SIM36_HUMAN
ID SIM36_HUMAN Reviewed; 93 AA.
AC A0A1B0GVT2;
DT 28-FEB-2018, integrated into UniProtKB/Swiss-Prot.
DT 05-OCT-2016, sequence version 1.
DT 03-AUG-2022, entry version 21.
DE RecName: Full=Small integral membrane protein 36 {ECO:0000305};
GN Name=SMIM36 {ECO:0000312|HGNC:HGNC:53654};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16625196; DOI=10.1038/nature04689;
RA Zody M.C., Garber M., Adams D.J., Sharpe T., Harrow J., Lupski J.R.,
RA Nicholson C., Searle S.M., Wilming L., Young S.K., Abouelleil A.,
RA Allen N.R., Bi W., Bloom T., Borowsky M.L., Bugalter B.E., Butler J.,
RA Chang J.L., Chen C.-K., Cook A., Corum B., Cuomo C.A., de Jong P.J.,
RA DeCaprio D., Dewar K., FitzGerald M., Gilbert J., Gibson R., Gnerre S.,
RA Goldstein S., Grafham D.V., Grocock R., Hafez N., Hagopian D.S., Hart E.,
RA Norman C.H., Humphray S., Jaffe D.B., Jones M., Kamal M., Khodiyar V.K.,
RA LaButti K., Laird G., Lehoczky J., Liu X., Lokyitsang T., Loveland J.,
RA Lui A., Macdonald P., Major J.E., Matthews L., Mauceli E., McCarroll S.A.,
RA Mihalev A.H., Mudge J., Nguyen C., Nicol R., O'Leary S.B., Osoegawa K.,
RA Schwartz D.C., Shaw-Smith C., Stankiewicz P., Steward C., Swarbreck D.,
RA Venkataraman V., Whittaker C.A., Yang X., Zimmer A.R., Bradley A.,
RA Hubbard T., Birren B.W., Rogers J., Lander E.S., Nusbaum C.;
RT "DNA sequence of human chromosome 17 and analysis of rearrangement in the
RT human lineage.";
RL Nature 440:1045-1049(2006).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000255}; Single-pass membrane
CC protein {ECO:0000255}.
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DR EMBL; AC006269; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A1B0GVT2; -.
DR SMR; A0A1B0GVT2; -.
DR BioMuta; ENSG00000261873; -.
DR MassIVE; A0A1B0GVT2; -.
DR PeptideAtlas; A0A1B0GVT2; -.
DR Ensembl; ENST00000636752.1; ENSP00000490644.1; ENSG00000261873.2.
DR GeneCards; SMIM36; -.
DR HGNC; HGNC:53654; SMIM36.
DR HPA; ENSG00000261873; Tissue enriched (retina).
DR neXtProt; NX_A0A1B0GVT2; -.
DR VEuPathDB; HostDB:ENSG00000261873; -.
DR GeneTree; ENSGT00980000198588; -.
DR OMA; SIHLVVM; -.
DR ChiTaRS; SMIM36; human.
DR Pharos; A0A1B0GVT2; Tdark.
DR PRO; PR:A0A1B0GVT2; -.
DR Proteomes; UP000005640; Chromosome 17.
DR RNAct; A0A1B0GVT2; protein.
DR Bgee; ENSG00000261873; Expressed in right testis and 58 other tissues.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
PE 3: Inferred from homology;
KW Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT CHAIN 1..93
FT /note="Small integral membrane protein 36"
FT /id="PRO_0000443403"
FT TRANSMEM 14..34
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 73..93
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 93 AA; 10135 MW; 2C8889B5FF4B993F CRC64;
MEFYLEIDPV TLNLIILVAS YVILLLVFLI SCVLYDCRGK DPSKEYAPEA TLEAQPSIRL
VVMHPSVAGP HWPKGPGLSL GDPAPLGKKS TMV