SIP18_YEAST
ID SIP18_YEAST Reviewed; 79 AA.
AC P50263; D6VZZ7;
DT 01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-1996, sequence version 1.
DT 03-AUG-2022, entry version 114.
DE RecName: Full=Protein SIP18;
GN Name=SIP18; OrderedLocusNames=YMR175W; ORFNames=YM8010.05;
OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=559292;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=DBY939;
RX PubMed=8801420; DOI=10.1111/j.1365-2958.1995.mmi_17040653.x;
RA Miralles V.J., Serrano R.;
RT "A genomic locus in Saccharomyces cerevisiae with four genes up-regulated
RT by osmotic stress.";
RL Mol. Microbiol. 17:653-662(1995).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=9169872;
RA Bowman S., Churcher C.M., Badcock K., Brown D., Chillingworth T.,
RA Connor R., Dedman K., Devlin K., Gentles S., Hamlin N., Hunt S., Jagels K.,
RA Lye G., Moule S., Odell C., Pearson D., Rajandream M.A., Rice P.,
RA Skelton J., Walsh S.V., Whitehead S., Barrell B.G.;
RT "The nucleotide sequence of Saccharomyces cerevisiae chromosome XIII.";
RL Nature 387:90-93(1997).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=24374639; DOI=10.1534/g3.113.008995;
RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL G3 (Bethesda) 4:389-398(2014).
RN [4]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=17322287; DOI=10.1101/gr.6037607;
RA Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F.,
RA Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J.,
RA Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J.,
RA Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D.,
RA LaBaer J.;
RT "Approaching a complete repository of sequence-verified protein-encoding
RT clones for Saccharomyces cerevisiae.";
RL Genome Res. 17:536-543(2007).
RN [5]
RP LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
RX PubMed=14562106; DOI=10.1038/nature02046;
RA Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N.,
RA O'Shea E.K., Weissman J.S.;
RT "Global analysis of protein expression in yeast.";
RL Nature 425:737-741(2003).
CC -!- MISCELLANEOUS: Present with 2300 molecules/cell in log phase SD medium.
CC {ECO:0000269|PubMed:14562106}.
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DR EMBL; X85988; CAA59976.1; -; Genomic_DNA.
DR EMBL; Z49808; CAA89908.1; -; Genomic_DNA.
DR EMBL; AY558518; AAS56844.1; -; Genomic_DNA.
DR EMBL; BK006946; DAA10071.1; -; Genomic_DNA.
DR PIR; S70188; S70188.
DR RefSeq; NP_013900.1; NM_001182681.1.
DR AlphaFoldDB; P50263; -.
DR BioGRID; 35353; 24.
DR STRING; 4932.YMR175W; -.
DR iPTMnet; P50263; -.
DR PaxDb; P50263; -.
DR PRIDE; P50263; -.
DR TopDownProteomics; P50263; -.
DR EnsemblFungi; YMR175W_mRNA; YMR175W; YMR175W.
DR GeneID; 855213; -.
DR KEGG; sce:YMR175W; -.
DR SGD; S000004787; SIP18.
DR VEuPathDB; FungiDB:YMR175W; -.
DR HOGENOM; CLU_2607358_0_0_1; -.
DR BioCyc; YEAST:G3O-32863-MON; -.
DR PRO; PR:P50263; -.
DR Proteomes; UP000002311; Chromosome XIII.
DR RNAct; P50263; protein.
DR GO; GO:0005737; C:cytoplasm; IDA:SGD.
DR GO; GO:0005543; F:phospholipid binding; IDA:SGD.
DR GO; GO:0042631; P:cellular response to water deprivation; IMP:SGD.
PE 1: Evidence at protein level;
KW Reference proteome.
FT CHAIN 1..79
FT /note="Protein SIP18"
FT /id="PRO_0000097764"
FT REGION 1..79
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 12..40
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 47..48
FT /note="EG -> K (in Ref. 1; CAA59976)"
FT /evidence="ECO:0000305"
FT CONFLICT 76..79
FT /note="NMKK -> HENMYVFGALTKSSYFFNGLFMNCLCLCSLYSKSISAYFSEFSS
FT TNIYKSYLRLPSVLYYVCMMHTMMPNQLDAVGIQSSESLLM (in Ref. 1;
FT CAA59976)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 79 AA; 8874 MW; 348BDBB41C7B34C3 CRC64;
MSNMMNKFAE KLQGNDDSHQ KGKNAKSSNK ERDDMNMDMG MGHDQSEGGM KMGHDQSGTK
MNAGRGIAND WKTYENMKK
