BH090_ARATH
ID BH090_ARATH Reviewed; 441 AA.
AC Q0WNR2; Q9SGY8; Q9SGY9; Q9XII8;
DT 16-DEC-2008, integrated into UniProtKB/Swiss-Prot.
DT 05-SEP-2006, sequence version 1.
DT 03-AUG-2022, entry version 104.
DE RecName: Full=Transcription factor bHLH90;
DE AltName: Full=Basic helix-loop-helix protein 90;
DE Short=AtbHLH90;
DE Short=bHLH 90;
DE AltName: Full=Transcription factor EN 50;
DE AltName: Full=bHLH transcription factor bHLH090;
GN Name=BHLH90; Synonyms=EN50; OrderedLocusNames=At1g10610;
GN ORFNames=F20B24.4, F20B24.5, T10O24.26;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [MRNA] OF 265-441, TISSUE SPECIFICITY, GENE FAMILY, AND
RP NOMENCLATURE.
RC STRAIN=cv. Columbia;
RX PubMed=12679534; DOI=10.1093/molbev/msg088;
RA Heim M.A., Jakoby M., Werber M., Martin C., Weisshaar B., Bailey P.C.;
RT "The basic helix-loop-helix transcription factor family in plants: a
RT genome-wide study of protein structure and functional diversity.";
RL Mol. Biol. Evol. 20:735-747(2003).
RN [5]
RP GENE FAMILY.
RX PubMed=12897250; DOI=10.1105/tpc.013839;
RA Toledo-Ortiz G., Huq E., Quail P.H.;
RT "The Arabidopsis basic/helix-loop-helix transcription factor family.";
RL Plant Cell 15:1749-1770(2003).
RN [6]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=14600211; DOI=10.1105/tpc.151140;
RA Bailey P.C., Martin C., Toledo-Ortiz G., Quail P.H., Huq E., Heim M.A.,
RA Jakoby M., Werber M., Weisshaar B.;
RT "Update on the basic helix-loop-helix transcription factor gene family in
RT Arabidopsis thaliana.";
RL Plant Cell 15:2497-2502(2003).
CC -!- SUBUNIT: Homodimer. {ECO:0000305}.
CC -!- INTERACTION:
CC Q0WNR2; Q84TK1: BHLH10; NbExp=3; IntAct=EBI-15216058, EBI-15200952;
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981}.
CC -!- TISSUE SPECIFICITY: Expressed constitutively in roots, leaves, stems,
CC and flowers. {ECO:0000269|PubMed:12679534}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAD39586.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=AAF17654.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=AAF17655.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AC007067; AAD39586.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AC009398; AAF17654.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AC009398; AAF17655.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002684; AEE28609.1; -; Genomic_DNA.
DR EMBL; AK229375; BAF01237.1; -; mRNA.
DR EMBL; AF488620; -; NOT_ANNOTATED_CDS; mRNA.
DR PIR; F86239; F86239.
DR RefSeq; NP_172531.2; NM_100937.3.
DR AlphaFoldDB; Q0WNR2; -.
DR SMR; Q0WNR2; -.
DR BioGRID; 22844; 6.
DR IntAct; Q0WNR2; 6.
DR STRING; 3702.AT1G10610.1; -.
DR PaxDb; Q0WNR2; -.
DR PRIDE; Q0WNR2; -.
DR EnsemblPlants; AT1G10610.1; AT1G10610.1; AT1G10610.
DR GeneID; 837604; -.
DR Gramene; AT1G10610.1; AT1G10610.1; AT1G10610.
DR KEGG; ath:AT1G10610; -.
DR Araport; AT1G10610; -.
DR TAIR; locus:2020003; AT1G10610.
DR eggNOG; ENOG502QTEQ; Eukaryota.
DR HOGENOM; CLU_037477_0_0_1; -.
DR InParanoid; Q0WNR2; -.
DR OMA; YSGIHGE; -.
DR OrthoDB; 922298at2759; -.
DR PhylomeDB; Q0WNR2; -.
DR PRO; PR:Q0WNR2; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q0WNR2; baseline and differential.
DR Genevisible; Q0WNR2; AT.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:GO_Central.
DR Gene3D; 4.10.280.10; -; 1.
DR InterPro; IPR011598; bHLH_dom.
DR InterPro; IPR036638; HLH_DNA-bd_sf.
DR InterPro; IPR025610; MYC/MYB_N.
DR Pfam; PF14215; bHLH-MYC_N; 1.
DR Pfam; PF00010; HLH; 1.
DR SMART; SM00353; HLH; 1.
DR SUPFAM; SSF47459; SSF47459; 1.
DR PROSITE; PS50888; BHLH; 1.
PE 1: Evidence at protein level;
KW DNA-binding; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..441
FT /note="Transcription factor bHLH90"
FT /id="PRO_0000358781"
FT DOMAIN 260..309
FT /note="bHLH"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00981"
FT CONFLICT 289
FT /note="K -> R (in Ref. 4; AF488620)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 441 AA; 50234 MW; F7F673466B7A3BE9 CRC64;
MMMMRGGERV KEFLRPFVDS RTWDLCVIWK LGDDPSRFIE WVGCCCSGCY IDKNIKLENS
EEGGTGRKKK ASFCRDDHNK HRIRTLACEA LSRFPLFMPL YPGIHGEVVM SKSPKWLVNS
GSKMEMFSTR VLVPVSDGLV ELFAFDMRPF DESMVHLIMS RCTTFFEPFP EQRLQFRIIP
RAEESMSSGV NLSVEGGGSS SVSNPSSETQ NLFGNYPNAS CVEILREEQT PCLIMNKEKD
VVVQNANDSK ANKKLLPTEN FKSKNLHSER KRRERINQAM YGLRAVVPKI TKLNKIGIFS
DAVDYINELL VEKQKLEDEL KGINEMECKE IAAEEQSAIA DPEAERVSSK SNKRVKKNEV
KIEVHETGER DFLIRVVQEH KQDGFKRLIE AVDLCELEII DVNFTRLDLT VMTVLNVKAN
KDGIACGILR DLLLKMMITS I
