SINR_BACLI
ID SINR_BACLI Reviewed; 111 AA.
AC P22753;
DT 01-AUG-1991, integrated into UniProtKB/Swiss-Prot.
DT 01-AUG-1991, sequence version 1.
DT 25-MAY-2022, entry version 99.
DE RecName: Full=HTH-type transcriptional regulator SinR;
GN Name=sinR; Synonyms=flaL, sin;
OS Bacillus licheniformis.
OC Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=1402;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=FD0120;
RX PubMed=2121898; DOI=10.1099/00221287-136-7-1223;
RA Sekiguchi J., Ohsu H., Kuroda A., Moriyama H., Akamatsu T.;
RT "Nucleotide sequences of the Bacillus subtilis flaD locus and a B.
RT licheniformis homologue affecting the autolysin level and flagellation.";
RL J. Gen. Microbiol. 136:1223-1230(1990).
CC -!- FUNCTION: Affects autolysin level and flagellation.
CC -!- SUBUNIT: Homotetramer. Also associates with SinI.
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DR EMBL; M60287; AAA22439.1; -; Genomic_DNA.
DR PIR; B45824; B45824.
DR AlphaFoldDB; P22753; -.
DR SMR; P22753; -.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0044781; P:bacterial-type flagellum organization; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR CDD; cd00093; HTH_XRE; 1.
DR Gene3D; 1.10.260.40; -; 1.
DR InterPro; IPR001387; Cro/C1-type_HTH.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR010981; SinR/SinI_dimer_dom.
DR InterPro; IPR036281; SinR/SinI_dimer_dom_sf.
DR Pfam; PF01381; HTH_3; 1.
DR Pfam; PF08671; SinI; 1.
DR SMART; SM00530; HTH_XRE; 1.
DR SUPFAM; SSF47406; SSF47406; 1.
DR SUPFAM; SSF47413; SSF47413; 1.
DR PROSITE; PS50943; HTH_CROC1; 1.
DR PROSITE; PS51500; SIN; 1.
PE 4: Predicted;
KW Activator; Bacterial flagellum biogenesis; DNA-binding; Repressor;
KW Transcription; Transcription regulation.
FT CHAIN 1..111
FT /note="HTH-type transcriptional regulator SinR"
FT /id="PRO_0000149737"
FT DOMAIN 6..61
FT /note="HTH cro/C1-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00257"
FT DOMAIN 65..103
FT /note="Sin"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00833"
FT DNA_BIND 17..36
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00257"
SQ SEQUENCE 111 AA; 12963 MW; 4A2E14F89EF48ACF CRC64;
MIGQRIKQYR KEKGYSLSEL AEKAGVAKSY LSSIERNLQT NPSIQFLEKV SAVLDVSVHT
LLNEKDETEY DGQLDSEWEN LVRDAMASGV SKKQFREFLD YQKWKKRQEK E