ID   SIM12_HORSE             Reviewed;          92 AA.
AC   F6USH3;
DT   14-DEC-2011, integrated into UniProtKB/Swiss-Prot.
DT   27-JUL-2011, sequence version 1.
DT   03-AUG-2022, entry version 45.
DE   RecName: Full=Small integral membrane protein 12;
GN   Name=SMIM12;
OS   Equus caballus (Horse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
OX   NCBI_TaxID=9796;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Thoroughbred;
RX   PubMed=19892987; DOI=10.1126/science.1178158;
RA   Wade C.M., Giulotto E., Sigurdsson S., Zoli M., Gnerre S., Imsland F.,
RA   Lear T.L., Adelson D.L., Bailey E., Bellone R.R., Bloecker H., Distl O.,
RA   Edgar R.C., Garber M., Leeb T., Mauceli E., MacLeod J.N., Penedo M.C.T.,
RA   Raison J.M., Sharpe T., Vogel J., Andersson L., Antczak D.F., Biagi T.,
RA   Binns M.M., Chowdhary B.P., Coleman S.J., Della Valle G., Fryc S.,
RA   Guerin G., Hasegawa T., Hill E.W., Jurka J., Kiialainen A., Lindgren G.,
RA   Liu J., Magnani E., Mickelson J.R., Murray J., Nergadze S.G., Onofrio R.,
RA   Pedroni S., Piras M.F., Raudsepp T., Rocchi M., Roeed K.H., Ryder O.A.,
RA   Searle S., Skow L., Swinburne J.E., Syvaenen A.C., Tozaki T., Valberg S.J.,
RA   Vaudin M., White J.R., Zody M.C., Lander E.S., Lindblad-Toh K.;
RT   "Genome sequence, comparative analysis, and population genetics of the
RT   domestic horse.";
RL   Science 326:865-867(2009).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the SMIM12 family. {ECO:0000305}.
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DR   EMBL; AAWR02028136; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; XP_005607276.1; XM_005607219.2.
DR   RefSeq; XP_014592649.1; XM_014737163.1.
DR   AlphaFoldDB; F6USH3; -.
DR   SMR; F6USH3; -.
DR   STRING; 9796.ENSECAP00000020916; -.
DR   PaxDb; F6USH3; -.
DR   GeneID; 100069744; -.
DR   CTD; 113444; -.
DR   HOGENOM; CLU_160787_0_0_1; -.
DR   InParanoid; F6USH3; -.
DR   OMA; GMDSTQV; -.
DR   OrthoDB; 1641442at2759; -.
DR   TreeFam; TF328614; -.
DR   Proteomes; UP000002281; Unplaced.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR031933; UPF0767.
DR   PANTHER; PTHR28599; PTHR28599; 1.
DR   Pfam; PF15990; UPF0767; 1.
PE   3: Inferred from homology;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..92
FT                   /note="Small integral membrane protein 12"
FT                   /id="PRO_0000414319"
FT   TRANSMEM        12..34
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   92 AA;  10779 MW;  00A053535979EDDD CRC64;
     MWPVLWTVVR TYAPYVTFPV AFVVGAVGYH LEWFIRGKEP QPVEEEKSIS ERREDRKLDE
     LLGKDHTQVV SLKDKLEFAP KAVLNRNRPE KN