ID   SIP5_YARLI              Reviewed;         497 AA.
AC   Q6CEU8;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   25-MAY-2022, entry version 71.
DE   RecName: Full=Protein SIP5;
GN   Name=SIP5; OrderedLocusNames=YALI0B12782g;
OS   Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Dipodascaceae; Yarrowia.
OX   NCBI_TaxID=284591;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CLIB 122 / E 150;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: May negatively regulate the SNF1 kinase. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SIP5 family. {ECO:0000305}.
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DR   EMBL; CR382128; CAG83065.1; -; Genomic_DNA.
DR   RefSeq; XP_500814.1; XM_500814.1.
DR   AlphaFoldDB; Q6CEU8; -.
DR   STRING; 4952.CAG83065; -.
DR   EnsemblFungi; CAG83065; CAG83065; YALI0_B12782g.
DR   GeneID; 2906722; -.
DR   KEGG; yli:YALI0B12782g; -.
DR   VEuPathDB; FungiDB:YALI0_B12782g; -.
DR   HOGENOM; CLU_009068_2_0_1; -.
DR   InParanoid; Q6CEU8; -.
DR   OMA; ISEPANC; -.
DR   Proteomes; UP000001300; Chromosome B.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   InterPro; IPR039301; Sip5/DA2.
DR   PANTHER; PTHR31315; PTHR31315; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Reference proteome.
FT   CHAIN           1..497
FT                   /note="Protein SIP5"
FT                   /id="PRO_0000333445"
FT   REGION          1..52
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          112..172
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          185..240
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          348..371
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          438..497
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        13..47
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        114..144
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        481..497
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   497 AA;  54473 MW;  65A7ABF851464603 CRC64;
     MGNVPGKEQQ VRNARSVSED YHREGQVRSK RPSAPREKKR EPRVFVDPNE QVDGGYLVPQ
     GVYTGPQDFD ILVVKSLMTS RKLAPFFKGL QDYEEEWTDH QLMAAIRGFP IPSAASESPT
     TESTDTKDAS ASTSTPHAIS TPSHLSPPTA PPQVAISPPR HTLSSNNPFR DPLEHMSHLR
     IDLDNTTFSQ SAPTPSWMRS GEPDQEDGDE LINPGILQSP PSREAPKPPP SRQRAKTLTN
     KEPPLMVKIY RDPIECPICF LYYPNSLNMT RCCAQPICSE CFVQMKRAEP HPRHDEPEPD
     TLLGQLDLIS EPTACPYCAM SDFGVVYSPR HGPGAKAAGA NSADAAAAKG NGDESAIDDS
     GDSSDGIDTT NMDDVADKLM HMSGAKRRSS ISVTNPNVVT VDRVRPDWSK TLAAARARAA
     RKAATANALH ATAFVEGGNG EVAGSSRSSR RTRQNHEQRQ AARAQELEQI MLSEAMRLSM
     LESQEAEEKR SREQESK