ID   SIGE_SALTI              Reviewed;         113 AA.
AC   Q8Z7R2; Q7C972;
DT   01-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   25-MAY-2022, entry version 98.
DE   RecName: Full=Chaperone protein SigE;
GN   Name=sigE; Synonyms=pipC; OrderedLocusNames=STY1120, t1829;
OS   Salmonella typhi.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=90370;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CT18;
RX   PubMed=11677608; DOI=10.1038/35101607;
RA   Parkhill J., Dougan G., James K.D., Thomson N.R., Pickard D., Wain J.,
RA   Churcher C.M., Mungall K.L., Bentley S.D., Holden M.T.G., Sebaihia M.,
RA   Baker S., Basham D., Brooks K., Chillingworth T., Connerton P., Cronin A.,
RA   Davis P., Davies R.M., Dowd L., White N., Farrar J., Feltwell T.,
RA   Hamlin N., Haque A., Hien T.T., Holroyd S., Jagels K., Krogh A.,
RA   Larsen T.S., Leather S., Moule S., O'Gaora P., Parry C., Quail M.A.,
RA   Rutherford K.M., Simmonds M., Skelton J., Stevens K., Whitehead S.,
RA   Barrell B.G.;
RT   "Complete genome sequence of a multiple drug resistant Salmonella enterica
RT   serovar Typhi CT18.";
RL   Nature 413:848-852(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700931 / Ty2;
RX   PubMed=12644504; DOI=10.1128/jb.185.7.2330-2337.2003;
RA   Deng W., Liou S.-R., Plunkett G. III, Mayhew G.F., Rose D.J., Burland V.,
RA   Kodoyianni V., Schwartz D.C., Blattner F.R.;
RT   "Comparative genomics of Salmonella enterica serovar Typhi strains Ty2 and
RT   CT18.";
RL   J. Bacteriol. 185:2330-2337(2003).
CC   -!- FUNCTION: Molecular chaperone required for SopB/SigD stabilization and
CC       secretion. {ECO:0000250}.
CC   -!- SUBUNIT: Homodimer or higher-order oligomers. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
CC   -!- INDUCTION: Transcriptionally regulated by InvF and SicA. Also regulated
CC       by SirA (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the IpgE/SigE chaperone family. {ECO:0000305}.
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DR   EMBL; AL513382; CAD08216.1; -; Genomic_DNA.
DR   EMBL; AE014613; AAO69450.1; -; Genomic_DNA.
DR   RefSeq; NP_455587.1; NC_003198.1.
DR   RefSeq; WP_000444726.1; NZ_WSUR01000018.1.
DR   AlphaFoldDB; Q8Z7R2; -.
DR   SMR; Q8Z7R2; -.
DR   STRING; 220341.16502264; -.
DR   EnsemblBacteria; AAO69450; AAO69450; t1829.
DR   KEGG; stt:t1829; -.
DR   KEGG; sty:STY1120; -.
DR   PATRIC; fig|220341.7.peg.1123; -.
DR   eggNOG; ENOG5033835; Bacteria.
DR   HOGENOM; CLU_2131737_0_0_6; -.
DR   OMA; DDEIQVY; -.
DR   Proteomes; UP000000541; Chromosome.
DR   Proteomes; UP000002670; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   CDD; cd17022; T3SC_IA_SigE-like; 1.
DR   InterPro; IPR013095; T3SS_chaperone.
DR   Pfam; PF07824; Chaperone_III; 1.
DR   PIRSF; PIRSF034754; T3SS_chaperone; 1.
PE   3: Inferred from homology;
KW   Chaperone; Cytoplasm; Virulence.
FT   CHAIN           1..113
FT                   /note="Chaperone protein SigE"
FT                   /id="PRO_0000160574"
SQ   SEQUENCE   113 AA;  12709 MW;  3F9EE3B194595613 CRC64;
     MESLLNRLYD ALGLDAPEDE PLLIIDDGIQ VYFNESDHTL EMCCPFMPLP DDTLTLQHFL
     RLNYASAVTI GADADNTALV ALYRLPQTST EEEALTGFEL FISNVKQLKE HYA