SIP21_ORYSJ
ID SIP21_ORYSJ Reviewed; 250 AA.
AC Q10M80; A0A0P0VXM0;
DT 01-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT 22-AUG-2006, sequence version 1.
DT 03-AUG-2022, entry version 102.
DE RecName: Full=Aquaporin SIP2-1;
DE AltName: Full=OsSIP2;1;
DE AltName: Full=Small basic intrinsic protein 2-1;
GN Name=SIP2-1; OrderedLocusNames=Os03g0320000, LOC_Os03g20410;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16109971; DOI=10.1101/gr.3869505;
RG The rice chromosome 3 sequencing consortium;
RA Buell C.R., Yuan Q., Ouyang S., Liu J., Zhu W., Wang A., Maiti R., Haas B.,
RA Wortman J., Pertea M., Jones K.M., Kim M., Overton L., Tsitrin T.,
RA Fadrosh D., Bera J., Weaver B., Jin S., Johri S., Reardon M., Webb K.,
RA Hill J., Moffat K., Tallon L., Van Aken S., Lewis M., Utterback T.,
RA Feldblyum T., Zismann V., Iobst S., Hsiao J., de Vazeille A.R.,
RA Salzberg S.L., White O., Fraser C.M., Yu Y., Kim H., Rambo T., Currie J.,
RA Collura K., Kernodle-Thompson S., Wei F., Kudrna K., Ammiraju J.S.S.,
RA Luo M., Goicoechea J.L., Wing R.A., Henry D., Oates R., Palmer M.,
RA Pries G., Saski C., Simmons J., Soderlund C., Nelson W., de la Bastide M.,
RA Spiegel L., Nascimento L., Huang E., Preston R., Zutavern T., Palmer L.,
RA O'Shaughnessy A., Dike S., McCombie W.R., Minx P., Cordum H., Wilson R.,
RA Jin W., Lee H.R., Jiang J., Jackson S.;
RT "Sequence, annotation, and analysis of synteny between rice chromosome 3
RT and diverged grass species.";
RL Genome Res. 15:1284-1291(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
RN [6]
RP NOMENCLATURE, AND TISSUE SPECIFICITY.
RX PubMed=16033806; DOI=10.1093/pcp/pci172;
RA Sakurai J., Ishikawa F., Yamaguchi T., Uemura M., Maeshima M.;
RT "Identification of 33 rice aquaporin genes and analysis of their expression
RT and function.";
RL Plant Cell Physiol. 46:1568-1577(2005).
CC -!- FUNCTION: Aquaporins facilitate the transport of water and small
CC neutral solutes across cell membranes. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- TISSUE SPECIFICITY: Expressed in leaves and anthers, and at lower
CC levels in roots. {ECO:0000269|PubMed:16033806}.
CC -!- DOMAIN: Aquaporins contain two tandem repeats each containing three
CC membrane-spanning domains and a pore-forming loop with the signature
CC motif Asn-Pro-Ala (NPA).
CC -!- SIMILARITY: Belongs to the MIP/aquaporin (TC 1.A.8) family. SIP (TC
CC 1.A.8.10) subfamily. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AK071190; Type=Frameshift; Evidence={ECO:0000305};
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DR EMBL; DP000009; ABF95655.1; -; Genomic_DNA.
DR EMBL; AP008209; BAF11864.1; -; Genomic_DNA.
DR EMBL; AP014959; BAS83928.1; -; Genomic_DNA.
DR EMBL; AK071190; -; NOT_ANNOTATED_CDS; mRNA.
DR AlphaFoldDB; Q10M80; -.
DR SMR; Q10M80; -.
DR STRING; 4530.OS03T0320000-01; -.
DR TCDB; 1.A.8.10.12; the major intrinsic protein (mip) family.
DR PaxDb; Q10M80; -.
DR PRIDE; Q10M80; -.
DR EnsemblPlants; Os03t0320000-01; Os03t0320000-01; Os03g0320000.
DR Gramene; Os03t0320000-01; Os03t0320000-01; Os03g0320000.
DR eggNOG; KOG0223; Eukaryota.
DR HOGENOM; CLU_100006_0_0_1; -.
DR InParanoid; Q10M80; -.
DR OMA; HGGPAVY; -.
DR Proteomes; UP000000763; Chromosome 3.
DR Proteomes; UP000059680; Chromosome 3.
DR Genevisible; Q10M80; OS.
DR GO; GO:0005783; C:endoplasmic reticulum; IEA:EnsemblPlants.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0015267; F:channel activity; IEA:InterPro.
DR GO; GO:0009846; P:pollen germination; IEA:EnsemblPlants.
DR GO; GO:0009860; P:pollen tube growth; IEA:EnsemblPlants.
DR Gene3D; 1.20.1080.10; -; 1.
DR InterPro; IPR023271; Aquaporin-like.
DR InterPro; IPR000425; MIP.
DR InterPro; IPR044226; SIP2-1-like.
DR PANTHER; PTHR47720; PTHR47720; 1.
DR Pfam; PF00230; MIP; 1.
DR SUPFAM; SSF81338; SSF81338; 1.
PE 2: Evidence at transcript level;
KW Membrane; Reference proteome; Repeat; Transmembrane; Transmembrane helix;
KW Transport.
FT CHAIN 1..250
FT /note="Aquaporin SIP2-1"
FT /id="PRO_0000286043"
FT TRANSMEM 14..34
FT /note="Helical; Name=1"
FT /evidence="ECO:0000255"
FT TRANSMEM 55..75
FT /note="Helical; Name=2"
FT /evidence="ECO:0000255"
FT TRANSMEM 95..115
FT /note="Helical; Name=3"
FT /evidence="ECO:0000255"
FT TRANSMEM 132..152
FT /note="Helical; Name=4"
FT /evidence="ECO:0000255"
FT TRANSMEM 178..200
FT /note="Helical; Name=5"
FT /evidence="ECO:0000255"
FT TRANSMEM 211..231
FT /note="Helical; Name=6"
FT /evidence="ECO:0000255"
FT MOTIF 78..80
FT /note="NPA 1"
FT MOTIF 191..193
FT /note="NPA 2"
SQ SEQUENCE 250 AA; 26849 MW; 0BF6F923323A9748 CRC64;
MSPAPPPSRG RIRPWLVVGD LVVAAMWVCA GALVKLAVYG VLGLGGRPEA DAVKVALSLV
YMFFFAWLEG FTGGASYNPL TVLAGALASR AGPSLYLFAA FVRMPAQVFG SILGVKLIRA
ALPKVGKGAP LSVGVHHGAL AEGLATFMVV IVSVTLKKKE MKGFFMKTWI SSIWKMTFHL
LSSDITGGVM NPASAFAWAY ARGDHTTFDH LLVYWLAPLQ ATLLGVWVVT LLTKPKKIEE
EADESKTKKE
