall tapetum development; IGI:TAIR.
DR GO; GO:0052543; P:callose deposition in cell wall; IGI:TAIR.
DR GO; GO:0009555; P:pollen development; IGI:TAIR.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IEP:TAIR.
DR CDD; cd18918; bHLH_AtMYC1_like; 1.
DR Gene3D; 4.10.280.10; -; 1.
DR InterPro; IPR045895; bHLH91-like.
DR InterPro; IPR011598; bHLH_dom.
DR InterPro; IPR036638; HLH_DNA-bd_sf.
DR InterPro; IPR045896; MYC1-like_bHLH.
DR PANTHER; PTHR46834; PTHR46834; 1.
DR Pfam; PF00010; HLH; 1.
DR SMART; SM00353; HLH; 1.
DR SUPFAM; SSF47459; SSF47459; 1.
DR PROSITE; PS50888; BHLH; 1.
PE 1: Evidence at protein level;
KW DNA-binding; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..420
FT /note="Transcription factor bHLH89"
FT /id="PRO_0000358780"
FT DOMAIN 212..261
FT /note="bHLH"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00981"
FT REGION 196..216
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 420 AA; 47033 MW; C6F27EA79CBFC76F CRC64;
MGGGGMFEEI GCFDPNAPAE MTAESSFSPS EPPPTITVIG SNSNSNCSLE DLSAFHLSPQ
DSSLPASASA YAHQLHINAT PNCDHQFQSS MHQTLQDPSY AQQSNHWDNG YQDFVNLGPN
HTTPDLLSLL QLPRSSLPPF ANPSIQDIIM TTSSSVAAYD PLFHLNFPLQ PPNGSFMGVD
QDQTETNQGV NLMYDEENNN LDDGLNRKGR GSKKRKIFPT ERERRVHFKD RFGDLKNLIP
NPTKNDRASI VGEAIDYIKE LLRTIDEFKL LVEKKRVKQR NREGDDVVDE NFKAQSEVVE
QCLINKKNNA LRCSWLKRKS KFTDVDVRII DDEVTIKIVQ KKKINCLLFV SKVVDQLELD
LHHVAGAQIG EHHSFLFNAK ISEGSSVYAS AIADRVMEVL KKQYMEALSA NNGYHCYSSD
