ID   SIGK_MYCSS              Reviewed;         193 AA.
AC   Q1B3Q8;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   11-JUL-2006, sequence version 1.
DT   03-AUG-2022, entry version 87.
DE   RecName: Full=RNA polymerase sigma factor SigK;
DE   AltName: Full=Sigma-K factor;
GN   Name=sigK; OrderedLocusNames=Mmcs_4371;
OS   Mycobacterium sp. (strain MCS).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; unclassified Mycobacterium.
OX   NCBI_TaxID=164756;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MCS;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA   Martinez M., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N.,
RA   Kim E., Miller C.D., Hughes J.E., Anderson A.J., Sims R.C., Richardson P.;
RT   "Complete sequence of chromosome of Mycobacterium sp. MCS.";
RL   Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Sigma factors are initiation factors that promote the
CC       attachment of RNA polymerase to specific initiation sites and are then
CC       released. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the sigma-70 factor family. ECF subfamily.
CC       {ECO:0000305}.
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DR   EMBL; CP000384; ABG10476.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q1B3Q8; -.
DR   SMR; Q1B3Q8; -.
DR   KEGG; mmc:Mmcs_4371; -.
DR   HOGENOM; CLU_047691_9_3_11; -.
DR   OMA; KGRFFTW; -.
DR   BioCyc; MSP164756:G1G6O-4467-MON; -.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0016987; F:sigma factor activity; IEA:UniProtKB-KW.
DR   GO; GO:0006352; P:DNA-templated transcription, initiation; IEA:InterPro.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR039425; RNA_pol_sigma-70-like.
DR   InterPro; IPR014284; RNA_pol_sigma-70_dom.
DR   InterPro; IPR007627; RNA_pol_sigma70_r2.
DR   InterPro; IPR007630; RNA_pol_sigma70_r4.
DR   InterPro; IPR013325; RNA_pol_sigma_r2.
DR   InterPro; IPR013324; RNA_pol_sigma_r3/r4-like.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   PANTHER; PTHR43133; PTHR43133; 1.
DR   Pfam; PF04542; Sigma70_r2; 1.
DR   Pfam; PF04545; Sigma70_r4; 1.
DR   SUPFAM; SSF88659; SSF88659; 1.
DR   SUPFAM; SSF88946; SSF88946; 1.
DR   TIGRFAMs; TIGR02937; sigma70-ECF; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Sigma factor; Transcription; Transcription regulation.
FT   CHAIN           1..193
FT                   /note="RNA polymerase sigma factor SigK"
FT                   /id="PRO_0000313843"
FT   DNA_BIND        161..180
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000250"
FT   MOTIF           59..72
FT                   /note="Polymerase core binding"
SQ   SEQUENCE   193 AA;  21658 MW;  44A5983BB07E6F96 CRC64;
     MTALTQPVRL PFVTTDLDVL LRQVAERDVD AFAALYDRTR SRVYGMVTRV LRDPGYSEET
     TQDIYLQVWR SAGSYDPKAG SPMAWLLTLA HRRAVDRVRS EEAASQRESR YGAASVDPPV
     DHVADSVILL DERRRVVDCM GSLSDLQREA IQLAYYEGLT YVQVSERLSA NLATIKSRMR
     GGIRGLKNCL GMS