ID   SIKE1_XENLA             Reviewed;         205 AA.
AC   Q6GP65;
DT   21-AUG-2007, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 45.
DE   RecName: Full=Suppressor of IKBKE 1;
DE   AltName: Full=Suppressor of IKK-epsilon;
GN   Name=sike1; Synonyms=sike;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Spleen;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Suppressor of IKK-epsilon. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SIKE family. {ECO:0000305}.
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DR   EMBL; BC073278; AAH73278.1; -; mRNA.
DR   RefSeq; NP_001085744.1; NM_001092275.1.
DR   AlphaFoldDB; Q6GP65; -.
DR   SMR; Q6GP65; -.
DR   PRIDE; Q6GP65; -.
DR   DNASU; 444171; -.
DR   GeneID; 444171; -.
DR   KEGG; xla:444171; -.
DR   CTD; 444171; -.
DR   Xenbase; XB-GENE-1003391; sike1.L.
DR   OrthoDB; 1368908at2759; -.
DR   Proteomes; UP000186698; Chromosome 2L.
DR   Bgee; 444171; Expressed in muscle tissue and 19 other tissues.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   InterPro; IPR008555; SIKE.
DR   PANTHER; PTHR12186; PTHR12186; 1.
DR   Pfam; PF05769; SIKE; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil; Cytoplasm; Reference proteome.
FT   CHAIN           1..205
FT                   /note="Suppressor of IKBKE 1"
FT                   /id="PRO_0000299055"
FT   COILED          4..32
FT                   /evidence="ECO:0000255"
FT   COILED          154..192
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   205 AA;  23860 MW;  5E03DF21AF9A3526 CRC64;
     MTCTIDKILQ DAKTLLERLK DHDNAAESLI DQSSVLHKRV KAMKEVGTAM PEKYQEELAE
     IKDASKLRPH VLLCQENTQI RDLQLENKEL WLSLEEHQYA LELIMSKYRK QMLQLIANKI
     PAPTEPVLEA HKTFSSDLEC QIDRICVIGD AMRKAIQLDE DQAYNIQERL AQLELENKEL
     REILSVRNES LRSSKKESEW NFSEK