BH117_ARATH
ID BH117_ARATH Reviewed; 252 AA.
AC Q9LRJ4; C0SVC5;
DT 16-DEC-2008, integrated into UniProtKB/Swiss-Prot.
DT 16-DEC-2008, sequence version 2.
DT 25-MAY-2022, entry version 116.
DE RecName: Full=Transcription factor bHLH117;
DE AltName: Full=Basic helix-loop-helix protein 117;
DE Short=AtbHLH117;
DE Short=bHLH 117;
DE AltName: Full=Transcription factor EN 140;
DE AltName: Full=bHLH transcription factor bHLH117;
GN Name=BHLH117; Synonyms=EN140; OrderedLocusNames=At3g22100;
GN ORFNames=MZN24.31;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10819329; DOI=10.1093/dnares/7.2.131;
RA Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 3. I. Sequence
RT features of the regions of 4,504,864 bp covered by sixty P1 and TAC
RT clones.";
RL DNA Res. 7:131-135(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Fujita M., Mizukado S., Seki M., Shinozaki K., Mitsuda N., Takiguchi Y.,
RA Takagi M.;
RT "ORF cloning and analysis of Arabidopsis transcription factor genes.";
RL Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=12679534; DOI=10.1093/molbev/msg088;
RA Heim M.A., Jakoby M., Werber M., Martin C., Weisshaar B., Bailey P.C.;
RT "The basic helix-loop-helix transcription factor family in plants: a
RT genome-wide study of protein structure and functional diversity.";
RL Mol. Biol. Evol. 20:735-747(2003).
RN [5]
RP GENE FAMILY.
RX PubMed=12897250; DOI=10.1105/tpc.013839;
RA Toledo-Ortiz G., Huq E., Quail P.H.;
RT "The Arabidopsis basic/helix-loop-helix transcription factor family.";
RL Plant Cell 15:1749-1770(2003).
RN [6]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=14600211; DOI=10.1105/tpc.151140;
RA Bailey P.C., Martin C., Toledo-Ortiz G., Quail P.H., Huq E., Heim M.A.,
RA Jakoby M., Werber M., Weisshaar B.;
RT "Update on the basic helix-loop-helix transcription factor gene family in
RT Arabidopsis thaliana.";
RL Plant Cell 15:2497-2502(2003).
CC -!- SUBUNIT: Homodimer. {ECO:0000305}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAB01396.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AB028622; BAB01396.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002686; AEE76589.1; -; Genomic_DNA.
DR EMBL; AB493628; BAH30466.1; -; mRNA.
DR RefSeq; NP_188848.1; NM_113106.2.
DR AlphaFoldDB; Q9LRJ4; -.
DR SMR; Q9LRJ4; -.
DR PaxDb; Q9LRJ4; -.
DR PRIDE; Q9LRJ4; -.
DR EnsemblPlants; AT3G22100.1; AT3G22100.1; AT3G22100.
DR GeneID; 821772; -.
DR Gramene; AT3G22100.1; AT3G22100.1; AT3G22100.
DR KEGG; ath:AT3G22100; -.
DR Araport; AT3G22100; -.
DR TAIR; locus:2095612; AT3G22100.
DR eggNOG; ENOG502S14F; Eukaryota.
DR HOGENOM; CLU_069236_0_0_1; -.
DR InParanoid; Q9LRJ4; -.
DR OMA; PASQYVH; -.
DR OrthoDB; 1442337at2759; -.
DR PRO; PR:Q9LRJ4; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q9LRJ4; baseline and differential.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR CDD; cd11393; bHLH_AtbHLH_like; 1.
DR Gene3D; 4.10.280.10; -; 1.
DR InterPro; IPR045239; bHLH95_bHLH.
DR InterPro; IPR011598; bHLH_dom.
DR InterPro; IPR036638; HLH_DNA-bd_sf.
DR InterPro; IPR045843; IND-like.
DR PANTHER; PTHR45914; PTHR45914; 1.
DR Pfam; PF00010; HLH; 1.
DR SUPFAM; SSF47459; SSF47459; 1.
DR PROSITE; PS50888; BHLH; 1.
PE 2: Evidence at transcript level;
KW DNA-binding; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..252
FT /note="Transcription factor bHLH117"
FT /id="PRO_0000358802"
FT DOMAIN 130..179
FT /note="bHLH"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00981"
FT REGION 103..141
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 115..137
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 252 AA; 28341 MW; 896EBEF42F1B7AAB CRC64;
METPAYDFDS LTDLPPLPPS DFTPSNAFTF PDHNLDFSFL DSTLSLLNRH HLSESTRLEQ
IFYDSTHTQL FHNDDTTTTT TPFLHLPDLK SIDAVEEPTT MKLFPSLSPP LPAAKRQKLN
STSSSTTSGS PTASNDGGII TKRRKISDKI RSLEKLMPWE RKMNLAMTLE ESHKYIKFLQ
SQIASLRWMP LESVYNTAGE VGETDLLKSL TRQQILQVLA NSPGSRNVLS SRGVCVFSYE
QLLSLKTMSR NL
