ID   SIP5_NEOFI              Reviewed;         812 AA.
AC   A1DB29;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 1.
DT   25-MAY-2022, entry version 63.
DE   RecName: Full=Protein sip5;
GN   Name=sip5; ORFNames=NFIA_096910;
OS   Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164
OS   / JCM 1740 / NRRL 181 / WB 181) (Aspergillus fischerianus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Fumigati.
OX   NCBI_TaxID=331117;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181
RC   / WB 181;
RX   PubMed=18404212; DOI=10.1371/journal.pgen.1000046;
RA   Fedorova N.D., Khaldi N., Joardar V.S., Maiti R., Amedeo P., Anderson M.J.,
RA   Crabtree J., Silva J.C., Badger J.H., Albarraq A., Angiuoli S., Bussey H.,
RA   Bowyer P., Cotty P.J., Dyer P.S., Egan A., Galens K., Fraser-Liggett C.M.,
RA   Haas B.J., Inman J.M., Kent R., Lemieux S., Malavazi I., Orvis J.,
RA   Roemer T., Ronning C.M., Sundaram J.P., Sutton G., Turner G., Venter J.C.,
RA   White O.R., Whitty B.R., Youngman P., Wolfe K.H., Goldman G.H.,
RA   Wortman J.R., Jiang B., Denning D.W., Nierman W.C.;
RT   "Genomic islands in the pathogenic filamentous fungus Aspergillus
RT   fumigatus.";
RL   PLoS Genet. 4:E1000046-E1000046(2008).
CC   -!- FUNCTION: May negatively regulate the snf1 kinase. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SIP5 family. {ECO:0000305}.
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DR   EMBL; DS027694; EAW20069.1; -; Genomic_DNA.
DR   RefSeq; XP_001261966.1; XM_001261965.1.
DR   AlphaFoldDB; A1DB29; -.
DR   STRING; 36630.CADNFIAP00008566; -.
DR   EnsemblFungi; EAW20069; EAW20069; NFIA_096910.
DR   GeneID; 4588529; -.
DR   KEGG; nfi:NFIA_096910; -.
DR   VEuPathDB; FungiDB:NFIA_096910; -.
DR   eggNOG; KOG2789; Eukaryota.
DR   HOGENOM; CLU_009068_1_0_1; -.
DR   OMA; CPICFLT; -.
DR   OrthoDB; 642531at2759; -.
DR   Proteomes; UP000006702; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   InterPro; IPR039301; Sip5/DA2.
DR   PANTHER; PTHR31315; PTHR31315; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Reference proteome.
FT   CHAIN           1..812
FT                   /note="Protein sip5"
FT                   /id="PRO_0000333438"
FT   REGION          1..97
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          160..187
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          200..232
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          317..339
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          385..412
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          508..532
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          554..718
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          732..812
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..31
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        32..46
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        64..97
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        172..186
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        317..332
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        554..585
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        606..621
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        634..673
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        685..718
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        732..748
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        796..812
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   812 AA;  87952 MW;  8F38900F4D5947BD CRC64;
     MGNSQTKEFR PPLSSSNRRS HQWGSSSSHG RSPYSDRHHA ESSRSRGSRP DLSILGIGGS
     SERDVATLEH RRETKQEREA RRLEKERAAR VKERERSMRE EHVDGGYLVT QGVYVGAEDF
     NKVVTRQLMI ERRLAPFWRG LNDFSESWTE HQLMAAARGL PIPPPDEIPP ELEYKNPPKL
     TEDGKESSIQ HLMVPITSRS QSYGSEASQS STPAHSLPTP VSPIASGTST SPLFRSRAKT
     LASLTTSKLG SQIDSTPKEI HLPEDPFVNG QPIEAYLYKD ATECPICFLY YPPYLNRTRC
     CDQPICSECF VQIKRPDPHP PEHGEAEPNA TAAEGDRQDN QDCQLVSEPA ACPFCVQPEF
     GVTYTPPPFR RGLVYATDPT LRPNFASPVS STSSLASANA PPGTGRRRAT SLSANDPTVI
     TTDRVRPDWA QKLANARAHA ARRSAAATAL HTAAYLMNST ASGNESRNFG LGRRGVMRRT
     GQSETPSASS RSGSPALQAL AFLTDRRTPG HETDSAEEGA GNLAPPRNSS RRNRIDDLEE
     MMMMEAIRLS LASEEERRKK AEKEARKEAK RREKESKKAE KAARKHGFYS NNASSSALDV
     PSDARLGRVT SSSSSITGED ASPSKGKEVD RASPSATAAS SQSSTEIASD SMTINPHPNV
     VEHGSSAQSL MAQPSAREPP KPSHLRQVSS ASSSFSSLVE STGEDHSGAY DGNASSTEPL
     FNFRSLAAVI GDEDKGDETA EHVEDTSSKP SAEGSASSAA PVADEMLGQS TAPADPIAVG
     TVAEERDCLM PKELETQSVE ITSATRNTEA TT