ID   SILC_SALTM              Reviewed;         461 AA.
AC   Q9ZHD2;
DT   27-APR-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1999, sequence version 1.
DT   25-MAY-2022, entry version 80.
DE   RecName: Full=Probable outer membrane lipoprotein SilC;
DE   Flags: Precursor;
GN   Name=silC;
OS   Salmonella typhimurium.
OG   Plasmid pMG101.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=90371;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=9930866; DOI=10.1038/5545;
RA   Gupta A., Matsui K., Lo J.-F., Silver S.;
RT   "Molecular basis for resistance to silver cations in Salmonella.";
RL   Nat. Med. 5:183-188(1999).
CC   -!- FUNCTION: Component of the sil cation-efflux system that confers
CC       resistance to silver. May be part of a three-component cation/proton
CC       antiporter.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000305}; Lipid-anchor
CC       {ECO:0000255|PROSITE-ProRule:PRU00303}.
CC   -!- SIMILARITY: Belongs to the outer membrane factor (OMF) (TC 1.B.17)
CC       family. {ECO:0000305}.
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DR   EMBL; AF067954; AAD11746.1; -; Genomic_DNA.
DR   RefSeq; WP_001507116.1; NZ_WIDF01000005.1.
DR   AlphaFoldDB; Q9ZHD2; -.
DR   SMR; Q9ZHD2; -.
DR   TCDB; 1.B.17.3.4; the outer membrane factor (omf) family.
DR   GeneID; 67375437; -.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015562; F:efflux transmembrane transporter activity; IEA:InterPro.
DR   InterPro; IPR003423; OMP_efflux.
DR   InterPro; IPR010131; RND_efflux_OM_lipoprot_NodT.
DR   Pfam; PF02321; OEP; 2.
DR   TIGRFAMs; TIGR01845; outer_NodT; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
KW   Cell outer membrane; Lipoprotein; Membrane; Palmitate; Plasmid; Signal;
KW   Transmembrane; Transmembrane beta strand.
FT   SIGNAL          1..17
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   CHAIN           18..461
FT                   /note="Probable outer membrane lipoprotein SilC"
FT                   /id="PRO_0000031000"
FT   LIPID           18
FT                   /note="N-palmitoyl cysteine"
FT                   /evidence="ECO:0000305"
FT   LIPID           18
FT                   /note="S-diacylglycerol cysteine"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   461 AA;  51121 MW;  A3A344B783EA768F CRC64;
     MFKLKLLSIS TIFILAGCVS LAPEYQRPPA PVPQQFSLSK NSLTPAVNSY QDTGWRNFFV
     DPQVSRLIGE ALNNNRDLRM AALKVEEARA QFNVTDADRY PQLNASSGIT YNGGLKGDKP
     TTQEYDAGLE LSYELDFFGK LKNMSEADRQ NYFASEEARR AVHILLVSNV SQSYFSQQLA
     YEQLRIARET LKNYEQSYAF VEQQLVTGST NVLALEQARG QIESTRAEIA KREGDLAQAN
     NALQLVLGTY RAVPSEKGIK GGEIAPVKLP PNLSSQILLQ RPDIMEAEYQ LKAADANIGA
     ARAAFFPSIT LTSGLSSSST ELSSLFTSGS GMWNFIPKIE IPIFNAGRNK ANLKLAEIRQ
     QQSVVNYEQK IQSAFKDVSD TLALRDSLSQ QLESQQRYLD SLQITLQRAR GLYASGAVSY
     IEVLDAERSL FATQQTILDL TYSRQVNEIN LFTALGGGWV E