ID   SIP5_ASHGO              Reviewed;         476 AA.
AC   Q759M1;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   09-JAN-2013, sequence version 2.
DT   25-MAY-2022, entry version 84.
DE   RecName: Full=Protein SIP5;
GN   Name=SIP5; OrderedLocusNames=ADR255W; ORFNames=AGOS_ADR255W;
OS   Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS   (Yeast) (Eremothecium gossypii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX   NCBI_TaxID=284811;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=15001715; DOI=10.1126/science.1095781;
RA   Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA   Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA   Gaffney T.D., Philippsen P.;
RT   "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT   cerevisiae genome.";
RL   Science 304:304-307(2004).
RN   [2]
RP   GENOME REANNOTATION, AND SEQUENCE REVISION TO 295.
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=23749448; DOI=10.1534/g3.112.002881;
RA   Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT   "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT   loci, numerous translocations, lack of transposons, and distinct gene
RT   duplications.";
RL   G3 (Bethesda) 3:1225-1239(2013).
CC   -!- FUNCTION: May negatively regulate the SNF1 kinase. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SIP5 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AE016817; AAS52175.2; -; Genomic_DNA.
DR   RefSeq; NP_984351.2; NM_209704.2.
DR   AlphaFoldDB; Q759M1; -.
DR   STRING; 33169.AAS52175; -.
DR   EnsemblFungi; AAS52175; AAS52175; AGOS_ADR255W.
DR   GeneID; 4620513; -.
DR   KEGG; ago:AGOS_ADR255W; -.
DR   eggNOG; KOG2789; Eukaryota.
DR   HOGENOM; CLU_009068_2_0_1; -.
DR   InParanoid; Q759M1; -.
DR   OMA; ISEPANC; -.
DR   Proteomes; UP000000591; Chromosome IV.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0042149; P:cellular response to glucose starvation; IEA:EnsemblFungi.
DR   InterPro; IPR039301; Sip5/DA2.
DR   PANTHER; PTHR31315; PTHR31315; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Reference proteome.
FT   CHAIN           1..476
FT                   /note="Protein SIP5"
FT                   /id="PRO_0000333425"
FT   REGION          1..48
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          351..379
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        22..48
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   476 AA;  53075 MW;  3186607F6FD50102 CRC64;
     MGNVPGKLEA EEYGAMNGRR GGSQKQFRSL SQSSTASSGS AAADSGRSRR ATSLVGNLLS
     SGGVSRAESY GGSAYRRRVA REKDRLREQH ALRLVVRSEE TVDGGYLAPY GSYRLEKLDY
     DAPVVQGLIV ERRLAPFYTP LQDFDEGWTR EELVRVVDSL LLHAPFEEEP EEFEGVPLGN
     LGVADIDALV DKTLSRREQR RQRSKIFRAR LHRKRILWQE EENSKFLELK LEARRTGVSS
     ACLPSDDAKW DLYRNGAECP ICFLYFPEPM NVSRCCLQPI CTECFVQIKR QEPHFSHDEV
     DPAQPDEDKD PDLLISTPAS CPFCATPNFG VTYKPPADRI LGIQGGPPSS YVSACSDPPH
     HHTEPPPRRT SVAHDHSSVV TSDMIRPDWE TELIKERTKL ARRAANATAI HVSNRLVDPG
     HTRGYSNSFA SASSTYASNS SMTADFEEEM IRHVMRLSLL DQQPNATSIS PGPVDR