ID   SIP5_PICGU              Reviewed;         433 AA.
AC   A5DQJ8;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   10-FEB-2009, sequence version 2.
DT   25-MAY-2022, entry version 54.
DE   RecName: Full=Protein SIP5;
GN   Name=SIP5; ORFNames=PGUG_05549;
OS   Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539
OS   / NBRC 10279 / NRRL Y-324) (Yeast) (Candida guilliermondii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Meyerozyma.
OX   NCBI_TaxID=294746;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324;
RX   PubMed=19465905; DOI=10.1038/nature08064;
RA   Butler G., Rasmussen M.D., Lin M.F., Santos M.A.S., Sakthikumar S.,
RA   Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA   Arnaud M.B., Bates S., Brown A.J.P., Brunke S., Costanzo M.C.,
RA   Fitzpatrick D.A., de Groot P.W.J., Harris D., Hoyer L.L., Hube B.,
RA   Klis F.M., Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M.,
RA   Nikolaou E., Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F.,
RA   Sherlock G., Shah P., Silverstein K.A.T., Skrzypek M.S., Soll D.,
RA   Staggs R., Stansfield I., Stumpf M.P.H., Sudbery P.E., Srikantha T.,
RA   Zeng Q., Berman J., Berriman M., Heitman J., Gow N.A.R., Lorenz M.C.,
RA   Birren B.W., Kellis M., Cuomo C.A.;
RT   "Evolution of pathogenicity and sexual reproduction in eight Candida
RT   genomes.";
RL   Nature 459:657-662(2009).
CC   -!- FUNCTION: May negatively regulate the SNF1 kinase. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SIP5 family. {ECO:0000305}.
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DR   EMBL; CH408161; EDK41451.2; -; Genomic_DNA.
DR   RefSeq; XP_001482529.1; XM_001482479.1.
DR   AlphaFoldDB; A5DQJ8; -.
DR   STRING; 4929.XP_001482529.1; -.
DR   EnsemblFungi; EDK41451; EDK41451; PGUG_05549.
DR   GeneID; 5124287; -.
DR   KEGG; pgu:PGUG_05549; -.
DR   eggNOG; KOG2789; Eukaryota.
DR   HOGENOM; CLU_009068_2_0_1; -.
DR   InParanoid; A5DQJ8; -.
DR   OMA; ISEPANC; -.
DR   OrthoDB; 642531at2759; -.
DR   Proteomes; UP000001997; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   InterPro; IPR039301; Sip5/DA2.
DR   PANTHER; PTHR31315; PTHR31315; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Reference proteome.
FT   CHAIN           1..433
FT                   /note="Protein SIP5"
FT                   /id="PRO_0000333441"
FT   REGION          1..49
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          305..334
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          377..404
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        8..35
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        307..331
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        377..402
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   433 AA;  49090 MW;  D0E9CC5A33443059 CRC64;
     MGNVPAKEGR SRSSTFSGTG AEIVTRSARR NTTSSADVKK SSRKSEEKDR LREKHWRDLV
     VRLHENVDGG YLAPYGTYKS NLDFDTEVVR RLVINRQLAP FYTPLNDFDP TWTTEELLVI
     LSQLPLHSIE DAYSDAESEE DDVDNHKIHK SNNYYRRQEQ KRKLKHSMET AKQAQKEEET
     ALLHQKMLLK QGGQVSSSLP SKDLLLRLYS DASECPICFL YYPSNLNISR CCLQPICTEC
     FVQIKRLDPH PPHDDASNQP NGDSLPHTLI SEPAHCPYCA MADFGVIYDP LSDLRTGING
     KCSPGEYRMP EHSDAKSDVQ SVKKRPRRKS MAATDPGIIT VDNIRPDWEQ KLISAKNKLA
     RKAAAASAIH ASNLILNGDD SQTSSQQSRL RSRNSGGQTY NTIEERMIEE ALRLSLLDEE
     ERRRKERENS SKD