ID   SILB_SALTM              Reviewed;         430 AA.
AC   Q9ZHD0;
DT   27-APR-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1999, sequence version 1.
DT   25-MAY-2022, entry version 59.
DE   RecName: Full=Putative membrane fusion protein SilB;
DE   Flags: Precursor;
GN   Name=silB;
OS   Salmonella typhimurium.
OG   Plasmid pMG101.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=90371;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=9930866; DOI=10.1038/5545;
RA   Gupta A., Matsui K., Lo J.-F., Silver S.;
RT   "Molecular basis for resistance to silver cations in Salmonella.";
RL   Nat. Med. 5:183-188(1999).
CC   -!- FUNCTION: Component of the sil cation efflux system that confers
CC       resistance to silver. May be part of a three-component cation/proton
CC       antiporter.
CC   -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC       family. {ECO:0000305}.
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DR   EMBL; AF067954; AAD11748.1; -; Genomic_DNA.
DR   RefSeq; WP_001446341.1; NZ_JAETZG010000001.1.
DR   AlphaFoldDB; Q9ZHD0; -.
DR   SMR; Q9ZHD0; -.
DR   GO; GO:0016020; C:membrane; IEA:InterPro.
DR   GO; GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
DR   InterPro; IPR032317; HlyD_D23.
DR   InterPro; IPR045800; HMBD.
DR   InterPro; IPR006143; RND_pump_MFP.
DR   Pfam; PF16576; HlyD_D23; 1.
DR   Pfam; PF19335; HMBD; 1.
DR   TIGRFAMs; TIGR01730; RND_mfp; 1.
PE   3: Inferred from homology;
KW   Antiport; Ion transport; Plasmid; Signal; Transport.
FT   SIGNAL          1..28
FT                   /evidence="ECO:0000255"
FT   CHAIN           29..430
FT                   /note="Putative membrane fusion protein SilB"
FT                   /id="PRO_0000018715"
FT   REGION          407..430
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        415..430
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   430 AA;  47720 MW;  A3269C6D5F7F80F5 CRC64;
     MASLKIKYAA IIISSLIAGG LISVTAWQYL NSSQKTVPAE QKAPEKKVLF WYDPMKPDTK
     FDKPGKSPFM DMDLVPKYAD ESGDKSSGGI RIDPTQVQNL GLKTQKVTRG MLNYSQTIPA
     NVSYNEYQFV IVQARSDGFV EKVYPLTIGD HVKKGTPLID ITIPEWVEAQ SEFLLLSGTG
     GTPTQIKGVL ERLRLAGMPE EDIQRLRSTR TIQTRFTIKA PIDGVITAFD LRTGMNISKD
     KVVAQIQGMD PVWISAAVPE SIAYLLKDTS QFEISVPAYP DKTFHVEKWN ILPSVDQTTR
     TLQVRLQVTN KDEFLKPGMN AYLKLNTQSQ EMLLIPSQAV IDTGKEQRVI TVDDEGKFVP
     KQIHVLHESQ QQSGIGSGLN EGDTVVVSGL FLIDSEANIT GALERMRHPE KTENSMPAMS
     EQPVNMHSGH