BH120_ARATH
ID BH120_ARATH Reviewed; 204 AA.
AC Q9FLI0; C0SVT6;
DT 16-DEC-2008, integrated into UniProtKB/Swiss-Prot.
DT 22-SEP-2009, sequence version 2.
DT 03-AUG-2022, entry version 118.
DE RecName: Full=Transcription factor bHLH120;
DE AltName: Full=Basic helix-loop-helix protein 120;
DE Short=AtbHLH120;
DE Short=bHLH 120;
DE AltName: Full=Transcription factor EN 4;
DE AltName: Full=bHLH transcription factor bHLH120;
GN Name=BHLH120; Synonyms=EN4; OrderedLocusNames=At5g51790; ORFNames=MIO24.8;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=9628582; DOI=10.1093/dnares/5.1.41;
RA Sato S., Kaneko T., Kotani H., Nakamura Y., Asamizu E., Miyajima N.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. IV. Sequence
RT features of the regions of 1,456,315 bp covered by nineteen physically
RT assigned P1 and TAC clones.";
RL DNA Res. 5:41-54(1998).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Fujita M., Mizukado S., Seki M., Shinozaki K., Mitsuda N., Takiguchi Y.,
RA Takagi M.;
RT "ORF cloning and analysis of Arabidopsis transcription factor genes.";
RL Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=12679534; DOI=10.1093/molbev/msg088;
RA Heim M.A., Jakoby M., Werber M., Martin C., Weisshaar B., Bailey P.C.;
RT "The basic helix-loop-helix transcription factor family in plants: a
RT genome-wide study of protein structure and functional diversity.";
RL Mol. Biol. Evol. 20:735-747(2003).
RN [5]
RP GENE FAMILY.
RX PubMed=12897250; DOI=10.1105/tpc.013839;
RA Toledo-Ortiz G., Huq E., Quail P.H.;
RT "The Arabidopsis basic/helix-loop-helix transcription factor family.";
RL Plant Cell 15:1749-1770(2003).
RN [6]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=14600211; DOI=10.1105/tpc.151140;
RA Bailey P.C., Martin C., Toledo-Ortiz G., Quail P.H., Huq E., Heim M.A.,
RA Jakoby M., Werber M., Weisshaar B.;
RT "Update on the basic helix-loop-helix transcription factor gene family in
RT Arabidopsis thaliana.";
RL Plant Cell 15:2497-2502(2003).
CC -!- SUBUNIT: Homodimer. {ECO:0000305}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAB11248.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AB010074; BAB11248.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002688; AED96126.1; -; Genomic_DNA.
DR EMBL; AB493789; BAH30627.1; -; mRNA.
DR RefSeq; NP_199992.2; NM_124558.3.
DR AlphaFoldDB; Q9FLI0; -.
DR SMR; Q9FLI0; -.
DR BioGRID; 20498; 9.
DR IntAct; Q9FLI0; 9.
DR STRING; 3702.AT5G51790.1; -.
DR PaxDb; Q9FLI0; -.
DR PRIDE; Q9FLI0; -.
DR EnsemblPlants; AT5G51790.1; AT5G51790.1; AT5G51790.
DR GeneID; 835253; -.
DR Gramene; AT5G51790.1; AT5G51790.1; AT5G51790.
DR KEGG; ath:AT5G51790; -.
DR Araport; AT5G51790; -.
DR TAIR; locus:2165321; AT5G51790.
DR eggNOG; ENOG502S1BU; Eukaryota.
DR HOGENOM; CLU_094733_1_1_1; -.
DR InParanoid; Q9FLI0; -.
DR OMA; IVTVKEC; -.
DR PhylomeDB; Q9FLI0; -.
DR PRO; PR:Q9FLI0; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9FLI0; baseline and differential.
DR GO; GO:0090575; C:RNA polymerase II transcription regulator complex; IBA:GO_Central.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0000977; F:RNA polymerase II transcription regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:TAIR.
DR Gene3D; 4.10.280.10; -; 1.
DR InterPro; IPR011598; bHLH_dom.
DR InterPro; IPR036638; HLH_DNA-bd_sf.
DR InterPro; IPR015660; MASH1/Ascl1a-like.
DR PANTHER; PTHR13935; PTHR13935; 1.
DR Pfam; PF00010; HLH; 1.
DR SUPFAM; SSF47459; SSF47459; 1.
DR PROSITE; PS50888; BHLH; 1.
PE 2: Evidence at transcript level;
KW DNA-binding; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..204
FT /note="Transcription factor bHLH120"
FT /id="PRO_0000358805"
FT DOMAIN 26..78
FT /note="bHLH"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00981"
FT REGION 1..27
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 93..116
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 12..27
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 100..116
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 204 AA; 22995 MW; 851FB95D97551C60 CRC64;
MNPSNNPKKT RHQSHMPQER DETKKEKKLL HRNIERQRRQ EMAILFASLR SQLPLKYIKG
KRAMSDHVNG AVSFIKDTQT RIKDLSARRD ELKREIGDPT SLTGSGSGSG SSRSEPASVM
VQPCVSGFEV VVSSLASGLE AWPLSRVLEV LHGQGLEVIS SLTARVNERL MYTIQVEVNS
FDCFDLAWLQ QKLIEQLVLS TTRH
