ID   SIM12_MYOLU             Reviewed;          92 AA.
AC   G1QDE8;
DT   14-DEC-2011, integrated into UniProtKB/Swiss-Prot.
DT   19-OCT-2011, sequence version 1.
DT   03-AUG-2022, entry version 35.
DE   RecName: Full=Small integral membrane protein 12;
GN   Name=SMIM12;
OS   Myotis lucifugus (Little brown bat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Vespertilionidae;
OC   Myotis.
OX   NCBI_TaxID=59463;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=21993624; DOI=10.1038/nature10530;
RA   Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S.,
RA   Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward L.D., Lowe C.B.,
RA   Holloway A.K., Clamp M., Gnerre S., Alfoldi J., Beal K., Chang J.,
RA   Clawson H., Cuff J., Di Palma F., Fitzgerald S., Flicek P., Guttman M.,
RA   Hubisz M.J., Jaffe D.B., Jungreis I., Kent W.J., Kostka D., Lara M.,
RA   Martins A.L., Massingham T., Moltke I., Raney B.J., Rasmussen M.D.,
RA   Robinson J., Stark A., Vilella A.J., Wen J., Xie X., Zody M.C., Baldwin J.,
RA   Bloom T., Chin C.W., Heiman D., Nicol R., Nusbaum C., Young S.,
RA   Wilkinson J., Worley K.C., Kovar C.L., Muzny D.M., Gibbs R.A., Cree A.,
RA   Dihn H.H., Fowler G., Jhangiani S., Joshi V., Lee S., Lewis L.R.,
RA   Nazareth L.V., Okwuonu G., Santibanez J., Warren W.C., Mardis E.R.,
RA   Weinstock G.M., Wilson R.K., Delehaunty K., Dooling D., Fronik C.,
RA   Fulton L., Fulton B., Graves T., Minx P., Sodergren E., Birney E.,
RA   Margulies E.H., Herrero J., Green E.D., Haussler D., Siepel A., Goldman N.,
RA   Pollard K.S., Pedersen J.S., Lander E.S., Kellis M.;
RT   "A high-resolution map of human evolutionary constraint using 29 mammals.";
RL   Nature 478:476-482(2011).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the SMIM12 family. {ECO:0000305}.
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DR   EMBL; AAPE02028168; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; XP_006094252.1; XM_006094190.2.
DR   RefSeq; XP_006094253.1; XM_006094191.2.
DR   RefSeq; XP_014315943.1; XM_014460457.1.
DR   RefSeq; XP_014315944.1; XM_014460458.1.
DR   AlphaFoldDB; G1QDE8; -.
DR   SMR; G1QDE8; -.
DR   STRING; 59463.ENSMLUP00000021731; -.
DR   PRIDE; G1QDE8; -.
DR   Ensembl; ENSMLUT00000029843; ENSMLUP00000021731; ENSMLUG00000023367.
DR   GeneID; 102441436; -.
DR   KEGG; mlf:102441436; -.
DR   CTD; 113444; -.
DR   eggNOG; ENOG502S2AD; Eukaryota.
DR   GeneTree; ENSGT00390000009435; -.
DR   HOGENOM; CLU_160787_0_0_1; -.
DR   InParanoid; G1QDE8; -.
DR   OMA; GMDSTQV; -.
DR   OrthoDB; 1641442at2759; -.
DR   TreeFam; TF328614; -.
DR   Proteomes; UP000001074; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR031933; UPF0767.
DR   PANTHER; PTHR28599; PTHR28599; 1.
DR   Pfam; PF15990; UPF0767; 1.
PE   3: Inferred from homology;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..92
FT                   /note="Small integral membrane protein 12"
FT                   /id="PRO_0000414321"
FT   TRANSMEM        15..34
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   92 AA;  10813 MW;  51ABF3F953D23BD1 CRC64;
     MWPVFWTVVR TYAPYVTFPV AFVVGAVGYH LEWFIRGKDP QPVEEEKSIS ERREDRKLDE
     LLGKDHTQVL SLKDKLEFAP KAVLNRNRPE KN