SIP5_ASPFU
ID SIP5_ASPFU Reviewed; 812 AA.
AC Q4WCJ7;
DT 20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2005, sequence version 1.
DT 25-MAY-2022, entry version 77.
DE RecName: Full=Protein sip5;
GN Name=sip5; ORFNames=AFUA_8G04180;
OS Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC
OS A1100) (Aspergillus fumigatus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Fumigati.
OX NCBI_TaxID=330879;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100;
RX PubMed=16372009; DOI=10.1038/nature04332;
RA Nierman W.C., Pain A., Anderson M.J., Wortman J.R., Kim H.S., Arroyo J.,
RA Berriman M., Abe K., Archer D.B., Bermejo C., Bennett J.W., Bowyer P.,
RA Chen D., Collins M., Coulsen R., Davies R., Dyer P.S., Farman M.L.,
RA Fedorova N., Fedorova N.D., Feldblyum T.V., Fischer R., Fosker N.,
RA Fraser A., Garcia J.L., Garcia M.J., Goble A., Goldman G.H., Gomi K.,
RA Griffith-Jones S., Gwilliam R., Haas B.J., Haas H., Harris D.E.,
RA Horiuchi H., Huang J., Humphray S., Jimenez J., Keller N., Khouri H.,
RA Kitamoto K., Kobayashi T., Konzack S., Kulkarni R., Kumagai T., Lafton A.,
RA Latge J.-P., Li W., Lord A., Lu C., Majoros W.H., May G.S., Miller B.L.,
RA Mohamoud Y., Molina M., Monod M., Mouyna I., Mulligan S., Murphy L.D.,
RA O'Neil S., Paulsen I., Penalva M.A., Pertea M., Price C., Pritchard B.L.,
RA Quail M.A., Rabbinowitsch E., Rawlins N., Rajandream M.A., Reichard U.,
RA Renauld H., Robson G.D., Rodriguez de Cordoba S., Rodriguez-Pena J.M.,
RA Ronning C.M., Rutter S., Salzberg S.L., Sanchez M., Sanchez-Ferrero J.C.,
RA Saunders D., Seeger K., Squares R., Squares S., Takeuchi M., Tekaia F.,
RA Turner G., Vazquez de Aldana C.R., Weidman J., White O., Woodward J.R.,
RA Yu J.-H., Fraser C.M., Galagan J.E., Asai K., Machida M., Hall N.,
RA Barrell B.G., Denning D.W.;
RT "Genomic sequence of the pathogenic and allergenic filamentous fungus
RT Aspergillus fumigatus.";
RL Nature 438:1151-1156(2005).
CC -!- FUNCTION: May negatively regulate the snf1 kinase. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the SIP5 family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AAHF01000013; EAL85187.1; -; Genomic_DNA.
DR RefSeq; XP_747225.1; XM_742132.1.
DR AlphaFoldDB; Q4WCJ7; -.
DR STRING; 746128.CADAFUBP00008114; -.
DR EnsemblFungi; EAL85187; EAL85187; AFUA_8G04180.
DR GeneID; 3504809; -.
DR KEGG; afm:AFUA_8G04180; -.
DR VEuPathDB; FungiDB:Afu8g04180; -.
DR eggNOG; KOG2789; Eukaryota.
DR HOGENOM; CLU_009068_1_0_1; -.
DR InParanoid; Q4WCJ7; -.
DR OMA; CPICFLT; -.
DR OrthoDB; 642531at2759; -.
DR Proteomes; UP000002530; Chromosome 8.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR InterPro; IPR039301; Sip5/DA2.
DR PANTHER; PTHR31315; PTHR31315; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Reference proteome.
FT CHAIN 1..812
FT /note="Protein sip5"
FT /id="PRO_0000333427"
FT REGION 1..97
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 159..187
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 200..232
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 244..266
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 317..340
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 384..412
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 507..533
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 554..718
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 732..778
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..31
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 32..46
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 64..97
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 317..332
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 554..585
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 607..621
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 634..676
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 685..718
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 732..748
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 749..766
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 812 AA; 87899 MW; 8D90AA9CA64F9E57 CRC64;
MGNSQTKEFR PPLSSSNRRS HQWGSSSSHG RSPYSDRHHA ESSRSRGSRP DLSILGIGGS
SERDVATLEH RRETKQEREA RRLEKERAAR VKERERSMRE EHVDGGYLVT QGVYVGTEDF
NKAVTRQLMI ERRLAPFWRG LNDFSESWTE HQLMAAARGL PIPPPDEIPP ELEYKNPPKL
SGDGKEPSIQ HLMVPITSRS QSYGSEASQS STPAHSLPAP VSPIASGTST SPLFRSRAKT
LASLTTSKLG SQSDSTPKEI HLPEDPFVNG QPIEAYLYKD ATECPICFLY YPPYLNRTRC
CDQPICSECF VQIKRPDPHP PEHGEAEPNA AAAEGDRQDN QDCQLVSEPA ACPFCVQPEF
GVTYTPPPFR RGLVYATDPT LRPNFTSPVS STSSLASANA SPGTGRRRAT SLSANDPAVI
TTDRVRPDWA QKLANARAHA ARRSAAATAL HTAAYLMNST ASGNESRNFS LGRRGVMRRT
GQSETPSASS RSGSPALQAL AFLTDRRTPG HDTDSAEEGT GNLAPPRNSS RRNRIDDLEE
MMMMEAIRLS LASEEERRKK AEKEARKEAK RREKENKKAE KAARKHGFYS NNASSSALDV
PSDARLGRVA STSSSITGED ASPSKGKEVD RTSPAATAAS SQSSTEIASE SMTINPHPNV
VEQGPSAQSS MAQLSPRELP KPSHLRQVSS ASSSFSSLVE STGEDHSGAY DGNASSTEPL
FNFRSLAAVI GDEDKGDGTA EHVEDTSSKP SAEGSASSTA PVADEMPGQS TTPADPIAVK
TVAEDRDCLM PKELETQSVE ITSATRNAEA TT
