ID   SIM14_BOVIN             Reviewed;          99 AA.
AC   Q2KIK3;
DT   12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT   07-MAR-2006, sequence version 1.
DT   03-AUG-2022, entry version 79.
DE   RecName: Full=Small integral membrane protein 14;
GN   Name=SMIM14;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250};
CC       Single-pass membrane protein {ECO:0000250}.
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DR   EMBL; BC112607; AAI12608.1; -; mRNA.
DR   RefSeq; NP_001040008.1; NM_001046543.2.
DR   RefSeq; XP_005207950.1; XM_005207893.3.
DR   AlphaFoldDB; Q2KIK3; -.
DR   STRING; 9913.ENSBTAP00000019303; -.
DR   PaxDb; Q2KIK3; -.
DR   PRIDE; Q2KIK3; -.
DR   Ensembl; ENSBTAT00000019303; ENSBTAP00000019303; ENSBTAG00000014522.
DR   GeneID; 614774; -.
DR   KEGG; bta:614774; -.
DR   CTD; 201895; -.
DR   VEuPathDB; HostDB:ENSBTAG00000014522; -.
DR   VGNC; VGNC:35016; SMIM14.
DR   eggNOG; ENOG502S28C; Eukaryota.
DR   GeneTree; ENSGT00390000018294; -.
DR   HOGENOM; CLU_152284_0_0_1; -.
DR   InParanoid; Q2KIK3; -.
DR   OMA; RQNQNAC; -.
DR   OrthoDB; 1588274at2759; -.
DR   TreeFam; TF314023; -.
DR   Proteomes; UP000009136; Chromosome 6.
DR   Bgee; ENSBTAG00000014522; Expressed in liver and 111 other tissues.
DR   GO; GO:0005783; C:endoplasmic reticulum; ISS:UniProtKB.
DR   GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0001835; P:blastocyst hatching; IEA:Ensembl.
DR   InterPro; IPR020309; Uncharacterised_CD034/YQF4.
DR   PANTHER; PTHR31019; PTHR31019; 1.
DR   Pfam; PF11027; DUF2615; 1.
PE   3: Inferred from homology;
KW   Endoplasmic reticulum; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..99
FT                   /note="Small integral membrane protein 14"
FT                   /id="PRO_0000268815"
FT   TOPO_DOM        1..49
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        50..70
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        71..99
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   REGION          78..99
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   99 AA;  10773 MW;  E954A2260F61D6B4 CRC64;
     MAEGGFDPCE CVCSHEHAMR RLINLLRQSQ SYCTDTECLQ ELPGPSSDNG ISITMILMAW
     MVIAVILFLL RPPNLRGSNL TGKPASPHNG QDPPAPPVD