ID   SIM14_RAT               Reviewed;          99 AA.
AC   Q498C7;
DT   12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT   13-SEP-2005, sequence version 1.
DT   03-AUG-2022, entry version 87.
DE   RecName: Full=Small integral membrane protein 14;
GN   Name=Smim14;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Placenta;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250};
CC       Single-pass membrane protein {ECO:0000250}.
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DR   EMBL; BC100271; AAI00272.1; -; mRNA.
DR   RefSeq; NP_001032881.1; NM_001037792.1.
DR   RefSeq; XP_006251023.1; XM_006250961.3.
DR   AlphaFoldDB; Q498C7; -.
DR   BioGRID; 264622; 1.
DR   STRING; 10116.ENSRNOP00000003552; -.
DR   iPTMnet; Q498C7; -.
DR   PhosphoSitePlus; Q498C7; -.
DR   PaxDb; Q498C7; -.
DR   Ensembl; ENSRNOT00000099960; ENSRNOP00000085533; ENSRNOG00000066377.
DR   GeneID; 364154; -.
DR   KEGG; rno:364154; -.
DR   UCSC; RGD:1311122; rat.
DR   CTD; 201895; -.
DR   RGD; 1311122; Smim14.
DR   eggNOG; ENOG502S7T0; Eukaryota.
DR   GeneTree; ENSGT00390000018294; -.
DR   HOGENOM; CLU_152284_0_0_1; -.
DR   InParanoid; Q498C7; -.
DR   OMA; RQNQNAC; -.
DR   OrthoDB; 1588274at2759; -.
DR   PhylomeDB; Q498C7; -.
DR   TreeFam; TF314023; -.
DR   PRO; PR:Q498C7; -.
DR   Proteomes; UP000002494; Chromosome 14.
DR   Bgee; ENSRNOG00000002553; Expressed in pancreas and 20 other tissues.
DR   Genevisible; Q498C7; RN.
DR   GO; GO:0005783; C:endoplasmic reticulum; ISS:UniProtKB.
DR   GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0001835; P:blastocyst hatching; ISO:RGD.
DR   InterPro; IPR020309; Uncharacterised_CD034/YQF4.
DR   PANTHER; PTHR31019; PTHR31019; 1.
DR   Pfam; PF11027; DUF2615; 1.
PE   3: Inferred from homology;
KW   Endoplasmic reticulum; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..99
FT                   /note="Small integral membrane protein 14"
FT                   /id="PRO_0000268819"
FT   TOPO_DOM        1..49
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        50..70
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        71..99
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   REGION          77..99
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   99 AA;  10684 MW;  124D5D786B36AECA CRC64;
     MAEGGFDPCE CICSHEHAMR RLINLLRQSQ SYCTDTECLR ELPGPSGDSG ISITVILMAW
     MVIAVLLFLL RPPNLRGSSL PGKPSSPHSG QDPPAPPVD