ID   SIP5_VANPO              Reviewed;         479 AA.
AC   A7TL97;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   02-OCT-2007, sequence version 1.
DT   25-MAY-2022, entry version 49.
DE   RecName: Full=Protein SIP5;
GN   Name=SIP5; ORFNames=Kpol_1041p30;
OS   Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294 / BCRC 21397 / CBS
OS   2163 / NBRC 10782 / NRRL Y-8283 / UCD 57-17) (Kluyveromyces polysporus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Vanderwaltozyma.
OX   NCBI_TaxID=436907;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 22028 / DSM 70294 / BCRC 21397 / CBS 2163 / NBRC 10782 / NRRL
RC   Y-8283 / UCD 57-17;
RX   PubMed=17494770; DOI=10.1073/pnas.0608218104;
RA   Scannell D.R., Frank A.C., Conant G.C., Byrne K.P., Woolfit M., Wolfe K.H.;
RT   "Independent sorting-out of thousands of duplicated gene pairs in two yeast
RT   species descended from a whole-genome duplication.";
RL   Proc. Natl. Acad. Sci. U.S.A. 104:8397-8402(2007).
CC   -!- FUNCTION: May negatively regulate the SNF1 kinase. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SIP5 family. {ECO:0000305}.
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DR   EMBL; DS480413; EDO16972.1; -; Genomic_DNA.
DR   RefSeq; XP_001644830.1; XM_001644780.1.
DR   AlphaFoldDB; A7TL97; -.
DR   STRING; 436907.A7TL97; -.
DR   EnsemblFungi; EDO16972; EDO16972; Kpol_1041p30.
DR   GeneID; 5545157; -.
DR   KEGG; vpo:Kpol_1041p30; -.
DR   eggNOG; KOG2789; Eukaryota.
DR   HOGENOM; CLU_009068_2_0_1; -.
DR   InParanoid; A7TL97; -.
DR   OMA; ISEPANC; -.
DR   OrthoDB; 642531at2759; -.
DR   PhylomeDB; A7TL97; -.
DR   Proteomes; UP000000267; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   InterPro; IPR039301; Sip5/DA2.
DR   PANTHER; PTHR31315; PTHR31315; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Reference proteome.
FT   CHAIN           1..479
FT                   /note="Protein SIP5"
FT                   /id="PRO_0000333444"
FT   REGION          1..62
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   479 AA;  54375 MW;  185B3D713E42EEB1 CRC64;
     MGNVPTKLEE PQNPSSRLKS SSFSNSVSGN SDITDSPGSG NGRSSSQTKL NNARSKKKNA
     SLSNGLLKST TISSRKKDQL DREQFKEDHA AELLVKYYES VDGGFLAPFG CYSLEKLNYN
     PKIVKKLIIE RKLAPFYTPL QDFNDNWTDE ELIKIIDGLP LHASFNESLE EFEDIPTGDL
     KSKDFDYLID SSSLSKREQK KLHSKIFKAR LHKKRIAWQE MENTYFLEKK LSNKNILSKS
     KDSSEDMNNH ISNSSNDILN NIDISLPNDD LKLSLYQSGI ECPICFLYYP KNLNYSKCCQ
     QPICTECFVQ IKRALPHFPH DDNEHNNEDD SEKDPHLLIS EPANCPYCAT PNFTISYSPI
     ASRKTGINGV KQFYYKPPKA NDDANLSNNT AKPVYLTSDT IRPDWEDKLN KERSRLQRRA
     ANATAIHVSN QLISPGRSEN NEIPSNLKEL ENQMIEQAIK LSLQDRKQNE SGSRKKSSK