SIM29_MOUSE
ID SIM29_MOUSE Reviewed; 102 AA.
AC Q8R043; Q3V2N7;
DT 02-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT 23-MAY-2018, sequence version 2.
DT 03-AUG-2022, entry version 84.
DE RecName: Full=Small integral membrane protein 29;
DE AltName: Full=Uncharacterized protein SMIM29;
GN Name=Smim29;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Brain, and Testis;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J;
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Thymus;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000255}; Single-pass membrane
CC protein {ECO:0000255}.
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DR EMBL; AK131593; BAE20706.1; -; mRNA.
DR EMBL; AK131681; BAE20760.1; -; mRNA.
DR EMBL; AC127341; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; BC028464; AAH28464.2; -; mRNA.
DR CCDS; CCDS37521.1; -.
DR RefSeq; NP_001002895.2; NM_001002895.2.
DR RefSeq; XP_006523476.1; XM_006523413.3.
DR RefSeq; XP_011244542.1; XM_011246240.2.
DR AlphaFoldDB; Q8R043; -.
DR SMR; Q8R043; -.
DR GlyGen; Q8R043; 1 site.
DR PRIDE; Q8R043; -.
DR ProteomicsDB; 330858; -.
DR Ensembl; ENSMUST00000145183; ENSMUSP00000156249; ENSMUSG00000062753.
DR Ensembl; ENSMUST00000154473; ENSMUSP00000116199; ENSMUSG00000062753.
DR Ensembl; ENSMUST00000232276; ENSMUSP00000156204; ENSMUSG00000062753.
DR GeneID; 106672; -.
DR KEGG; mmu:106672; -.
DR UCSC; uc008bpe.1; mouse.
DR MGI; MGI:2146839; AI413582.
DR VEuPathDB; HostDB:ENSMUSG00000062753; -.
DR eggNOG; ENOG502S4I5; Eukaryota.
DR GeneTree; ENSGT00410000025882; -.
DR HOGENOM; CLU_179422_0_0_1; -.
DR OMA; MMYIQKK; -.
DR OrthoDB; 1453896at2759; -.
DR TreeFam; TF332764; -.
DR BioGRID-ORCS; 106672; 5 hits in 72 CRISPR screens.
DR ChiTaRS; AI413582; mouse.
DR PRO; PR:Q8R043; -.
DR Proteomes; UP000000589; Chromosome 17.
DR RNAct; Q8R043; protein.
DR Bgee; ENSMUSG00000062753; Expressed in dentate gyrus of hippocampal formation granule cell and 177 other tissues.
DR ExpressionAtlas; Q8R043; baseline and differential.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR InterPro; IPR043239; SMIM29.
DR PANTHER; PTHR47730; PTHR47730; 1.
PE 3: Inferred from homology;
KW Glycoprotein; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..102
FT /note="Small integral membrane protein 29"
FT /id="PRO_0000019540"
FT TRANSMEM 21..41
FT /note="Helical"
FT /evidence="ECO:0000255"
FT CARBOHYD 3
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 102 AA; 11553 MW; DC3E15956BBB4E90 CRC64;
MSNTTVPNAP QANSDSMVGY VLGPFFLITL VGVVVAVVMY VQKKKRVDRL RHHLLPMYSY
DPAEELQEAE QELLSDVGDP KVVHGWQSSY QHKRMPLLDI KT
