BH113_ARATH
ID BH113_ARATH Reviewed; 270 AA.
AC Q9LT67; Q8LG13;
DT 16-DEC-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 25-MAY-2022, entry version 121.
DE RecName: Full=Transcription factor bHLH113;
DE AltName: Full=Basic helix-loop-helix protein 113;
DE Short=AtbHLH113;
DE Short=bHLH 113;
DE AltName: Full=Transcription factor EN 61;
DE AltName: Full=bHLH transcription factor bHLH113;
GN Name=BHLH113; Synonyms=EN61; OrderedLocusNames=At3g19500;
GN ORFNames=MLD14.24;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10819329; DOI=10.1093/dnares/7.2.131;
RA Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 3. I. Sequence
RT features of the regions of 4,504,864 bp covered by sixty P1 and TAC
RT clones.";
RL DNA Res. 7:131-135(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [MRNA] OF 120-270, GENE FAMILY, AND NOMENCLATURE.
RC STRAIN=cv. Columbia;
RX PubMed=12679534; DOI=10.1093/molbev/msg088;
RA Heim M.A., Jakoby M., Werber M., Martin C., Weisshaar B., Bailey P.C.;
RT "The basic helix-loop-helix transcription factor family in plants: a
RT genome-wide study of protein structure and functional diversity.";
RL Mol. Biol. Evol. 20:735-747(2003).
RN [5]
RP GENE FAMILY.
RX PubMed=12897250; DOI=10.1105/tpc.013839;
RA Toledo-Ortiz G., Huq E., Quail P.H.;
RT "The Arabidopsis basic/helix-loop-helix transcription factor family.";
RL Plant Cell 15:1749-1770(2003).
RN [6]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=14600211; DOI=10.1105/tpc.151140;
RA Bailey P.C., Martin C., Toledo-Ortiz G., Quail P.H., Huq E., Heim M.A.,
RA Jakoby M., Werber M., Weisshaar B.;
RT "Update on the basic helix-loop-helix transcription factor gene family in
RT Arabidopsis thaliana.";
RL Plant Cell 15:2497-2502(2003).
CC -!- SUBUNIT: Homodimer. {ECO:0000305}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981}.
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DR EMBL; AB025624; BAB02475.1; -; Genomic_DNA.
DR EMBL; CP002686; AEE76248.1; -; Genomic_DNA.
DR EMBL; AY084520; AAM61088.1; -; mRNA.
DR EMBL; AF488631; -; NOT_ANNOTATED_CDS; mRNA.
DR RefSeq; NP_566639.1; NM_112837.3.
DR AlphaFoldDB; Q9LT67; -.
DR SMR; Q9LT67; -.
DR BioGRID; 6817; 2.
DR IntAct; Q9LT67; 2.
DR STRING; 3702.AT3G19500.1; -.
DR PaxDb; Q9LT67; -.
DR ProteomicsDB; 240693; -.
DR EnsemblPlants; AT3G19500.1; AT3G19500.1; AT3G19500.
DR GeneID; 821484; -.
DR Gramene; AT3G19500.1; AT3G19500.1; AT3G19500.
DR KEGG; ath:AT3G19500; -.
DR Araport; AT3G19500; -.
DR TAIR; locus:2090679; AT3G19500.
DR eggNOG; ENOG502RXFS; Eukaryota.
DR HOGENOM; CLU_041735_2_2_1; -.
DR InParanoid; Q9LT67; -.
DR OrthoDB; 1492247at2759; -.
DR PhylomeDB; Q9LT67; -.
DR PRO; PR:Q9LT67; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q9LT67; baseline and differential.
DR Genevisible; Q9LT67; AT.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:TAIR.
DR CDD; cd11393; bHLH_AtbHLH_like; 1.
DR Gene3D; 4.10.280.10; -; 1.
DR InterPro; IPR045239; bHLH95_bHLH.
DR InterPro; IPR011598; bHLH_dom.
DR InterPro; IPR036638; HLH_DNA-bd_sf.
DR SUPFAM; SSF47459; SSF47459; 1.
DR PROSITE; PS50888; BHLH; 1.
PE 2: Evidence at transcript level;
KW DNA-binding; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..270
FT /note="Transcription factor bHLH113"
FT /id="PRO_0000358799"
FT DOMAIN 144..193
FT /note="bHLH"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00981"
FT REGION 109..153
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 133..153
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 146
FT /note="E -> D (in Ref. 3; AAM61088)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 270 AA; 28787 MW; D5DC7301B58C35B2 CRC64;
MGDTAEDQDD RAMMEAEGVT SFSELLMFSD GVLSSSSDHQ PEGNVGDGGE DSLGFVFSGK
TGSRMLCFSG GYQNDDESLF LEPSVPTSGV SDLDPSCIKI DCRNSNDACT VDKSTKSSTK
KRTGTGNGQE SDQNRKPGKK GKRNQEKSSV GIAKVRKERL GERIAALQQL VSPYGKTDAA
SVLHEAMGYI KFLQDQIQVL CSPYLINHSL DGGVVTGDVM AAMKAKDLRS RGLCLVPVSS
TVHVENSNGA DFWSPATMGH TTSPSLPQGF
