ID   SIP11_MAIZE             Reviewed;         245 AA.
AC   Q9ATM3;
DT   01-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2001, sequence version 1.
DT   25-MAY-2022, entry version 101.
DE   RecName: Full=Aquaporin SIP1-1;
DE   AltName: Full=Small basic intrinsic protein 1-1;
DE   AltName: Full=ZmSIP1-1;
DE   AltName: Full=ZmSIP1;1;
GN   Name=SIP1-1; Synonyms=SIP1A;
OS   Zea mays (Maize).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC   Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea.
OX   NCBI_TaxID=4577;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], GENE FAMILY, AND NOMENCLATURE.
RC   STRAIN=cv. B73;
RX   PubMed=11244102; DOI=10.1104/pp.125.3.1206;
RA   Chaumont F., Barrieu F., Wojcik E., Chrispeels M.J., Jung R.;
RT   "Aquaporins constitute a large and highly divergent protein family in
RT   maize.";
RL   Plant Physiol. 125:1206-1215(2001).
CC   -!- FUNCTION: Aquaporins facilitate the transport of water and small
CC       neutral solutes across cell membranes. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- DOMAIN: Aquaporins contain two tandem repeats each containing three
CC       membrane-spanning domains and a pore-forming loop with the signature
CC       motif Asn-Pro-Ala (NPA).
CC   -!- SIMILARITY: Belongs to the MIP/aquaporin (TC 1.A.8) family. SIP (TC
CC       1.A.8.10) subfamily. {ECO:0000305}.
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DR   EMBL; AF326497; AAK26764.1; -; mRNA.
DR   RefSeq; NP_001105514.1; NM_001112044.1.
DR   AlphaFoldDB; Q9ATM3; -.
DR   SMR; Q9ATM3; -.
DR   STRING; 4577.GRMZM2G113470_P01; -.
DR   PaxDb; Q9ATM3; -.
DR   EnsemblPlants; Zm00001eb167790_T001; Zm00001eb167790_P001; Zm00001eb167790.
DR   GeneID; 542494; -.
DR   Gramene; Zm00001eb167790_T001; Zm00001eb167790_P001; Zm00001eb167790.
DR   KEGG; zma:542494; -.
DR   MaizeGDB; 403431; -.
DR   eggNOG; KOG0223; Eukaryota.
DR   HOGENOM; CLU_100006_0_0_1; -.
DR   OrthoDB; 1487748at2759; -.
DR   Proteomes; UP000007305; Chromosome 4.
DR   ExpressionAtlas; Q9ATM3; baseline and differential.
DR   Genevisible; Q9ATM3; ZM.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015250; F:water channel activity; IEA:InterPro.
DR   Gene3D; 1.20.1080.10; -; 1.
DR   InterPro; IPR023271; Aquaporin-like.
DR   InterPro; IPR000425; MIP.
DR   InterPro; IPR044222; SIP1-1/2-like.
DR   PANTHER; PTHR46739; PTHR46739; 1.
DR   Pfam; PF00230; MIP; 1.
DR   PRINTS; PR00783; MINTRINSICP.
DR   SUPFAM; SSF81338; SSF81338; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Reference proteome; Repeat; Transmembrane; Transmembrane helix;
KW   Transport.
FT   CHAIN           1..245
FT                   /note="Aquaporin SIP1-1"
FT                   /id="PRO_0000286039"
FT   TRANSMEM        14..34
FT                   /note="Helical; Name=1"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        55..75
FT                   /note="Helical; Name=2"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        100..120
FT                   /note="Helical; Name=3"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        138..158
FT                   /note="Helical; Name=4"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        164..184
FT                   /note="Helical; Name=5"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        213..233
FT                   /note="Helical; Name=6"
FT                   /evidence="ECO:0000255"
FT   MOTIF           76..78
FT                   /note="NPA 1"
FT                   /evidence="ECO:0000250"
FT   MOTIF           191..193
FT                   /note="NPA 2"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   245 AA;  25623 MW;  8A74FE8088519C10 CRC64;
     MAMGATVRAA AADAVVTFLW VLCASALGAS TAAVTSYLGV QEGAGHYALL VTTSLLSVLL
     FTFDLLCGAL GGASFNPTDF AASYAAGLDS PSLFSVALRF PAQAAGAVGG ALAISELMPA
     QYKHTLAGPS LKVDPHTGAL AEGVLTFVIT LTVLWVIVKG PRNVILKTLL LSTSIVSVIL
     AGAEYTGPSM NPANAFGWAY VNNWHNTWEQ LYVYWICPFI GAMLAGWIFR VVFLPPAPKP
     KTKKA