ID   SIM26_HUMAN             Reviewed;          95 AA.
AC   A0A096LP01;
DT   05-JUL-2017, integrated into UniProtKB/Swiss-Prot.
DT   26-NOV-2014, sequence version 1.
DT   03-AUG-2022, entry version 45.
DE   RecName: Full=Small integral membrane protein 26 {ECO:0000312|HGNC:HGNC:43430};
GN   Name=SMIM26 {ECO:0000312|HGNC:HGNC:43430};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=11780052; DOI=10.1038/414865a;
RA   Deloukas P., Matthews L.H., Ashurst J.L., Burton J., Gilbert J.G.R.,
RA   Jones M., Stavrides G., Almeida J.P., Babbage A.K., Bagguley C.L.,
RA   Bailey J., Barlow K.F., Bates K.N., Beard L.M., Beare D.M., Beasley O.P.,
RA   Bird C.P., Blakey S.E., Bridgeman A.M., Brown A.J., Buck D., Burrill W.D.,
RA   Butler A.P., Carder C., Carter N.P., Chapman J.C., Clamp M., Clark G.,
RA   Clark L.N., Clark S.Y., Clee C.M., Clegg S., Cobley V.E., Collier R.E.,
RA   Connor R.E., Corby N.R., Coulson A., Coville G.J., Deadman R., Dhami P.D.,
RA   Dunn M., Ellington A.G., Frankland J.A., Fraser A., French L., Garner P.,
RA   Grafham D.V., Griffiths C., Griffiths M.N.D., Gwilliam R., Hall R.E.,
RA   Hammond S., Harley J.L., Heath P.D., Ho S., Holden J.L., Howden P.J.,
RA   Huckle E., Hunt A.R., Hunt S.E., Jekosch K., Johnson C.M., Johnson D.,
RA   Kay M.P., Kimberley A.M., King A., Knights A., Laird G.K., Lawlor S.,
RA   Lehvaeslaiho M.H., Leversha M.A., Lloyd C., Lloyd D.M., Lovell J.D.,
RA   Marsh V.L., Martin S.L., McConnachie L.J., McLay K., McMurray A.A.,
RA   Milne S.A., Mistry D., Moore M.J.F., Mullikin J.C., Nickerson T.,
RA   Oliver K., Parker A., Patel R., Pearce T.A.V., Peck A.I.,
RA   Phillimore B.J.C.T., Prathalingam S.R., Plumb R.W., Ramsay H., Rice C.M.,
RA   Ross M.T., Scott C.E., Sehra H.K., Shownkeen R., Sims S., Skuce C.D.,
RA   Smith M.L., Soderlund C., Steward C.A., Sulston J.E., Swann R.M.,
RA   Sycamore N., Taylor R., Tee L., Thomas D.W., Thorpe A., Tracey A.,
RA   Tromans A.C., Vaudin M., Wall M., Wallis J.M., Whitehead S.L.,
RA   Whittaker P., Willey D.L., Williams L., Williams S.A., Wilming L.,
RA   Wray P.W., Hubbard T., Durbin R.M., Bentley D.R., Beck S., Rogers J.;
RT   "The DNA sequence and comparative analysis of human chromosome 20.";
RL   Nature 414:865-871(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000255}; Single-pass membrane
CC       protein {ECO:0000255}.
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DR   EMBL; AL121900; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; BC015983; -; NOT_ANNOTATED_CDS; mRNA.
DR   CCDS; CCDS86936.1; -.
DR   AlphaFoldDB; A0A096LP01; -.
DR   STRING; 9606.ENSP00000485316; -.
DR   BioMuta; SMIM26; -.
DR   EPD; A0A096LP01; -.
DR   jPOST; A0A096LP01; -.
DR   MassIVE; A0A096LP01; -.
DR   PaxDb; A0A096LP01; -.
DR   PeptideAtlas; A0A096LP01; -.
DR   Antibodypedia; 77488; 3 antibodies from 3 providers.
DR   Ensembl; ENST00000411646.2; ENSP00000485316.2; ENSG00000232388.5.
DR   MANE-Select; ENST00000411646.2; ENSP00000485316.2; NM_001348957.2; NP_001335886.1.
DR   UCSC; uc002wrd.5; human.
DR   GeneCards; SMIM26; -.
DR   HGNC; HGNC:43430; SMIM26.
DR   HPA; ENSG00000232388; Low tissue specificity.
DR   neXtProt; NX_A0A096LP01; -.
DR   VEuPathDB; HostDB:ENSG00000232388; -.
DR   eggNOG; ENOG502T084; Eukaryota.
DR   GeneTree; ENSGT00860000134050; -.
DR   HOGENOM; CLU_2385584_0_0_1; -.
DR   OMA; SWYRRMS; -.
DR   Pharos; A0A096LP01; Tdark.
DR   PRO; PR:A0A096LP01; -.
DR   Proteomes; UP000005640; Chromosome 20.
DR   RNAct; A0A096LP01; protein.
DR   Bgee; ENSG00000232388; Expressed in quadriceps femoris and 102 other tissues.
DR   ExpressionAtlas; A0A096LP01; baseline and differential.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR038831; SMIM26.
DR   PANTHER; PTHR40386; PTHR40386; 1.
PE   3: Inferred from homology;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..95
FT                   /note="Small integral membrane protein 26"
FT                   /id="PRO_0000440652"
FT   TRANSMEM        13..35
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   95 AA;  10908 MW;  DEC57BBD71737916 CRC64;
     MYRNEFTAWY RRMSVVYGIG TWSVLGSLLY YSRTMAKSSV DQKDGSASEV PSELSERPKG
     FYVETVVTYK EDFVPNTEKI LNYWKSWTGG PGTEP