SIP5_ASPCL
ID SIP5_ASPCL Reviewed; 815 AA.
AC A1C3V7;
DT 20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2007, sequence version 1.
DT 25-MAY-2022, entry version 57.
DE RecName: Full=Protein sip5;
GN Name=sip5; ORFNames=ACLA_057530;
OS Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 /
OS NRRL 1 / QM 1276 / 107).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Fumigati.
OX NCBI_TaxID=344612;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1;
RX PubMed=18404212; DOI=10.1371/journal.pgen.1000046;
RA Fedorova N.D., Khaldi N., Joardar V.S., Maiti R., Amedeo P., Anderson M.J.,
RA Crabtree J., Silva J.C., Badger J.H., Albarraq A., Angiuoli S., Bussey H.,
RA Bowyer P., Cotty P.J., Dyer P.S., Egan A., Galens K., Fraser-Liggett C.M.,
RA Haas B.J., Inman J.M., Kent R., Lemieux S., Malavazi I., Orvis J.,
RA Roemer T., Ronning C.M., Sundaram J.P., Sutton G., Turner G., Venter J.C.,
RA White O.R., Whitty B.R., Youngman P., Wolfe K.H., Goldman G.H.,
RA Wortman J.R., Jiang B., Denning D.W., Nierman W.C.;
RT "Genomic islands in the pathogenic filamentous fungus Aspergillus
RT fumigatus.";
RL PLoS Genet. 4:E1000046-E1000046(2008).
CC -!- FUNCTION: May negatively regulate the snf1 kinase. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the SIP5 family. {ECO:0000305}.
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DR EMBL; DS026990; EAW15097.1; -; Genomic_DNA.
DR RefSeq; XP_001276523.1; XM_001276522.1.
DR AlphaFoldDB; A1C3V7; -.
DR STRING; 5057.CADACLAP00005499; -.
DR EnsemblFungi; EAW15097; EAW15097; ACLA_057530.
DR GeneID; 4709040; -.
DR KEGG; act:ACLA_057530; -.
DR VEuPathDB; FungiDB:ACLA_057530; -.
DR eggNOG; KOG2789; Eukaryota.
DR HOGENOM; CLU_009068_1_0_1; -.
DR OMA; CPICFLT; -.
DR OrthoDB; 642531at2759; -.
DR Proteomes; UP000006701; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR InterPro; IPR039301; Sip5/DA2.
DR PANTHER; PTHR31315; PTHR31315; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Reference proteome.
FT CHAIN 1..815
FT /note="Protein sip5"
FT /id="PRO_0000333426"
FT REGION 1..82
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 161..188
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 200..266
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 317..348
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 387..416
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 461..497
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 514..534
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 556..720
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 736..780
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..31
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 32..46
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 64..82
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 172..186
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 200..252
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 481..497
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 556..586
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 608..622
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 635..654
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 662..681
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 689..706
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 749..774
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 815 AA; 88129 MW; FB85FF4960835BDE CRC64;
MGNSQTKESR PSLSSSNRRG HQWGSSSSHG RSPYGDRHHA EGSRSRGSRP DLSMFGIGGS
SDRDVATLEH RRETKQEREA RRLEKERVAR LKERERSMRE EHVDGGYLVT QGVYVGTEDF
NKAVTRQLMI ERRLAPFWRG LNDFSDSWTE HQLMAAARGL PIPPPDEIPP ELEYKNPPRS
TEEAKESTIQ HLMVPITSRS QSYGSEASQS STPTHSLPSP TSPFASGTSS SPLFRTRAKT
LASLTSSRHG SQVDAGPKEI QLPKDPFVNG QPIEAYLYKD ATECPICFLY YPPYLNRTRC
CDQPICSECF VQIKRPDPHP PEHGETDSNA ANSTSDRDRQ ESQDGQLVSG PAACPFCVQP
EFGVTYAPPP FRRGLVYATD SSLRPTFASP VSSSSSLSSA NPPAITGRRR ATSLSANDPT
VITTDRIRPD WAQKLANARA HAARRSAAAT ALHTAAYLMN TNSSGNESRN FSLGRRGVMR
RTGTSENQSV SNRSGSPALQ ALAFLTDRRA VGPETDFAEE GGGNMAPPRN SSRRNRIDDL
EEMMMMEAIR LSLASEEERR RKEEKEAKKE AKRREKESKK AEKAARKLGV YSNNASSSAL
DVLSDPRHGK GSSSSSSMTG EDTACGKGKE VERMPPSTTN ATASPSSLEI PSDAANSSPV
AHVIEPGSSA QAATTQSLAR ELPKPSHLRH VSSASSSFSS LVDSTPDDPT GAYDGSATAT
EPMFNFRSLA AVIGDEDKGV ESTEHVEDTS SRATVASSAS GVAPSATETS GAPATGVEPV
SVETITENGD CLMPKELETR SVEITHTAPN TEATS
