ID   SIGE_SALPA              Reviewed;         113 AA.
AC   Q5PGB1;
DT   01-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   04-JAN-2005, sequence version 1.
DT   25-MAY-2022, entry version 76.
DE   RecName: Full=Chaperone protein SigE;
GN   Name=sigE; Synonyms=pipC; OrderedLocusNames=SPA1760;
OS   Salmonella paratyphi A (strain ATCC 9150 / SARB42).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=295319;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 9150 / SARB42;
RX   PubMed=15531882; DOI=10.1038/ng1470;
RA   McClelland M., Sanderson K.E., Clifton S.W., Latreille P., Porwollik S.,
RA   Sabo A., Meyer R., Bieri T., Ozersky P., McLellan M., Harkins C.R.,
RA   Wang C., Nguyen C., Berghoff A., Elliott G., Kohlberg S., Strong C., Du F.,
RA   Carter J., Kremizki C., Layman D., Leonard S., Sun H., Fulton L., Nash W.,
RA   Miner T., Minx P., Delehaunty K., Fronick C., Magrini V., Nhan M.,
RA   Warren W., Florea L., Spieth J., Wilson R.K.;
RT   "Comparison of genome degradation in Paratyphi A and Typhi, human-
RT   restricted serovars of Salmonella enterica that cause typhoid.";
RL   Nat. Genet. 36:1268-1274(2004).
CC   -!- FUNCTION: Molecular chaperone required for SopB/SigD stabilization and
CC       secretion. {ECO:0000250}.
CC   -!- SUBUNIT: Homodimer or higher-order oligomers. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
CC   -!- INDUCTION: Transcriptionally regulated by InvF and SicA. Also regulated
CC       by SirA (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the IpgE/SigE chaperone family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP000026; AAV77678.1; -; Genomic_DNA.
DR   RefSeq; WP_000444724.1; NC_006511.1.
DR   AlphaFoldDB; Q5PGB1; -.
DR   SMR; Q5PGB1; -.
DR   EnsemblBacteria; AAV77678; AAV77678; SPA1760.
DR   KEGG; spt:SPA1760; -.
DR   HOGENOM; CLU_2131737_0_0_6; -.
DR   OMA; DDEIQVY; -.
DR   Proteomes; UP000008185; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   CDD; cd17022; T3SC_IA_SigE-like; 1.
DR   InterPro; IPR013095; T3SS_chaperone.
DR   Pfam; PF07824; Chaperone_III; 1.
DR   PIRSF; PIRSF034754; T3SS_chaperone; 1.
PE   3: Inferred from homology;
KW   Chaperone; Cytoplasm; Virulence.
FT   CHAIN           1..113
FT                   /note="Chaperone protein SigE"
FT                   /id="PRO_0000160573"
SQ   SEQUENCE   113 AA;  12751 MW;  34DEE3AB3944560E CRC64;
     MESLLNRLYD ALGLDAPEDE PLLIIDDGIQ VYFNESDHTL EMCCPFMPLP DDILTLQHFL
     RLNYTSAVTI GADADNTALV ALYRLPQTST EEEALTGFEL FISNVKQLKE HYA