ID   SIP5_CANAL              Reviewed;         514 AA.
AC   Q5AA26; A0A1D8PDN7; Q5AAB3;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   12-APR-2017, sequence version 2.
DT   03-AUG-2022, entry version 70.
DE   RecName: Full=Protein SIP5;
GN   Name=SIP5; OrderedLocusNames=CAALFM_C105910WA;
GN   ORFNames=CaO19.2458, CaO19.9995;
OS   Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX   NCBI_TaxID=237561;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=15123810; DOI=10.1073/pnas.0401648101;
RA   Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B.,
RA   Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W.,
RA   Scherer S.;
RT   "The diploid genome sequence of Candida albicans.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=17419877; DOI=10.1186/gb-2007-8-4-r52;
RA   van het Hoog M., Rast T.J., Martchenko M., Grindle S., Dignard D.,
RA   Hogues H., Cuomo C., Berriman M., Scherer S., Magee B.B., Whiteway M.,
RA   Chibana H., Nantel A., Magee P.T.;
RT   "Assembly of the Candida albicans genome into sixteen supercontigs aligned
RT   on the eight chromosomes.";
RL   Genome Biol. 8:RESEARCH52.1-RESEARCH52.12(2007).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=24025428; DOI=10.1186/gb-2013-14-9-r97;
RA   Muzzey D., Schwartz K., Weissman J.S., Sherlock G.;
RT   "Assembly of a phased diploid Candida albicans genome facilitates allele-
RT   specific measurements and provides a simple model for repeat and indel
RT   structure.";
RL   Genome Biol. 14:RESEARCH97.1-RESEARCH97.14(2013).
CC   -!- FUNCTION: May negatively regulate the SNF1 kinase. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SIP5 family. {ECO:0000305}.
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DR   EMBL; CP017623; AOW26255.1; -; Genomic_DNA.
DR   RefSeq; XP_718480.2; XM_713387.2.
DR   AlphaFoldDB; Q5AA26; -.
DR   BioGRID; 1222848; 1.
DR   STRING; 237561.Q5AA26; -.
DR   PRIDE; Q5AA26; -.
DR   GeneID; 3639865; -.
DR   KEGG; cal:CAALFM_C105910WA; -.
DR   CGD; CAL0000178486; SIP5.
DR   VEuPathDB; FungiDB:C1_05910W_A; -.
DR   eggNOG; KOG2789; Eukaryota.
DR   HOGENOM; CLU_009068_0_0_1; -.
DR   InParanoid; Q5AA26; -.
DR   OrthoDB; 642531at2759; -.
DR   PRO; PR:Q5AA26; -.
DR   Proteomes; UP000000559; Chromosome 1.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   InterPro; IPR039301; Sip5/DA2.
DR   PANTHER; PTHR31315; PTHR31315; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Reference proteome.
FT   CHAIN           1..514
FT                   /note="Protein SIP5"
FT                   /id="PRO_0000333432"
FT   REGION          1..79
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          340..396
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          442..481
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..61
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        62..79
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        347..386
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   514 AA;  57246 MW;  D187047FDAB07C21 CRC64;
     MGNVPAKETR SRSSSSVSDY RNSTSSTTHG SSSSTSSKRR NTTSSLYGIV SSATSSSNHH
     NRSGSHDLRK LKRQEEKEQA QIQHYMQLIV KFNESVDGGY LAPFGTYKSN LDYDCDIVRN
     LIINRKLSPF FTPLQDFDES WTDDELCILL GQLTLHALEP GYNNDDDEEE DDIDNHKIHK
     SANYYKRQEE KAKLKSLINK VKELQKDEEQ KYFDEKQKNF NKDCPSRDLL LRLYRNASEC
     PICFLYYPKH LNISRCCLQP ICSECFVQIK RLDPHPPHDD QSNQEAGELP HRLISEPANC
     PYCASPDFGV TYEPPIDIHT GIDGIKPGDY RVSPPIVEES ESAIDDDGDN SSNGSTTGKG
     EITSNSATAA AAATATPPPV NSISPKKNSL KKRRGSLAAN APGVITIDMI RPDWETKLNS
     ARSKLARKAA TASAIHASNL LLDDNSNSNS NNGNGNNSGN NRRRNNSSSG RSGSFGGSNN
     RYATVEQRMI EEAMRLSILD EEERKRNANK ENKK